Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Charles H Danan"'
Autor:
Louis R. Parham, Patrick A. Williams, Kay Katada, Shaneice K. Nettleford, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 439-451 (2024)
Background & Aims: The intestinal epithelium interfaces with a diverse milieu of luminal contents while maintaining robust digestive and barrier functions. Facultative intestinal stem cells are cells that survive tissue injury and divide to re-establ
Externí odkaz:
https://doaj.org/article/2d55833f363e489b8c29b533990b04ea
Autor:
Patrick A. Williams, Kaitlyn E. Naughton, Lauren A. Simon, Gloria E. Soto, Louis R. Parham, Xianghui Ma, Charles H. Danan, Weiming Hu, Elliot S. Friedman, Emily A. McMillan, Hritik Mehta, Madison A. Stoltz, Joshua Soto Ocaña, Joseph P. Zackular, Kyle Bittinger, Kelly A. Whelan, Tatiana A. Karakasheva, Kathryn E. Hamilton
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G354-G368
Calorie restriction is associated with enhanced intestinal regeneration after irradiation, but the requirement of autophagy for this process is not known. Our data support the premise that intestinal epithelial autophagy is required for the regenerat
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G91-G98
The profound complexity of the intestinal mucosa demands a spatial approach to the study of gut transcriptomics. Although single-cell RNA sequencing has revolutionized our ability to survey the diverse cell types of the intestine, knowledge of cell t
Autor:
Daniel Benhalevy, Sanjay K. Gupta, Charles H. Danan, Suman Ghosal, Hong-Wei Sun, Hinke G. Kazemier, Katrin Paeschke, Markus Hafner, Stefan A. Juranek
Publikováno v:
Cell Reports, Vol 18, Iss 12, Pp 2979-2990 (2017)
The CCHC-type zinc finger nucleic acid-binding protein (CNBP/ZNF9) is conserved in eukaryotes and is essential for embryonic development in mammals. It has been implicated in transcriptional, as well as post-transcriptional, gene regulation; however,
Externí odkaz:
https://doaj.org/article/87b8130288b44e5b8d7116b0b4c3da56
Autor:
Charles H. Danan, Kaitlyn E. Naughton, Katharina E. Hayer, Sangeevan Vellappan, Emily A. McMillan, Yusen Zhou, Rina Matsuda, Shaneice K. Nettleford, Kay Katada, Louis R. Parham, Xianghui Ma, Afrah Chowdhury, Benjamin J. Wilkins, Premal Shah, Matthew D. Weitzman, Kathryn E. Hamilton
Intestinal epithelial transit amplifying cells are essential stem progenitors required for intestinal homeostasis, but their rapid proliferation renders them vulnerable to DNA damage from radiation and chemotherapy. Despite their critical roles in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ba4e1d29349598369deb0938fa2c80
https://doi.org/10.1101/2023.04.06.535853
https://doi.org/10.1101/2023.04.06.535853
Autor:
Nicolette M Johnson, Louis R Parham, Jeeyoon Na, Keara E Monaghan, Hannah M Kolev, Alena Klochkova, Melissa S Kim, Charles H Danan, Zvi Cramer, Lauren A Simon, Kaitlyn E Naughton, Stephanie Adams‐Tzivelekidis, Yuhua Tian, Patrick A Williams, N Adrian Leu, Simone Sidoli, Kelly A Whelan, Ning Li, Christopher J Lengner, Kathryn E Hamilton
Publikováno v:
EMBO reports. 23(11)
The intestinal epithelium exhibits a rapid and efficient regenerative response to injury. Emerging evidence supports a model where plasticity of differentiated cells, particularly those in the secretory lineages, contributes to epithelial regeneratio
Autor:
Charles H. Danan, Katharina E. Hayer, Lauren A. Simon, Matthew D. Weitzman, Kathryn E. Hamilton
Publikováno v:
The FASEB Journal. 36
Autor:
Louis R. Parham, Patrick A. Williams, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Kay Katada, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton
Homeostatic tissue maintenance requires coordinated regulation of metabolic processes including macroautophagy/autophagy. Autophagy dysregulation underlies numerous human diseases. Our prior work revealed that the RNA binding protein IGF2BP1/IMP1 bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e81235c991a2c078f486f90778a5711
https://doi.org/10.1101/2022.02.28.482365
https://doi.org/10.1101/2022.02.28.482365
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618509
Methods in Molecular Biology ISBN: 9781493930661
Methods in Molecular Biology ISBN: 9781493930661
During post-transcriptional gene regulation (PTGR), RNA binding proteins (RBPs) interact with all classes of RNA to control RNA maturation, stability, transport, and translation. Here, we describe Photoactivatable-Ribonucleoside-Enhanced Cross linkin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0167bd4d12dacb44226e32c05d8a7de2
https://doi.org/10.1007/978-1-0716-1851-6_9
https://doi.org/10.1007/978-1-0716-1851-6_9
Autor:
Kim L, Gonzalez, Sarah E, Ratzel, Kendall H, Burks, Charles H, Danan, Jeanne M, Wages, Bethany K, Zolman, Bonnie, Bartel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(14)
ATPases have diverse cellular roles, including extracting proteins from membranes to maintain organellar function. The PEX1–PEX6 heterohexameric ATPases are thought to retrotranslocate PEX5 from the peroxisome membrane, and PEX1–PEX6 dysfunction