Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Charles Hillier"'
Autor:
Alan J Thompson, Charles Wade, Nevin John, Jeremy Chataway, Gavin Giovannoni, Rachael Hunter, Sreedharan Harikrishnan, Floriana De Angelis, Olga Ciccarelli, Eli Silber, John Greenwood, Thomas Williams, Martin Duddy, Basil Sharrack, Annie Hawton, Siddharthan Chandran, Sue Pavitt, Paul Gallagher, Ian Galea, Jennifer M Nicholas, Tarunya Arun, Miriam Mattoscio, Richard Nicholas, Neil Robertson, Carolyn Young, Jeremy Hobart, David Rog, Owen Pearson, Anisha Doshi, Timothy Harrower, Leonora Fisniku, Ruth Geraldes, Nikos Evangelou, Judy Beveridge, Matthew Craner, Don Mahad, Stefano Pluchino, Suresh Chhetri, Susan Tebbs, Marie Braisher, Seema Kalra, Charles Hillier, Chris Frost, Gavin McDonnell, Stuart J Nixon, Helen L Ford, Jeban Ganesalingam, Claire Rice, Alberto Calvi, Cord Spilker, Abdullah Shehu, Martin Lee, James Blackstone, Alessia Bianchi, Agne Straukiene, Gil Barton, Fayyaz Ahmed, Dawn Lyle, Ekaterina Bordea, Sean Apap Mangion, Rachel Merry, Elisabeth Jarman
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Introduction There remains a high unmet need for disease-modifying therapies that can impact disability progression in secondary progressive multiple sclerosis (SPMS). Following positive results of the phase 2 MS-STAT study, the MS-STAT2 phase 3 tria
Externí odkaz:
https://doaj.org/article/69619bde66e34a6986cbeaf0b8bdc802
Publikováno v:
Echo Research and Practice, Vol 7, Iss 3, Pp K17-K20 (2020)
Young stroke patients should be investigated thoroughly to look for cardiac and extra-cardiac sources of emboli. We present a patient who was investigated for a cardiac source of emboli following an ischemic stroke. She was found to have a small pate
Externí odkaz:
https://doaj.org/article/8ecac076871b4db9a50bab3e151cfafd
Autor:
Burcu Anar, Theo Sanderson, Colin Herd, Julian C. Rayner, Jyoti S. Choudhary, Tom Metcalf, Oliver Billker, Lu Yu, Charles Hillier, Mercedes Pardo Calvo, Ellen Bushell
Publikováno v:
SSRN Electronic Journal.
Malaria represents a major global health issue, and the identification and prioritisation of new intervention targets remains an urgent priority. This search is significantly hampered by the fact that over a third of the genes of the malaria-causing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eb7a135ff3a5c94c109a7645089045d
https://doi.org/10.2139/ssrn.3314563
https://doi.org/10.2139/ssrn.3314563
Autor:
Charles Hillier, Rebecca Scott, Charlotte Thomas, Fern Thomas, Kelly Jones, Sarah Brenton, Louise Fazakarley, Jo Hickson, Sarah Collyer, Sarah Thomas, Peter Thomas, Steve Perring
Publikováno v:
BMJ Open
ObjectivesWhile the health and well-being benefits of physical activity are recognised, people with multiple sclerosis (MS) often face greater barriers than the general population. The Nintendo Wii potentially offers a fun, convenient way of overcomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846d843e228a9f1987f5a099e14e4ff0
https://pubmed.ncbi.nlm.nih.gov/28954791
https://pubmed.ncbi.nlm.nih.gov/28954791
Autor:
Mercedes Pardo, Colin Herd, Jyoti S. Choudhary, Julian C. Rayner, Lu Yu, Charles Hillier, Theo Sanderson, Oliver Billker, Ellen Bushell, Tom Metcalf, Burcu Anar
Publikováno v:
Cell Reports
Summary Malaria represents a major global health issue, and the identification of new intervention targets remains an urgent priority. This search is hampered by more than one-third of the genes of malaria-causing Plasmodium parasites being uncharact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34498230adf2ecbcd96e0afa19c91e43
https://doi.org/10.1016/j.celrep.2019.07.019
https://doi.org/10.1016/j.celrep.2019.07.019
Autor:
