Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Charles G., Cranfield"'
Autor:
Edward York, Daniel A. McNaughton, Ariane Roseblade, Charles G. Cranfield, Philip A. Gale, Tristan Rawling
Publikováno v:
ACS Chemical Biology. 17:2065-2073
Targeting the cancer cell mitochondrion is a promising approach for developing novel anticancer agents. The experimental anticancer agent N,N'-bis(3,5-dichlorophenyl)urea (SR4) induces apoptotic cell death in several cancer cell lines by uncoupling m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c356f5831058f04675fb33c7b6b3a3
https://doi.org/10.1021/acschembio.1c00807
https://doi.org/10.1021/acschembio.1c00807
Autor:
Jacqueline White, Evelyne Deplazes, Beatriu Domingo Tafalla, Alvaro Garcia, Christopher Murphy, Charles G. Cranfield
Publikováno v:
Langmuir. 37:14026-14033
Calcium ions (Ca2+) play a fundamental role in membrane-associated physiological processes. Ca2+ can also significantly modulate the physicochemical properties of phospholipid bilayers, but whether this occurs at physiologically relevant concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636d26542fd79f4f1161a7a6967f59d1
https://doi.org/10.1021/acs.langmuir.1c02016
https://doi.org/10.1021/acs.langmuir.1c02016
Publikováno v:
International journal of molecular sciences. 24(1)
The Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9580850bc8ef2277972ec4f8a501edec
https://pubmed.ncbi.nlm.nih.gov/36613508
https://pubmed.ncbi.nlm.nih.gov/36613508
Publikováno v:
The Journal of Physical Chemistry Letters. 11:8152-8156
GALA is a 30-residue amphipathic peptide that self-assembles into multimeric transmembrane pores in a pH-dependent fashion. In this study, we characterize the size, multimeric structure, and cation selectivity of GALA pores in planar phospholipid bil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60286f4e472943c3efd095b5bdfc3917
https://doi.org/10.1021/acs.jpclett.0c02335
https://doi.org/10.1021/acs.jpclett.0c02335
Publikováno v:
The Journal of Physical Chemistry Letters. 11:6353-6358
Despite the central role of Na+ and K+ in physiological processes, it is still unclear whether they interact or alter the physical properties of simple zwitterionic phospholipid bilayers at physiol...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c40077f56916a1624828843081639cd
https://doi.org/10.1021/acs.jpclett.0c01479
https://doi.org/10.1021/acs.jpclett.0c01479
Autor:
Samira R. Aili, Matthew P. Padula, Alvaro Garcia, Axel Touchard, Christopher Murphy, Evelyne Deplazes, Graham M. Nicholson, Bruce Cornell, Upeksha Mirissa Lankage, Charles G. Cranfield
Publikováno v:
ACS Biomaterials Science and Engineering
ACS Biomaterials Science and Engineering, ACS, 2020, 6 (8), pp.4714-4721. ⟨10.1021/acsbiomaterials.0c00632⟩
ACS Biomaterials Science and Engineering, ACS, 2020, 6 (8), pp.4714-4721. ⟨10.1021/acsbiomaterials.0c00632⟩
International audience; Phospholipase-A (PLA) enzymes catalyze the hydrolysis of ester bonds in select glycerophospholipids. Sensors for rapidly measuring the PLA activity in biological samples have relevance in the study of venom compositions and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4c9114be61f3c0b971949ec00af834
https://doi.org/10.1021/acsbiomaterials.0c00632
https://doi.org/10.1021/acsbiomaterials.0c00632
Autor:
Ronald J. Clarke, Bogdan Lev, Milna Chennath, Toby W. Allen, Charles G. Cranfield, Emma-Lucille Blayney, Flemming Cornelius
Publikováno v:
Biophysical Journal. 122:529a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3b467afa12b2d7c168951298fa9f05b
https://doi.org/10.1016/j.bpj.2022.11.2807
https://doi.org/10.1016/j.bpj.2022.11.2807
Publikováno v:
Antibiotics, Vol 8, Iss 1, p 12 (2019)
This review identifies the ways in which tethered bilayer lipid membranes (tBLMs) can be used for the identification of the actions of antimicrobials against lipid bilayers. Much of the new research in this area has originated, or included researcher
Externí odkaz:
https://doaj.org/article/d73d2019b2584c69bebaa97093d29dce
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618424
Swept frequency electrical impedance spectroscopy (EIS) can be used in conjunction with tethered bilayer lipid membranes to monitor the membrane permeability of ions in real-time (Deplazes et al. J Phys Chem Lett 11:6353-6358, 2020). Conductance read
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3976ed0931fed21eb1b897b172ae0cb6
https://hdl.handle.net/10453/152994
https://hdl.handle.net/10453/152994
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2402
Swept frequency electrical impedance spectroscopy (EIS) can be used in conjunction with tethered bilayer lipid membranes to monitor the membrane permeability of ions in real-time (Deplazes et al. J Phys Chem Lett 11:6353-6358, 2020). Conductance read
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f49125070fe5f36c6e5ee263b1a343b8
https://pubmed.ncbi.nlm.nih.gov/34854037
https://pubmed.ncbi.nlm.nih.gov/34854037