Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Charles Hetru"'
Autor:
Franck Coste, Cordula Kemp, Vanessa Bobezeau, Charles Hetru, Christine Kellenberger, Jean-Luc Imler, Alain Roussel
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33416 (2012)
BACKGROUND:The Drosophila melanogaster gene CG11501 is up regulated after a septic injury and was proposed to act as a negative regulator of the JAK/STAT signaling pathway. Diedel, the CG11501 gene product, is a small protein of 115 residues with 10
Externí odkaz:
https://doaj.org/article/5b925592351246e4805884a73a66bf38
Autor:
Delphine Galiana, Laurent Troxler, Kwang-Zin Lee, Stanislava Chtarbanova, Olivier Lamiable, Carine Meignin, Jules A. Hoffmann, Charles Hetru, Laurent Daeffler, Jean-Luc Imler
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2014, 88 (24), pp.14057-14069. ⟨10.1128/jvi.02320-14⟩
Journal of Virology, American Society for Microbiology, 2014, 88 (24), pp.14057-14069. ⟨10.1128/jvi.02320-14⟩
Drosophila C virus (DCV) is a positive-sense RNA virus belonging to the Dicistroviridae family. This natural pathogen of the model organism Drosophila melanogaster is commonly used to investigate antiviral host defense in flies, which involves both R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b9d3d4c0c3bea460ff3ac377026671
https://doi.org/10.1128/jvi.02320-14
https://doi.org/10.1128/jvi.02320-14
Publikováno v:
Nature Reviews Immunology. 7:862-874
A hallmark of the potent, multifaceted antimicrobial defence of Drosophila melanogaster is the challenge-induced synthesis of several families of antimicrobial peptides by cells in the fat body. The basic mechanisms of recognition of various types of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f441d11b1edf8404ad2d2e9967ade74
https://doi.org/10.1038/nri2194
https://doi.org/10.1038/nri2194
Autor:
Dan Hultmark, Michael R. Kanost, J-L Imler, Charles Hetru, Zhen Zou, Graham J. Thompson, Haobo Jiang, Yanping Chen, Jay D. Evans, Kate Aronstein
Publikováno v:
Insect Molecular Biology
Social insects are able to mount both group-level and individual defences against pathogens. Here we focus on individual defences, by presenting a genome-wide analysis of immunity in a social insect, the honey bee Apis mellifera. We present honey bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262d8573a6ae56bae2a383d897c40e07
Autor:
Johanna Ulvila, Charles Hetru, Stephanie L. Conto, Alan Pearson, R. Alan B. Ezekowitz, Jean-Marc Reichhart, Nadine T. Nehme, Charles Strom, Marie Meister, Dominique Ferrandon, Jules A. Hoffmann, Thilo Stehle, Christine Kocks, Ju Hyun Cho, Mika Rämet, Lynda M. Stuart
Publikováno v:
Cell. 123(2):335-346
SummaryPhagocytosis is a complex, evolutionarily conserved process that plays a central role in host defense against infection. We have identified a predicted transmembrane protein, Eater, which is involved in phagocytosis in Drosophila. Transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d181b384ea5bd979b2384a8f1a98f4b0
Autor:
Jean-Luc, Imler, Dominique, Ferrandon, Julien, Royet, Jean-Marc, Reichhart, Charles, Hetru, Jules A, Hoffmann
Publikováno v:
Journal of Endotoxin Research. 10:241-246
The multifaceted response of the fruitfly Drosophila melanogaster to infection by a wide range of microbes is complex and remarkably efficient. Its most prominent aspect is the immune-inducible expression of a set of potent antimicrobial peptides. Ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0b56259e58e8d429aa320893816bfd
https://doi.org/10.1177/09680519040100040701
https://doi.org/10.1177/09680519040100040701
Publikováno v:
Comptes Rendus Biologies. 327:557-570
In recent years, the innate immune system has emerged from the shadow of adaptive immune responses as a major area of research in its own right. One of the most significant model systems that has been used to investigate this phenomenon has been the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a0d7d333380963f70cc629fc570be4
https://doi.org/10.1016/j.crvi.2004.03.007
https://doi.org/10.1016/j.crvi.2004.03.007
Autor:
Gareth J Lycett, Andrey Rzhetsky, Kenneth D. Vernick, Christian von Mering, Jiannong Xu, Frank H. Collins, Claudia Blass, Jules A. Hoffmann, Peer Bork, Stefan M. Kanzok, Jean-Marc Reichhart, Elena A. Levashina, Thanasis G. Loukeris, Stephan Meister, Charles Hetru, Ivica Letunic, Ngo Thi Hoa, Fotis C. Kafatos, Stéphanie Blandin, Liangbiao Zheng, Carolina Barillas-Mury, Mike A. Osta, Hans-Michael Müller, Jennifer Volz, Evgeny M. Zdobnov, Luis F. Moita, George Dimopoulos, Kristin Michel, Paul T. Brey, Laurent Troxler, Dina Vlachou, George K. Christophides, Susan M. Paskewitz, Ewan Birney, Alberto Danielli
Publikováno v:
Science, Vol. 298, No 5591 (2002) pp. 159-165
We have identified 242 Anopheles gambiae genes from 18 gene families implicated in innate immunity and have detected marked diversification relative to Drosophila melanogaster . Immune-related gene families involved in recognition, signal modulation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c06828989089607d228af6abe49fbfb
https://doi.org/10.1126/science.1077136
https://doi.org/10.1126/science.1077136
All metazoans are able to mount an innate immune response. Whereas invertebrate species rely solely on this type of defense, gnathostome vertebrates have developed, in addition, a sophisticated adaptive immune system centered on lymphocytes that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fa015536ce8db2e3cabb16f1efe72d2
https://doi.org/10.1128/9781555816872.ch1
https://doi.org/10.1128/9781555816872.ch1
Autor:
Timothy S. Heuer, Charles Hetru, Jean-Marc Reichhart, Laurent Troxler, Jules A. Hoffmann, Casey Kopczynski, Phil Irving, Marcia Belvin
Publikováno v:
Proceedings of the National Academy of Sciences. 98:15119-15124
Oligonucleotide DNA microarrays were used for a genome-wide analysis of immune-challenged Drosophila infected with Gram-positive or Gram-negative bacteria, or with fungi. Aside from the expression of an established set of immune defense genes, a sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc670603b5308cef5a2cecdd3b737b01
https://doi.org/10.1073/pnas.261573998
https://doi.org/10.1073/pnas.261573998