Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Charles G. Bailey"'
Autor:
Gerard J. Chu, Charles G. Bailey, Rajini Nagarajah, Sharon M. Sagnella, Stephen Adelstein, John E. J. Rasko
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Chimeric antigen receptor (CAR) T-cells have revolutionized the treatment of CD19- and B-cell maturation antigen-positive haematological malignancies. However, the effect of a CAR construct on the function of T-cells stimulated vi
Externí odkaz:
https://doaj.org/article/c567b9f811a84470a0eab063b6a318d5
Autor:
Tamara Treleaven, Matthew Zada, Rajini Nagarajah, Charles G. Bailey, John E. J. Rasko, Michael B. Morris, Margot L. Day
Publikováno v:
Cells, Vol 12, Iss 1, p 18 (2022)
L-proline (Pro) has previously been shown to support normal development of mouse embryos. Recently we have shown that Pro improves subsequent embryo development when added to fertilisation medium during in vitro fertilisation of mouse oocytes. The me
Externí odkaz:
https://doaj.org/article/5d18cc2b9ed44b3ea03a67edc9551eda
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background Growth factors, such as EGF, activate the PI3K/Akt/mTORC1 signalling pathway, which regulates a distinct program of protein synthesis leading to cell growth. This pathway relies on mTORC1 sensing sufficient levels of intracellular
Externí odkaz:
https://doaj.org/article/434dc0c6851742df8f7324f72d6605f2
Autor:
Megha Rajasekhar, Ulf Schmitz, Stephane Flamant, Justin J.-L. Wong, Charles G. Bailey, William Ritchie, Jeff Holst, John E. J. Rasko
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Myelopoiesis involves differentiation of hematopoietic stem cells to cellular populations that are restricted in their self-renewal capacity, beginning with the common myeloid progenitor (CMP) and leading to mature cells including monocytes
Externí odkaz:
https://doaj.org/article/5130f8e3f39c40e099172e258a4f2129
Autor:
Bijay P. Dhungel, Geoffray Monteuuis, Caroline Giardina, Mehdi S. Tabar, Yue Feng, Cynthia Metierre, Sarah Ho, Rajini Nagarajah, Angela R. M. Fontaine, Jaynish S. Shah, Divya Gokal, Charles G. Bailey, Ulf Schmitz, John E. J. Rasko
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12178 (2021)
Chimeric RNAs are often associated with chromosomal rearrangements in cancer. In addition, they are also widely detected in normal tissues, contributing to transcriptomic complexity. Despite their prevalence, little is known about the characteristics
Externí odkaz:
https://doaj.org/article/76580557ad97406c8cd6513f7e7d7f09
Autor:
Fiona H. X. Guan, Charles G. Bailey, Cynthia Metierre, Patrick O’Young, Dadi Gao, Teh Liane Khoo, Jeff Holst, John E. J. Rasko
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-17 (2017)
Abstract Background ELF2 (E74-like factor 2) also known as NERF (new Ets-related factor), a member of the Ets family of transcription factors, regulates genes important in B and T cell development, cell cycle progression, and angiogenesis. Conserved
Externí odkaz:
https://doaj.org/article/7b2473cba9a04a6ba0866c14b53fc6ad
Autor:
Ulf Schmitz, Jaynish S. Shah, Bijay P. Dhungel, Geoffray Monteuuis, Phuc-Loi Luu, Veronika Petrova, Cynthia Metierre, Shalima S. Nair, Charles G. Bailey, Verity A. Saunders, Ali G. Turhan, Deborah L. White, Susan Branford, Susan J. Clark, Timothy P. Hughes, Justin J.-L. Wong, John E.J. Rasko
Publikováno v:
Cancers, Vol 12, Iss 12, p 3738 (2020)
Vast transcriptomics and epigenomics changes are characteristic of human cancers, including leukaemia. At remission, we assume that these changes normalise so that omics-profiles resemble those of healthy individuals. However, an in-depth transcripto
Externí odkaz:
https://doaj.org/article/7f9c37c705da45f193de8536d3cea524
Autor:
Jane R. Engler, Andrew C.W. Zannettino, Charles G. Bailey, John E.J. Rasko, Timothy P. Hughes, Deborah L. White
Publikováno v:
Haematologica, Vol 96, Iss 2 (2011)
Background Despite the excellent responses to imatinib therapy observed in patients with chronic phase chronic myeloid leukemia, approximately 25% of patients display primary resistance or suboptimal response. The OCT-1 activity in mononuclear cells
Externí odkaz:
https://doaj.org/article/4f5807c0b6b5416398d8fb83bbf5d47b
Autor:
Jeff Holst, John E.J. Rasko, Colleen C. Nelson, Grant Buchanan, Stephen C. Hendy, Melanie L. Lehman, Vineet Minhas, Annora Thoeng, Jessamy Tiffen, Cynthia Ng, Charles G. Bailey, Qian Wang
PDF file - 1.5K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5044669b4304c59017cd4d001a67230b
https://doi.org/10.1158/0008-5472.22389840
https://doi.org/10.1158/0008-5472.22389840
Autor:
Jeff Holst, John E.J. Rasko, Colleen C. Nelson, Grant Buchanan, Stephen C. Hendy, Melanie L. Lehman, Vineet Minhas, Annora Thoeng, Jessamy Tiffen, Cynthia Ng, Charles G. Bailey, Qian Wang
PDF file - 141K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cf862b2b58318cd0667adcb2bdfd18
https://doi.org/10.1158/0008-5472.22389837.v1
https://doi.org/10.1158/0008-5472.22389837.v1