Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Charles F, Eisenbeis"'
Autor:
Sharon Wilks, Scot Sedlacek, Praveen K. Reddy, Jagathi D. Challagalla, Mary Ann K Allison, Joyce O'Shaughnessy, Charles F. Eisenbeis, Carlos A. Taboada, Yunfei Wang, Marcus A. Neubauer, Nicholas Koutrelakos, Sasha Vukelja, Cynthia Osborne, Lina Asmar, Frankie A. Holmes
Publikováno v:
Clinical Breast Cancer. 18:e89-e95
Background Hormonal therapies and single-agent sequential chemotherapeutic regimens are the standards of care for HER2 − metastatic breast cancer (MBC). However, treating patients with hormone-refractory and triple negative (TN) MBC remains challen
Autor:
Amy Banks, Pablo Garcia, Pierluigi Porcu, Lawrence D. Piro, Michael A. Caligiuri, Amy K. Ferketich, John P. Leonard, Don M. Benson, Lei Chen, Khuda D. Khan, Sandra Milan, Glenn C. Michelson, Christos Emmanouilides, John C. Byrd, Deborah Hurst, Charles F. Eisenbeis
Publikováno v:
Clinical Cancer Research. 12:7046-7053
Purpose: The incidence of non-Hodgkin's lymphoma (NHL), the fifth most common malignancy in the United States, has increased over 70% in the last 30 years. Fifty percent to 75% of patients with low-grade or follicular NHL respond to rituximab therapy
Autor:
Charles F. Eisenbeis, Donn C. Young, Amy Banks, John C. Byrd, T. S. Lin, Andrew P. Mone, Carolyn Cheney, Sara K. Guster, Susheela Tridandapani, Najma Mehter
Publikováno v:
Leukemia. 20:272-279
Alemtuzumab is a humanized IgG1 kappa antibody directed against CD52, a glycosyl-phosphatidylinositol linked cell-membrane protein of unknown function. Herein, we demonstrate that alemtuzumab promotes rapid death of chronic lymphocytic leukemia (CLL)
Autor:
Ronald P. Pelletier, Charles F. Eisenbeis, Sameek Roychowdhury, Michael A. Caligiuri, Amy K. Ferketich, Anne M. VanBuskirk, Julie Dierksheide, Robert A. Baiocchi
Publikováno v:
Blood. 105:1558-1565
Posttransplantation lymphoproliferative disorder (PTLD) is a devastating post-transplantation complication often associated with Epstein-Barr virus (EBV). Although the type and length of immunosuppression are risk factors, a patient's inherent immune
Autor:
William L. Marsh, Charles F. Eisenbeis, Robert A. Baiocchi, Gerard J. Nuovo, Sameek Roychowdhury, Elizabeth A. Davies, Srinivas Vourganti, Ronald P. Pelletier, Ronald M. Ferguson, Mitchell L. Henry, Michael A. Caligiuri, Amy K. Ferketich, Pierluigi Porcu
Publikováno v:
Blood. 100:2341-2348
Posttransplantation lymphoproliferative disorder (PTLD) is a life-threatening Epstein-Barr virus (EBV)–associated B-cell malignancy occurring in 1% to 2% of renal transplantation patients. Host- and PTLD-related factors determining the likelihood o
Publikováno v:
Genes & Development. 9:1377-1387
The immunoglobulin light-chain gene enhancers E kappa 3', E lambda 2-4, and E lambda 3-1 contain a conserved cell type-specific composite element essential for their activities. This element binds a B cell-specific heterodimeric protein complex that
Autor:
Michael Walker, Padma Nadella, Donn C. Young, Poongothai Sundaram, Mirela Anghelina, Gregory B. Lesinski, William E. Carson, Mario Sznol, Robin Parihar, Charles F. Eisenbeis, Jing Liu, Daniel Valentino
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(34)
PurposeTo evaluate the safety of sequentially administered recombinant (r) human (h) interleukin-12 (IL-12) and interferon alfa-2b (IFN-α-2b) in patients with advanced cancer and to determine the effects of endogenously produced IFN-γ on Janus kina
Autor:
Shannon Puhalla, Robert A. Baiocchi, John C. Byrd, Andrew P. Mone, Tamara Vukosavljevic, Amy Banks, Charles F. Eisenbeis, Susan P. Whitman, Julio Cruz, Michael A. Caligiuri, Pierluigi Porcu
Publikováno v:
Blood. 106(10)
Adult T-cell leukemia (ATL) is a highly chemoresistant and usually fatal T-cell malignancy due to the human T-cell lymphotropic virus-1 (HTLV-1). After chemotherapy failure, antiretrovirals and interferon-α (IFN-α) produce brief responses followed
Autor:
Bradley W. Blaser, Darshna Bhatt, Jim J. Xiao, Charles F. Eisenbeis, Srinivas Vourganti, Sameek Roychowdhury, Michael A. Caligiuri, Jason Chou, Mark R. Parthun, Robert A. Baiocchi, Ching-Shih Chen, Michael R. Grever, Chang Shi Chen, Amy K. Ferketich, Kenneth K. Chan, Aharon G. Freud
Publikováno v:
Journal of the National Cancer Institute. 96(19)
BACKGROUND Immune-compromised individuals are at increased risk for developing aggressive Epstein-Barr virus (EBV)-associated lymphoproliferative disorders after primary EBV infection or for reactivation of a preexisting latent EBV infection. We eval
Autor:
Charles F, Eisenbeis, Andrew, Grainger, Beth, Fischer, Robert A, Baiocchi, Lester, Carrodeguas, Sameek, Roychowdhury, Lei, Chen, Amy L, Banks, Thomas, Davis, Donn, Young, Nicole, Kelbick, Julie, Stephens, John C, Byrd, Michael R, Grever, Michael A, Caligiuri, Pierluigi, Porcu
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(18 Pt 1)
Cytokine-induced modulation of innate immunity is being explored to enhance the activity of monoclonal antibodies. Severe combined immunodeficient (SCID) mice engrafted with peripheral blood leukocytes (PBLs) from Epstein Barr virus-seropositive dono