Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Charles F. Huebner"'
Autor:
Frank H. Ebetino, Norbert Gruenfeld, Leslie J. Browne, Candido Gude, Charles F. Huebner, Andrew M. Yuan, James L. Stanton
Publikováno v:
Journal of Medicinal Chemistry. 26:1277-1282
The preparation of a series of 1-glutarylindoline-2(S)-carboxylic acid derivatives, 6a-v and 21a-c, is described. The above compounds were tested for inhibition of angiotensin converting enzyme. The structure-activity relationship of the series is al
Publikováno v:
Drug Development Research. 6:345-361
CGS 10078B is a potent orally effective antihypertensive agent with β-adrenergic antagonist as well as other vasodilatory mechanisms. In spontaneously hypertensive rats, CGS 10078B (3 and 30 mg/kg, p.o.) caused rapid and significant dose-related red
Publikováno v:
Journal of Biological Chemistry. 145:155-162
Autor:
Karl Paul Link, Charles F. Huebner
Publikováno v:
Journal of the American Chemical Society. 67:99-102
Publikováno v:
The Journal of Organic Chemistry. 27:4465-4469
Publikováno v:
Journal of the American Chemical Society. 77:469-472
Publikováno v:
Journal of the American Chemical Society. 65:2288-2291
Publikováno v:
Journal of the American Chemical Society. 66:906-909
Autor:
A. Furlenmeier, Robert Schwyzer, A. F. St. André, H. B. MacPhillamy, J. M. Mueller, L. Dorfman, R. Lucas, Charles F. Huebner, E. Schlittler
Publikováno v:
Helvetica Chimica Acta. 37:59-75
Reserpine, C33H40O9N2, has been isolated from Rauwolfia serpentina Benth. Reserpine is an ester alkaloid yielding reserpic acid, 3,4,5-trimethoxybenzoic acid and methanol on hydrolysis. Degradation products of reserpic acid make it likely that reserp
Publikováno v:
Journal of Biological Chemistry. 159:503-515