Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Charles G Humiston"'
Autor:
J.M. Norris, J. J. Ballard, J.E. Beyer, J.F. Quast, C.E. Wade, Charles G Humiston, R.W. Schwetz
Publikováno v:
Toxicological Sciences. 3:55-62
The chronic toxicity and oncogenic potential of ingested vinylidene chloride (VDC) was evaluated in a 2-year study on Sprague-Dawley rats and the subchronic toxicity was evaluated in beagle dogs in a 97-day study. The vinylidene chloride was incorpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70215d9481d7170dbed67998d9a93ce0
https://doi.org/10.1093/toxsci/3.1.55
https://doi.org/10.1093/toxsci/3.1.55
Autor:
D.A. Dittenber, R.J. Kociba, J. J. Ballard, Charles G Humiston, D. G. Keyes, C.E. Wade, J.F. Quast, G. C. Jersey, B.A. Schwetz
Publikováno v:
American Industrial Hygiene Association Journal. 38:589-602
Lifetime ingestion by rats of 0.2 mg/kg/day of hexachlorobutadiene caused no discernible ill effects. Slight degrees of primarily renal toxicity occurred with 2 mg/kg/day; 20 mg/kg/day caused multiple toxic effects, including renal tubular neoplasms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eedd524edd0dc8f2dd6e380ae00877c
https://doi.org/10.1080/00028897708984403
https://doi.org/10.1080/00028897708984403
Autor:
D.A. Dittenber, D. G. Keyes, G. C. Jersey, R.J. Kociba, Charles G Humiston, C.E. Wade, J. J. Ballard, B.A. Schwetz, J.F. Quast
Publikováno v:
Environmental Health Perspectives
Hexachlorobutadiene (HCBD), while not produced commercially in the United States, may be encountered as an unwanted by-product of certain processes associated with the chlorination of hydrocarbons. Studies were conducted to assess the potential long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6386a2e40d9d0d57ac9b70366d09efe
https://doi.org/10.1289/ehp.772149
https://doi.org/10.1289/ehp.772149
Publikováno v:
Environmental Health Perspectives
Male and female Sprague-Dawley rats were exposed to vinylidene chloride (VDC) orally or by inhalation in 2-year toxicological studies. Interim results are included in this report. VDC was given in the drinking water at mean +/- S.D. concentrations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31240ad1fdbfd0c75e0d19d45614cd9b
https://doi.org/10.1289/ehp.772133
https://doi.org/10.1289/ehp.772133
Publikováno v:
Toxicology and Applied Pharmacology. 42:387-398
Hexachlorobutadiene (HCBD) is a by-product of certain processes associated with the chlorination of hydrocarbons. Very small amounts of HCBD may also be produced in chlorine cells. This study evaluated the effects of HCBD on reproduction in rats. Gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6f71d014122cc4c9c433bbf733ded7
https://doi.org/10.1016/0041-008x(77)90016-3
https://doi.org/10.1016/0041-008x(77)90016-3
Autor:
George J. Wright, Charles G Humiston
Publikováno v:
Toxicology and Applied Pharmacology. 10:467-480
A method for measuring cholinesterase activity has been presented; it combines the rapidity of automation with the accuracy of manometric procedures. The measured response is linear over a wide range and makes possible the accurate determination of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f92cde1e0abacf5896214682781e0df
https://doi.org/10.1016/0041-008x(67)90087-7
https://doi.org/10.1016/0041-008x(67)90087-7
Autor:
Herbert E. Carter, Charles G. Humiston
Publikováno v:
Journal of Biological Chemistry. 191:727-733
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e181a511f247f5736b7032676270868f
https://doi.org/10.1016/s0021-9258(18)55977-9
https://doi.org/10.1016/s0021-9258(18)55977-9
Autor:
S.D. Barnard, R.M. Carreon, R.A. Hummel, L.E. Frauson, D.G. Keyes, R.J. Kociba, D.A. Dittenber, R.P. Kalnins, Colin N. Park, J.E. Beyer, C.E. Wade, Charles G Humiston
Publikováno v:
Toxicology and applied pharmacology. 46(2)
Rats were maintained for 2 years on diets supplying 0.1, 0.01, and 0.001 μg of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)/kg/day. Analysis of these diets indicated 2200, 210, and 22 parts per trillion (ppt) of TCDD. Ingestion of 0.1 μg/kg/day cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a7b8200ff1918bea5df3a7e719e9c6
https://pubmed.ncbi.nlm.nih.gov/734660
https://pubmed.ncbi.nlm.nih.gov/734660
Publikováno v:
Pentachlorophenol ISBN: 9781461589501
Male and female Sprague-Dawley rats were maintained on diets containing pentachlorophenol (PCP), characterized by a low content of nonphenolic impurities, for up to 24 months. Pentachlorophenol (PCP) was not found to be carcinogenic when administered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7369558cd5007a73efc39a3b5ca5a9d
https://doi.org/10.1007/978-1-4615-8948-8_26
https://doi.org/10.1007/978-1-4615-8948-8_26
Publikováno v:
Toxicology and applied pharmacology. 50(2)
A three-generation reproduction study was conducted to evaluate the effects of chronic, low-level ingestion of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Sprague-Dawley rats were maintained continuously on diets providing dose levels of 0, 0.001, 0.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d323e96cd66729812522e294bea970de
https://pubmed.ncbi.nlm.nih.gov/505455
https://pubmed.ncbi.nlm.nih.gov/505455