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pro vyhledávání: '"Charles G. Kurland"'
Autor:
Ajith Harish, Charles G. Kurland
Publikováno v:
Biochimie. 138:137-155
A reliable phylogenetic reconstruction of the evolutionary history of contemporary species depends on a robust identification of the universal common ancestor (UCA) at the root of the Tree of Life (ToL). That root polarizes the tree so that the evolu
Publikováno v:
Genome Biology and Evolution
The evolutionary origins of viruses according to marker gene phylogenies, as well as their relationships to the ancestors of host cells remains unclear. In a recent article Nasir and Caetano-Anolles reported that their genome-scale phylogenetic analy
Autor:
Ajith Harish, Charles G. Kurland
Publikováno v:
Molecular Mechanisms of Microbial Evolution ISBN: 9783319690773
In 1998, on the brink of a great public effort that by now has delivered the sequences of thousands of genomes and has annotated these genomes by translating tens of thousands of 3D protein domain structures from their coding sequences, Ernst Mayr an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c3678794b342f6deed6c7897ff63311
https://doi.org/10.1007/978-3-319-69078-0_2
https://doi.org/10.1007/978-3-319-69078-0_2
Autor:
Ajith Harish, Charles G. Kurland
Publikováno v:
Biochimie. 119:205-208
Autor:
Ajith Harish, Charles G. Kurland
Publikováno v:
Biochimie. 119:284-302
In this introductory retrospective, evolution as viewed through gene trees is inspected through a lens compounded from its founding operational assumptions. The four assumptions of the gene tree culture that are singularly important to evolutionary i
Autor:
Ajith Harish, Charles G. Kurland
Publikováno v:
Journal of theoretical biology. 434
Lynn Sagan's conjecture (1967) that three of the fundamental organelles observed in eukaryote cells, specifically mitochondria, plastids and flagella were once free-living primitive (prokaryotic) cells was accepted after considerable opposition. Even
Autor:
Ajith Harish, Charles G. Kurland
Publikováno v:
Biochimie. 138
We reconstructed a global tree of life (ToL) with non-reversible and non-stationary models of genome evolution that root trees intrinsically. We implemented Bayesian model selection tests and compared the statistical support for four conflicting ToL
Reply to Caetano-Anollés et al. comment on 'Empirical genome evolution models root the tree of life'
Autor:
Ajith Harish, Charles G. Kurland
Publikováno v:
Biochimie. 149:137-138
We recently analyzed the robustness of competing evolution models developed to identify the root of the Tree of Life: 1) An empirical Sankoff parsimony (ESP) model (Harish and Kurland, 2017), which is a nonstationary and directional evolution model;
Autor:
Charles G. Kurland
Publikováno v:
BioEssays. 32:866-871
Modern cells present no signs of a putative prebiotic RNA world. However, RNA coding is not a sine qua non for the accumulation of catalytic polypeptides. Thus, cellular proteins spontaneously fold into active structures that are resistant to proteol
Publikováno v:
Molecular Microbiology. 75:1078-1089
Genes introduced by gene replacements and other types of horizontal gene transfer (HGT) represent a significant presence in many archaeal and eubacterial genomes. Most alien genes are likely to be neutral or deleterious upon arrival and their long-te