Bénédicte Dubois, Lucia Corrado, Deborah F. Mason, Allan G. Kermode, Pentti J. Tienari, Annette Bang Oturai, Charles Hillier, Adrian J. Ivinson, Stephen L. Hauser, Ashley Beecham, Jeannette Lechner-Scott, Vincent Thijs, Jonathan L. Haines, Sarah Edkins, Alexander T. Dilthey, Daniele Cusi, Guy Nagels, David A. Hafler, Mark Slee, Petra Nilsson, James S. Wiley, Lou Brundin, Amy Strange, Elizabeth Visser, Mireia Sospedra, Athena Hadjixenofontos, Sergio E. Baranzini, Jenny Link, Robert Andrews, Viola Biberacher, Helle Bach Søndergaard, Vittorio Martinelli, Tomas Olsson, Gillian L Hall, Stephen Sawcer, Stacy J. Caillier, Per Soelberg Sørensen, Céline Bellenguez, Cornelia M. van Duijn, Frauke Zipp, Nikolaos A. Patsopoulos, Cristin McCabe, Colin Freeman, Simon Broadley, Luisa Bernardinelli, Margaret A. Pericak-Vance, Jan Hillert, Wassila Carpentier, Sandip Shaunak, Anne Spurkland, Barnaby Fiddes, Judith Field, Jan Lycke, Christina M. Lill, Federica Esposito, Ioanna Konidari, Elisabeth Gulowsen Celius, Christian Gieger, Helmut Butzkueven, Ling Shen, James F. Wilson, Magdalena Lindén, Tejas S. Shah, Amie Baker, Dionysia K. Xifara, Hong Quach, Laura Bergamaschi, Rogier Q. Hintzen, Jacob L. McCauley, Janna Saarela, J W Thorpe, Christine Lebrun-Frenay, Felix Luessi, Sandra D'Alfonso, B. E. Kendall, Helga Westerlind, Giancarlo Comi, Nathalie Schnetz-Boutaud, Paola Brambilla, Chris Cotsapas, Anders Hamsten, William Camu, Achim Berthele, Kjell-Morten Myhr, Clive Hawkins, Richard Nicholas, James Harley, Carl A. Anderson, Keijo Koivisto, Irene Coman, Neil Robertson, Hakon Hakonarson, Finn Sellebjerg, Fredrik Piehl, Alessia Di Sapio, Loukas Moutsianas, Mehdi Alizadeh, Lars Alfredsson, Catherine Schaefer, David Rog, Virpi Leppa, C. Martin, Bruce A.C. Cree, Christopher Halfpenny, Irina Elovaara, Filippo Martinelli-Boneschi, Cordelia Langford, Hanne F. Harbo, Wim Robberecht, Isabelle Cournu-Rebeix, Steve Vucic, Izaura Lima Bomfim, Irene Y. Frohlich, Michelle Lee, Bertrand Fontaine, Bernhard Hemmer, Eva Zindler, Chris C. A. Spencer, Malin Larsson, Simon Shields, Ilijas Jelcic, Juliane Winkelmann, Jorge R. Oksenberg, Alastair Wilkins, Silvia Delgado, Volker Siffrin, Helena C. Kronsbein, Bruno Brochet, Panos Deloukas, Daniela Galimberti, Nikos Evangelou, Rebecca C. Selter, Maja Jagodic, Martin Duddy, Timothy Harrower, Per Hall, Nadia Barizzone, Siân Price, Matti Pirinen, Pierre-Antoine Gourraud, Thomas M.C. Binder, Giuseppe Liberatore, Mark Lathrop, M.-M. Hoshi, Garrett Hellenthal, Melissa Sorosina, Thomas Korn, Clara Guaschino, Roland Martin, Jeremy Hobart, Marco Salvetti, Peter Donnelly, Ingrid Kockum, An Goris, Alastair Compston, Mariaemma Rodegher, Dorothea Buck, Clara P. Manrique, Christiane Graetz, Benedicte A. Lie, Trevor J. Kilpatrick, Andrew Graham, Anu Kemppinen, Maria Ban, Gil McVean, John Zajicek, Hannah Blackburn, Mary F. Davis, Emilie Sundqvist, Bruce V. Taylor, Maurizio Leone, Lisa F. Barcellos, Fabio Macciardi, Gilles Defer, Vincent Damotte, Satu Männistö, Graeme J. Stewart, Gordon Mazibrada, Inger Lise Mero, Andre Franke, Philip L. De Jager, Verena Grummel, Mauri Reunanen, David R. Booth, Anna Ticca, Angela Jochim, Leentje Cosemans, Julia Y Mescheriakova, Cristina Agliardi, Paola Cavalla, Jeffrey C. Barrett, Sarah E. Hunt, Gavin Band
Publikováno v:
Nature Genetics
Nature Genetics, Nature Publishing Group, 2013, 45 (11), pp.1353-1360. ⟨10.1038/ng.2770⟩
Beecham, A H, Patsopoulos, N A, Xifara, D K, Davis, M F, Kemppinen, A, Cotsapas, C, Shah, T S, Spencer, C, Booth, D, Goris, A, Oturai, A, Saarela, J, Fontaine, B, Hemmer, B, Martin, C, Zipp, F, D'Alfonso, S, Martinelli-Boneschi, F, Taylor, B, Harbo, H F, Kockum, I, Hillert, J, Olsson, T, Ban, M, Oksenberg, J R, Hintzen, R, Barcellos, L F, Agliardi, C, Alfredsson, L, Alizadeh, M, Anderson, C, Andrews, R, Søndergaard, H B, Baker, A, Band, G, Baranzini, S E, Barizzone, N, Barrett, J, Bellenguez, C, Bergamaschi, L, Bernardinelli, L, Berthele, A, Biberacher, V, Binder, T M C, Blackburn, H, Bomfim, I L, Brambilla, P, Broadley, S, Wilson, J F & Henderson, P 2013, ' Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis ', Nature Genetics, vol. 45, no. 11, pp. 1353-60 . https://doi.org/10.1038/ng.2770
