Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Charles Esimone"'
Autor:
Ambada N. Georgia, Ntsama E. Claudine, Sake N. Carole, Ngu N. Loveline, Lissom Abel, Tchouangeu T. Flaurent, Sosso Martin, Alain Bopda Waffo, Malachy Okeke, Charles Esimone, Chae Gyu Park, Colizzi Vittorio, Etoa François-Xavier, Nchinda W. Godwin
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract We previously demonstrated that the overall number of regulatory T (Treg) cells decrease proportionately with helper CD4+ T cells and their frequencies increase in antiretroviral therapy (ART)-naive human immunodeficiency virus type-1 (HIV-1
Externí odkaz:
https://doaj.org/article/8e4cf8c0fab444f3963de1511ed75ead
Autor:
Moses Ikegbunam, Johnson A. Ojo, Kossiwa Kokou, Ugonna Morikwe, Chukwuemeka Nworu, Chibuzo Uba, Charles Esimone, Thirumalaisamy P. Velavan, Olusola Ojurongbe
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-6 (2021)
Abstract Background The occurrence of artemisinin resistance (ART)-associated polymorphism of Plasmodium falciparum K13-propeller (pfk13) gene before and after the introduction of artemisinin-based combination therapy (ACT) in two regions of Nigeria
Externí odkaz:
https://doaj.org/article/8a7192ce401c432e9b03a3673e625fba
Autor:
Chika Ejikeugwu, Okoro Nworie, Morteza Saki, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji, Chika Ezeador, Emmanuel Nwakaeze, Peter Eze, Eniola Oni, Chidiebere Obi, Ifeanyichukwu Iroha, Charles Esimone, Michael U. Adikwu
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Gram-negative bacteria (GNB) including Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae represent the most relevant reservoir of resistance genes such as metallo-β-lactamase (MBL) and AmpC genes that give them
Externí odkaz:
https://doaj.org/article/de952b78901b4094bf453e76b0dca2e1
Autor:
Kenneth Ngwoke, Nwalusiuka Tochukwu, Chinechem Ekwealor, Valerie Nwankwo, Uju Obi-Okafor, Chisom Izundu, Festus B. C. Okoye, Charles Esimone, Peter Proksch, Chen Situ
Publikováno v:
Pharmaceutical Biology, Vol 57, Iss 1, Pp 310-317 (2019)
Context: Nigerian soil fungi population is unexplored. It is hypothesized that they harbour new bioactive chemicals. This hypothesis is based on the large percentage of currently approved medicines that originated from soil-inhabiting micro-organisms
Externí odkaz:
https://doaj.org/article/604531ed779e477a886ef94697f289a6
Autor:
Chika Ejikeugwu, Charles Esimone, Ifeanyichukwu Iroha, Peter Eze, Malachy Ugwu, Michael Adikwu
Publikováno v:
Journal of Pure and Applied Microbiology, Vol 12, Iss 4, Pp 1877-1885 (2018)
The non-hospital environment particularly poultry farms and abattoirs are fast becoming reservoir channels for the transmission of antibiotic resistant bacteria including those that produce metallo beta-lactamases (MBLs). Foodproducing animal’s ha
Externí odkaz:
https://doaj.org/article/a21cd210c80244ee9b93ad66cf9315bd
Autor:
Carissa Duru, Grace Olanipekun, Vivian Odili, Nicholas Kocmich, Amy Rezac, Theresa O Ajose, Nubwa Medugu, Dominic Umoru, Chukwuma Onuchukwu, Huda Munir, Binta Wudil Jibir, Zubaida Farouk, Safiya Gambo, Fatimah Hassan-Hanga, Rasaq Olaosebikan, Bernard Ebruke, Charles Esimone, Stephen Obaro
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0230037 (2020)
BackgroundBacteremia is a leading cause of mortality in developing countries, however, etiologic evaluation is infrequent and empiric antibiotic use not evidence-based. Here, we evaluated the patterns of ESBL resistance in children enrolled into a su
Externí odkaz:
https://doaj.org/article/f04b55a318e2486f84b8a8cc76ab9ec5
Autor:
Chimezie Anyakora, Yetunde Oni, Uchenna Ezedinachi, Adebola Adekoya, Ibrahim Ali, Charles Nwachukwu, Charles Esimone, Victor Abiola, Jude Nwokike
Publikováno v:
BMC Pregnancy and Childbirth, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background The high level of maternal mortality and morbidity as a result of complications due to childbirth is unacceptable. The impact of quality medicines in the management of these complications cannot be overemphasized. Most of those me
Externí odkaz:
https://doaj.org/article/90dff12b292d4ee6923d20df51764580
Publikováno v:
Pharmaceutics, Vol 6, Iss 2, Pp 268-280 (2014)
There is need to develop reproducible methods and experimental models for screening mucosal irritation and toxicity for drugs and pharmaceutical excipients. The aim of this study was to validate Calu-3 cell line as a model for screening respiratory i
Externí odkaz:
https://doaj.org/article/9e2783ce8da14285a70702498d318b1f
Autor:
Perpetua A. Ekwealor, Malachy C. Ugwu, Ifeanyi Ezeobi, George Amalukwe, Belinda C. Ugwu, Ugochukwu Okezie, Catherine Stanley, Charles Esimone
Publikováno v:
International Journal of Microbiology, Vol 2016 (2016)
Urinary tract infections (UTIs) account for one of the major reasons for most hospital visits and the determination of the antimicrobial susceptibility patterns of uropathogens will help to guide physicians on the best choice of antibiotics to recomm
Externí odkaz:
https://doaj.org/article/57c73ce6ed854312b7cbe1b6ee75350b
Publikováno v:
Journal of Medical Sciences. 23:1-6