Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Charles H. Lin"'
Publikováno v:
European Journal of Biochemistry. 271:3693-3703
The interferon-β promoter has been studied extensively as a model system for combinatorial transcriptional regulation. In virus-infected cells the transcription factors ATF-2, c-Jun, interferon regulatory factor (IRF)-3, IRF-7 and NF-κB, and the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ca55ae8c28c6f0c73c8acb21e15a9ef
https://doi.org/10.1111/j.1432-1033.2004.04310.x
https://doi.org/10.1111/j.1432-1033.2004.04310.x
Publikováno v:
Journal of Biological Chemistry. 278:15495-15504
Interferon regulatory factor (IRF)-7 is activated in response to virus infection and stimulates the transcription of a set of cellular genes involved in host antiviral defense. The mechanism by which IRF-7 is activated and cooperates with other trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9578bdfe940a5fdd0e1cd474903e887e
https://doi.org/10.1074/jbc.m212940200
https://doi.org/10.1074/jbc.m212940200
Publikováno v:
European Journal of Biochemistry. 269:6142-6151
Virus infection results in the activation of a set of cellular genes involved in host antiviral defense. IRF-3 has been identified as a critical transcription factor in this process. The activation mechanism of IRF-3 is not fully elucidated, yet it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd2828845cce684bbe7fc3849444f81
https://doi.org/10.1046/j.1432-1033.2002.03330.x
https://doi.org/10.1046/j.1432-1033.2002.03330.x
Autor:
Tom Maniatis, Charles H. Lin, Gerhard Wagner, Ernest Fraenkel, Brian J. Hare, Stephen C. Harrison
Publikováno v:
Molecular Cell. 8(3):581-590
The transcriptional coactivators CBP and p300 are critical regulators of metazoan gene expression. They associate with many different DNA-bound transcription factors through small, conserved domains. We have identified a compactly folded 46 residue d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf55f7dfcec4578ab8a8d2dcbab547ea
Publikováno v:
Molecular and Cellular Biology. 20:4814-4825
Heterodimeric transcription factors, including the basic region-leucine zipper (bZIP) protein ATF-2-c-jun, are well-characterized components of an enhanceosome that mediates virus induction of the human beta interferon (IFN-beta) gene. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84255f862cbbb2a0bbc5ad6143987d32
https://doi.org/10.1128/mcb.20.13.4814-4825.2000
https://doi.org/10.1128/mcb.20.13.4814-4825.2000
Autor:
Lucienne V. Ronco, Tom Maniatis, Peter M. Howley, Marc G. Wathelet, Bhavin S. Parekh, Charles H. Lin
Publikováno v:
Molecular Cell. 1(4):507-518
We have identified a virus-activated factor (VAF) that binds to a regulatory element shared by different virus-inducible genes. We provide evidence that VAF contains two members of the interferon regulatory factor (IRF) family of transcriptional acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d7f9a798ad117db61124dcf5fdee8d
Autor:
Charles H. Lin, Tae Hoon Kim, Tom Maniatis, Tae Kyung Kim, James V. Falvo, Marc G. Wathelet, Bhavin S. Parekh
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 63:609-620
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25baf25fb5be7842423b98b85b0505f
https://doi.org/10.1101/sqb.1998.63.609
https://doi.org/10.1101/sqb.1998.63.609
Abstract 3607: An evaluation of NGS to identify gene fusions using RNA from FFPE solid tumor samples
Autor:
Tingting Du, Michael R. Rossi, Charles H. Lin, Taofee K. Owonikoko, Zhao Chen, Jennifer S. LoCoco, Gabriel Sica, Scott Newman, Brian Crain, Han-Yu Chuang, Snedecor June, Julianna Tdr Parks, Kathryn M. Stephens, Stewart G. Neill, Luo Byron, Debra Saxe, Matthew Friedenberg
Publikováno v:
Cancer Research. 76:3607-3607
Gene fusions have long been considered strong drivers of cellular transformation, making the accurate and precise assessment of these variants a necessity for any tumor profiling assay. Recent studies have indicated the utility of next-generation seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dec6aa2c6a96aff078d300ab8c2b299b
https://doi.org/10.1158/1538-7445.am2016-3607
https://doi.org/10.1158/1538-7445.am2016-3607
Publikováno v:
DNA and RNA Profiling in Human Blood ISBN: 9781934115930
Recent breakthroughs in multiplexed SNP (single nucleotide polymorphism) genotyping technology have enabled global mapping of the relationships between genetic variation and disease. Discoveries made by such whole-genome association studies often spu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::552164c8c0bf35416f5e0e99e9e107ff
https://doi.org/10.1007/978-1-59745-553-4_10
https://doi.org/10.1007/978-1-59745-553-4_10
Autor:
Anne E. Goldfeld, Peter K. Hwang, James V. Falvo, Dimitris Thanos, Tom Maniatis, Alla V. Tsytsykova, Charles H. Lin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(50)
The transcription factor NFATp integrates multiple signal transduction pathways through coordinate binding with basic-region leucine zipper (bZIP) proteins and other transcription factors. The NFATp monomer, even in the absence of its activation doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e264ee586797a2c113a0c59eb67d3504
https://pubmed.ncbi.nlm.nih.gov/19060202
https://pubmed.ncbi.nlm.nih.gov/19060202