Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Charles H, Cook"'
Autor:
Noe B. Mercado, Jacqueline N. Real, Jacob Kaiserman, Eleni Panagioti, Charles H. Cook, Sean E. Lawler
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract Glioblastoma (GBM) is one of the deadliest brain cancers with a median survival of only 15 months. This poor prognosis has prompted exploration of novel therapeutic targets for GBM patients. Human cytomegalovirus (HCMV) has been implicated i
Externí odkaz:
https://doaj.org/article/018f7697d6444b4abc5f1b05d01732e2
Publikováno v:
Journal of Emergencies, Trauma and Shock, Vol 9, Iss 3, Pp 103-106 (2016)
Context: We noted a bimodal relationship between mortality and shock index (SI), the ratio of heart rate to systolic blood pressure. Aims: To determine if extremes of SI can predict mortality in trauma patients. Settings and Designs: Retrospective ev
Externí odkaz:
https://doaj.org/article/00894b1e96884f26a23d0e1bc759dc36
Publikováno v:
Viruses, Vol 6, Iss 4, Pp 1502-1524 (2014)
Interferons (IFNs) activate the first lines of defense against viruses, and promote innate and adaptive immune responses to viruses. We report that the immediate early 1 (IE1) protein of human cytomegalovirus (HCMV) disrupts signaling by IFNγ. The c
Externí odkaz:
https://doaj.org/article/12704c7251f24803b16ae4d7ac7c58ee
Autor:
David C Evans, Kendrick M Khoo, Andrei Radulescu, Charles H Cook, Anthony T Gerlach, Thomas J Papadimos, Steven M Steinberg, Stanislaw PA Stawicki, Daniel S Eiferman
Publikováno v:
Journal of Emergencies, Trauma and Shock, Vol 7, Iss 4, Pp 305-309 (2014)
Purpose: Trauma dogma dictates that the physiologic response to injury is blunted by beta-blockers and other cardiac medications. We sought to determine how the pre-injury cardiac medication profile influences admission physiology and post-injury out
Externí odkaz:
https://doaj.org/article/9b22ae4ef04b49fe98647109b1847fd6
Autor:
Savas Tsikis, Charles S. Parsons, Bonnie Butt, Stephen R. Odom, Charles H. Cook, Nisha Narula, Sayuri P. Jinadasa
Publikováno v:
The American Surgeon. 88:1137-1145
Background Though many trauma patients are on anticoagulation or antiplatelet therapy (AAT), there are few generalizable data on the risks for these patients. The purpose of this study was to analyze the impact of anticoagulation (AC) and antiplatele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6b22bc01ca8df1094de2264094087d
https://doi.org/10.1177/0003134821989043
https://doi.org/10.1177/0003134821989043
Autor:
Brendin R Beaulieu-Jones, Jayson Marwaha, Chris J Kennedy, Kortney Robinson, Aaron Fleishman, Danny Le, Charles H Cook, Larry Nathanson, Gabriel Brat
Publikováno v:
Journal of the American College of Surgeons. 235:S142-S143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::129585f62c9e01a47c666b210cd7ceaa
https://doi.org/10.1097/01.xcs.0000894060.76547.2f
https://doi.org/10.1097/01.xcs.0000894060.76547.2f
Autor:
Joanne Trgovcich, Michelle Kincaid, Alicia Thomas, Marion Griessl, Peter Zimmerman, Varun Dwivedi, Valerie Bergdall, Paul Klenerman, Charles H Cook
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167097 (2016)
Cytomegalovirus (CMV) has been shown to induce large populations of CD8 T-effector memory cells that unlike central memory persist in large quantities following infection, a phenomenon commonly termed "memory inflation". Although murine models to dat
Externí odkaz:
https://doaj.org/article/e60f78e315ab4ba0876ac49a87c89392
Autor:
Larry A. Nathanson, Elizabeth B. Habermann, Charles H. Cook, Aaron Fleishman, Sean M. Stokes, Lyen C. Huang, Gabriel A. Brat, Cornelius A. Thiels, Kortney A. Robinson, Mario Feranil, Sarah Duncan
Publikováno v:
Annals of Surgery. 275:e361-e365
Objective: We compare consensus recommendations for 5 surgical procedures to prospectively collected patient consumption data. To address local variation, we combined data from multiple hospitals across the country. Summary of background data One app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fc9dc7ec0635231077b32826f2fa01
https://doi.org/10.1097/sla.0000000000003986
https://doi.org/10.1097/sla.0000000000003986
Publikováno v:
Journal of virological methods. 301
Next Generation Sequencing allows for deep analysis of transcriptional activity in cells and tissues, however it is still a cost intensive method that demands well versed data handling. Reverse transcription quantitative PCR (RT-qPCR) is the most com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747be667bb600b4d1f7ddf16d54d3b84
https://pubmed.ncbi.nlm.nih.gov/34929204
https://pubmed.ncbi.nlm.nih.gov/34929204
Publikováno v:
Medical Microbiology and Immunology. 208:295-303
There is a decades old association between cytomegalovirus reactivation and sepsis in immune-competent hosts. Much has been learned about this relationship, which has been described as bidirectional, meaning that the virus incites and is incited by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7eb80e44ca1409e0eb092ea8227d4cf
https://doi.org/10.1007/s00430-019-00603-y
https://doi.org/10.1007/s00430-019-00603-y