Výsledky vyhledávání - "Charles F. Sing"

Akademický článek

Contribution of regulatory and structural variations in APOE to predicting dyslipidemia

Autor: Jari H. Stengård, Sharon L.R. Kardia, Sara C. Hamon, Ruth Frikke-Schmidt, Anne Tybjærg-Hansen, Veikko Salomaa, Eric Boerwinkle, Charles F. Sing

Publikováno v: Journal of Lipid Research, Vol 47, Iss 2, Pp 318-328 (2006)

The objective of this study was to evaluate 1) whether non single nucleotide polymorphisms-coding (non-cSNP) in the apolipoprotein E gene (APOE) identified by resequencing studies contribute to statistically explaining dyslipidemia if variations in t

Externí odkaz: https://doaj.org/article/43f0a37909e147dd8b9164ff82ef4da9

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Akademický článek

APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study

Autor: Kathy L.E. Klos, Sara Hamon, Andrew G. Clark, Eric Boerwinkle, Kiang Liu, Charles F. Sing

Publikováno v: Journal of Lipid Research, Vol 46, Iss 3, Pp 564-570 (2005)

Genetic variation in the apolipoprotein A-V gene (APOA5) has been associated with variation in plasma triglyceride (TG) levels in African American and white females and males older than 40 years and/or at increased risk of coronary artery disease. We

Externí odkaz: https://doaj.org/article/32ec7c20793c48e58cf91a0db9c5625e

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Akademický článek

Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations.

Autor: Li Ma, Ariel Brautbar, Eric Boerwinkle, Charles F Sing, Andrew G Clark, Alon Keinan

Publikováno v: PLoS Genetics, Vol 8, Iss 5, p e1002714 (2012)

Total cholesterol, low-density lipoprotein cholesterol, triglyceride, and high-density lipoprotein cholesterol (HDL-C) levels are among the most important risk factors for coronary artery disease. We tested for gene-gene interactions affecting the le

Externí odkaz: https://doaj.org/article/6cccbbf2450b4e53955c2f0625a3399f

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Akademický článek

Variation in the maternal corticotrophin releasing hormone-binding protein (CRH-BP) gene and birth weight in Blacks, Hispanics and Whites.

Autor: Pathik D Wadhwa, Hyagriv N Simhan, Sonja Entringer, Claudia Buss, Roger Smith, Calvin J Hobel, Naveed Farhana, Lawrence Shimmin, James E Hixson, Charles F Sing

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e43931 (2012)

Given the unique role of the corticotrophin-releasing hormone (CRH) system in human fetal development, the aim of our study was to estimate the association of birth weight with DNA sequence variation in three maternal genes involved in regulating CRH

Externí odkaz: https://doaj.org/article/17e7025ebaa9443e97c07eeb88c770c8

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Akademický článek

Long-range autocorrelations of CpG islands in the human genome.

Autor: Benjamin Koester, Thomas J Rea, Alan R Templeton, Alexander S Szalay, Charles F Sing

Publikováno v: PLoS ONE, Vol 7, Iss 1, p e29889 (2012)

In this paper, we use a statistical estimator developed in astrophysics to study the distribution and organization of features of the human genome. Using the human reference sequence we quantify the global distribution of CpG islands (CGI) in each ch

Externí odkaz: https://doaj.org/article/127ad1ec073047d6a3a76dde6f0132b8

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