Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Charles F Craddock"'
Autor:
Vasiliki Symeonidou, Marlen Metzner, Batchimeg Usukhbayar, Aimee E. Jackson, Sonia Fox, Charles F. Craddock, Paresh Vyas
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 794-803 (2022)
Abstract Acute myeloid leukaemia is prevalent in older patients that are often ineligible for intensive chemotherapy and treatment options remain limited with azacitidine being at the forefront. Azacitidine has been used in the clinic for decades, ho
Externí odkaz:
https://doaj.org/article/0ec7692b03e049f3a63341778660afdb
Autor:
Paresh Vyas, Jamie D. Cavenagh, Michael Dennis, Shamyla Siddique, Richard J. Kelly, Srinivas P. Pillai, Mary Frances McMullin, Keith Wheatley, Louise Dudley, Sandeep Nagra, Manoj Raghavan, Angela Hamblin, Alison Kennedy, Natalia Garcia-Martin, Marlen Metzner, Corran Roberts, Emma Gbandi, Paul Ferguson, Lynn Swun Quek, Aimee E. Houlton, Charles F. Craddock
Table S3. Variants detected by NGS targeted re-sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cac8136a16ee1bad22e1c2d07a962d
https://doi.org/10.1158/1078-0432.22468974.v1
https://doi.org/10.1158/1078-0432.22468974.v1
Autor:
Paresh Vyas, Jamie D. Cavenagh, Michael Dennis, Shamyla Siddique, Richard J. Kelly, Srinivas P. Pillai, Mary Frances McMullin, Keith Wheatley, Louise Dudley, Sandeep Nagra, Manoj Raghavan, Angela Hamblin, Alison Kennedy, Natalia Garcia-Martin, Marlen Metzner, Corran Roberts, Emma Gbandi, Paul Ferguson, Lynn Swun Quek, Aimee E. Houlton, Charles F. Craddock
Table S1. Details for NGS amplicons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2349da5f2731fe9b5293126d52cd1ddb
https://doi.org/10.1158/1078-0432.22468977.v1
https://doi.org/10.1158/1078-0432.22468977.v1
Autor:
Paresh Vyas, Jamie D. Cavenagh, Michael Dennis, Shamyla Siddique, Richard J. Kelly, Srinivas P. Pillai, Mary Frances McMullin, Keith Wheatley, Louise Dudley, Sandeep Nagra, Manoj Raghavan, Angela Hamblin, Alison Kennedy, Natalia Garcia-Martin, Marlen Metzner, Corran Roberts, Emma Gbandi, Paul Ferguson, Lynn Swun Quek, Aimee E. Houlton, Charles F. Craddock
Table S2. Details of Exons covered Table S4. Details of antibodies/ streptavidin used Table S5. Summary of longitudinal progenitor LSC quantitation by FACS Table S6. Overview of toxicities Figure S1. Progenitor LSC FACS gating strategy Figure S2. Kap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4008f6bb20cdb6eb9a1403c23f11f16
https://doi.org/10.1158/1078-0432.22468971.v1
https://doi.org/10.1158/1078-0432.22468971.v1
Autor:
Paresh Vyas, Jamie D. Cavenagh, Michael Dennis, Shamyla Siddique, Richard J. Kelly, Srinivas P. Pillai, Mary Frances McMullin, Keith Wheatley, Louise Dudley, Sandeep Nagra, Manoj Raghavan, Angela Hamblin, Alison Kennedy, Natalia Garcia-Martin, Marlen Metzner, Corran Roberts, Emma Gbandi, Paul Ferguson, Lynn Swun Quek, Aimee E. Houlton, Charles F. Craddock
Purpose: Azacitidine (AZA) is a novel therapeutic option in older patients with acute myeloid leukemia (AML), but its rational utilization is compromised by the fact that neither the determinants of clinical response nor its mechanism of action are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0327fb5df6da2c1e7558e937576087
https://doi.org/10.1158/1078-0432.c.6527109
https://doi.org/10.1158/1078-0432.c.6527109
Autor:
Eolia Brissot, Myriam Labopin, Marielle M. Beckers, Gérard Socié, Alessandro Rambaldi, Liisa Volin, Jürgen Finke, Stig Lenhoff, Nicolaus Kröger, Gert J. Ossenkoppele, Charles F. Craddock, Ibrahim Yakoub-Agha, Günhan Gürman, Nigel H. Russell, Mahmoud Aljurf, Michael N. Potter, Armon Nagler, Oliver Ottmann, Jan J. Cornelissen, Jordi Esteve, Mohamad Mohty
Publikováno v:
Haematologica, Vol 100, Iss 3 (2015)
This study aimed to determine the impact of tyrosine kinase inhibitors given pre- and post-allogeneic stem cell transplantation on long-term outcome of patients allografted for Philadelphia chromosome-positive acute lymphoblastic leukemia. This retro
Externí odkaz:
https://doaj.org/article/9ad982de38d0479d80ddde912a519cbe
Autor:
Robert N. Lown, Sameer Tulpule, Nigel H. Russell, Charles F. Craddock, Rochelle Roest, J. Alejandro Madrigal, Bronwen E. Shaw
Publikováno v:
Haematologica, Vol 98, Iss 12 (2013)
Approximately 1 in 20 unrelated donors are asked to make a second donation of hematopoietic progenitor cells, the majority for the same patient. Anthony Nolan undertook a study of subsequent hematopoietic progenitor cell donations made by its donors
Externí odkaz:
https://doaj.org/article/235d232310484fe486216e486057fb1a
Autor:
Francesca A M Kinsella, Wayne Croft, Hayden Pearce, Charlotte F. Inman, Charles F Craddock, Jianmin Zuo, Ram Malladi, Sara Barbieri, Paul Moss
Publikováno v:
Transplantation and cellular therapy. 27(6)
Alemtuzumab is a CD52-specific lympho-depleting antibody. CD52− T cells emerge under alemtuzumab selection pressure. We sought to investigate the phenotype and function of the CD52− T cell fraction and related their presence to clinical outcome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b03409c0b9287890b2c61a00c5b668
https://pubmed.ncbi.nlm.nih.gov/33863699
https://pubmed.ncbi.nlm.nih.gov/33863699
Autor:
Luke Maggs, Y. L. Tracey Chan, Hayden Pearce, Paul Moss, Suzy Eldershaw, Jianmin Zuo, Charles F Craddock, Michael J. Griffiths, Jane Nunnick, Charlotte F. Inman, Sandeep Nagra, Ram Malladi, Francesca A M Kinsella
Transplantation is an effective treatment of many clinical disorders, but the mechanisms that regulate immunological tolerance are uncertain and remain central to improving patient outcome. Hemopoietic stem cell transplantation (SCT) often establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c1b46ae54f5064c86d5a37bb63054c
https://europepmc.org/articles/PMC6418492/
https://europepmc.org/articles/PMC6418492/
Autor:
Charles F. Craddock, Betty Nakamoto, Robert G. Andrews, Gregory V. Priestley, Thalia Papayannopoulou
Publikováno v:
Blood. 90:4779-4788
Although the use of cytokine-mobilized peripheral blood stem cells has gained a significant momentum in clinical transplantation, the mobilization schemes practiced are guided by a great deal of empiricism. The mechanism(s) by which cytokines or chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1769b8f65de70db6f3bb5d149e08c4ad
https://doi.org/10.1182/blood.v90.12.4779.4779_4779_4788
https://doi.org/10.1182/blood.v90.12.4779.4779_4779_4788