Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Charles H, Hubscher"'
Autor:
Daniel Medina-Aguiñaga, Robert F. Hoey, Natasha L. Wilkins, Beatrice Ugiliweneza, Jason Fell, Susan J. Harkema, Charles H. Hubscher
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Recent pre-clinical and clinical spinal cord epidural stimulation (scES) experiments specifically targeting the thoracolumbar and lumbosacral circuitries mediating lower urinary tract (LUT) function have shown improvements in storage, detrus
Externí odkaz:
https://doaj.org/article/38c35f99e0944758b6bb327bd112e2d9
Autor:
April N. Herrity, Sevda C. Aslan, Samineh Mesbah, Ricardo Siu, Karthik Kalvakuri, Beatrice Ugiliweneza, Ahmad Mohamed, Charles H. Hubscher, Susan J. Harkema
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Profound dysfunctional reorganization of spinal networks and extensive loss of functional continuity after spinal cord injury (SCI) has not precluded individuals from achieving coordinated voluntary activity and gaining multi-systemic autono
Externí odkaz:
https://doaj.org/article/b8b57357787d43d49db9fb13d284a7bc
Autor:
Jason H. Gumbel, Charles H. Hubscher
Publikováno v:
Neurotrauma Reports, Vol 3, Iss 1, Pp 190-198 (2022)
Spinal cord injury (SCI) significantly impacts many systems attributable to disrupted autonomic regulation of the body. Of these disruptions, excessive production/passage of urine (polyuria) has been understudied. Pre-clinical animal studies investig
Externí odkaz:
https://doaj.org/article/1eb72a42bb1849289eb9e083d7102d6d
Autor:
Robert F. Hoey, Daniel Medina-Aguiñaga, Fahmi Khalifa, Beatrice Ugiliweneza, Dengzhi Wang, Sharon Zdunowski, Jason Fell, Ahmed Naglah, Ayman S. El-Baz, April N. Herrity, Susan J. Harkema, Charles H. Hubscher
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Pre-clinical studies have shown that spinal cord epidural stimulation (scES) at the level of pelvic and pudendal nerve inputs/outputs (L5-S1) alters storage and/or emptying functions of both the bladder and bowel. The current mapping experim
Externí odkaz:
https://doaj.org/article/2945b87ac4844ba9bdf794cfc2c942df
Publikováno v:
Neurotrauma Reports, Vol 2, Iss 1, Pp 462-475 (2021)
Deficits in upper and lower urinary tract function, which include detrusor overactivity, urinary incontinence, detrusor-sphincter dyssynergia, and polyuria, are among the leading issues that arise after spinal cord injury (SCI) affecting quality of l
Externí odkaz:
https://doaj.org/article/3c22867c5b3741b183344757e0165f27
Autor:
Robert F. Hoey, Daniel Medina-Aguiñaga, Fahmi Khalifa, Beatrice Ugiliweneza, Sharon Zdunowski, Jason Fell, Ahmed Naglah, Ayman S. El-Baz, April N. Herrity, Susan J. Harkema, Charles H. Hubscher
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Abstract Spinal cord epidural stimulation (scES) mapping at L5-S1 was performed to identify parameters for bladder and bowel inhibition and/or contraction. Using spinally intact and chronic transected rats of both sexes in acute urethane-anesthetized
Externí odkaz:
https://doaj.org/article/69935db908644956bec5213faacd046d
Publikováno v:
Asian Journal of Andrology, Vol 23, Iss 1, Pp 30-35 (2021)
The ex-copula penile dorsiflexion reflex (PDFR) is an established measure of sexual dysfunction in male rat models of spinal cord injury. Although the PDFR after complete spinal transection is well described, information regarding the more clinically
Externí odkaz:
https://doaj.org/article/8584c97c62ab4154b58ba8eb228f98f8
Autor:
April N. Herrity, Sevda C. Aslan, Beatrice Ugiliweneza, Ahmad Z. Mohamed, Charles H. Hubscher, Susan J. Harkema
Publikováno v:
Frontiers in Systems Neuroscience, Vol 14 (2021)
Spinal cord injury (SCI) results in profound neurologic impairment with widespread deficits in sensorimotor and autonomic systems. Voluntary and autonomic control of bladder function is disrupted resulting in possible detrusor overactivity, low compl
Externí odkaz:
https://doaj.org/article/2067e2bad4834ba4b2a59c2fb9ac1cf2
Autor:
Daniel Medina‐Aguinaga, Robert F. Hoey, Alvaro Munoz, Moises Altamira‐Camacho, Jose L. Quintanar, Charles H. Hubscher
Publikováno v:
Physiological Reports, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract The objective of the current animal study was to investigate factors contributing to the different phases of the cystometrogram (CMG) in order to address disparities in research data reported in the current literature. Three experiments in 2
Externí odkaz:
https://doaj.org/article/0eaf1dbfce5840189171e9ebe945a8c6
Publikováno v:
The Journal of Spinal Cord Medicine. :1-7
Activity-based recovery training (ABRT) reverses spinal cord injury (SCI) induced polyuria and alterations of biomarkers involved with fluid balance, including expression levels of kidney vasopressin 2 receptors. However, void volumes do not return t