Nature genetics
Nature Genetics, 2013, 45 (11), pp.1353-1360. ⟨10.1038/ng.2770⟩
Nature Genetics, 45(11), 1353-+. Nature Publishing Group
Nature Genetics, Nature Publishing Group, 2013, 45 (11), pp.1353-1360. ⟨10.1038/ng.2770⟩
Beecham, A H, Patsopoulos, N A, Xifara, D K, Davis, M F, Kemppinen, A, Cotsapas, C, Shah, T S, Spencer, C, Booth, D, Goris, A, Oturai, A, Saarela, J, Fontaine, B, Hemmer, B, Martin, C, Zipp, F, D'Alfonso, S, Martinelli-Boneschi, F, Taylor, B, Harbo, H F, Kockum, I, Hillert, J, Olsson, T, Ban, M, Oksenberg, J R, Hintzen, R, Barcellos, L F, Agliardi, C, Alfredsson, L, Alizadeh, M, Anderson, C, Andrews, R, Søndergaard, H B, Baker, A, Band, G, Baranzini, S E, Barizzone, N, Barrett, J, Bellenguez, C, Bergamaschi, L, Bernardinelli, L, Berthele, A, Biberacher, V, Binder, T M C, Blackburn, H, Bomfim, I L, Brambilla, P, Broadley, S, Wilson, J F & Henderson, P 2013, ' Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis ', Nature Genetics, vol. 45, no. 11, pp. 1353-60 . https://doi.org/10.1038/ng.2770
Nature genetics
Nature Genetics, 2013, 45 (11), pp.1353-1360. ⟨10.1038/ng.2770⟩
Nature Genetics, 45(11), 1353-+. Nature Publishing Group
International audience; Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0 × 10(-4))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaed6c6a6596c74a380f29f543038e03
https://doi.org/10.1038/ng.2770
https://doi.org/10.1038/ng.2770
Autor:
J. Cole, Charles Hillier, G. Burke, K. Bushby, M. Sampson, L. Bridges, Rita Barresi, Simon Hammans
Publikováno v:
Neuromuscular Disorders. 20:407-410
Mutations in the gene encoding muscle-specific calpain 3 protease cause limb girdle muscular dystrophy type 2A. Calpainopathy is characterised by progressive symmetrical atrophy of pelvic, scapular and trunk muscles with an elevated creatine kinase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99be3ef510882fbda0b61ad9e9e6a1ea
https://doi.org/10.1016/j.nmd.2010.04.006
https://doi.org/10.1016/j.nmd.2010.04.006
Autor:
Nicholas Cortes, Daniel Calladine, Jacqueline Palace, Maria Isabel Leite, John S. Elston, Imran H. Yusuf, Matthew Donati, Charles Hillier, Chetan K. Patel, Nicola Jones, Robert Munneke, J Kitley, Bethan Non Matthews, Jithin George
Publikováno v:
JAMA neurology. 71(11)
IMPORTANCE: Patients with neuromyelitis optica who have aquaporin-4 antibodies are being identified and receiving immunosuppressant treatment earlier and more aggressively as a result of increasing awareness of the importance of preventing relapses r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0cf800d82e3a4dddcf8ad966d7252c
https://pubmed.ncbi.nlm.nih.gov/25199567
https://pubmed.ncbi.nlm.nih.gov/25199567
Autor:
Sarah Thomas, Charles Hillier, Louise Fazakarley, Rebecca Scott, Sarah Brenton, Kathleen Galvin, Sarah Collyer, Peter Thomas, Steve Perring
Publikováno v:
BMJ Open
Introduction The benefits of physical activity for people with multiple sclerosis (pwMS) have been recognised. However, exercise regimens can be difficult to maintain over the longer term and pwMS may face unique barriers to physical activity engagem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235abec8e3dc42e5c23f1675328bce05
Autor:
Rosemary Jones, Charles Hillier, Roger Baker, Sarah Thomas, Paula Kersten, Angela Davies Smith, Peter Thomas, Kathleen Galvin, Alison Nock, Colin Green, Vicky Slingsby
Publikováno v:
Journal of Neurology, Neurosurgery, and Psychiatry
Background Fatigue is a common and troubling symptom for people with multiple sclerosis (MS). Aim To evaluate the effectiveness and cost-effectiveness of a six-session group-based programme for managing MS-fatigue (Fatigue: Applying Cognitive behavio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd0905ec061fcc9c7cea2d65e3f5b9e
https://pubmed.ncbi.nlm.nih.gov/23695501
https://pubmed.ncbi.nlm.nih.gov/23695501