Výsledky vyhledávání - "Charles Emmanuel Jebaraj Walter"

Akademický článek

A microRNA binding site polymorphism in the 3′ UTR region of VEGF-A gene modifies colorectal cancer risk based on ethnicity: a meta-analysis

Autor: Sai Sushmitha Kontham, Charles Emmanuel Jebaraj Walter, Zioni Sangeetha Shankaran, Arvind Ramanathan, Nirmala Karuppasamy, Thanka Johnson

Publikováno v: Journal of the Egyptian National Cancer Institute, Vol 34, Iss 1, Pp 1-12 (2022)

Abstract Background Vascular endothelial growth factor A (VEGF-A) plays an integral role in angiogenesis by contributing to growth, development, and metastasis of solid tumors. Recently, a single-nucleotide polymorphism +936C/T located in the VEGF-A

Externí odkaz: https://doaj.org/article/068d32d5a441424ab95044f2b57ac14c

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Akademický článek

Investigating the role of microRNA-27a gene polymorphisms and its interactive effect with risk factors in gastrointestinal cancers

Autor: Zioni Sangeetha Shankaran, Charles Emmanuel Jebaraj Walter, Nandini Prakash, Kotteeswaran Ramachandiran, George Priya Doss C, Thanka Johnson

Publikováno v: Heliyon, Vol 6, Iss 3, Pp e03565- (2020)

Gastrointestinal (GI) cancers are known to have a high incidence worldwide and require an early diagnosis to successfully treat them, providing higher survival rates and better quality of life for the patients. MicroRNA-27a is a well-known oncogene t

Externí odkaz: https://doaj.org/article/a7ddf17bf71d45079cf3830b0f7ee338

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Akademický článek

Differential expression of NF-κB heterodimer RelA/p50 in human urothelial carcinoma

Autor: Sankari Durairajan, Charles Emmanuel Jebaraj Walter, Mary Divya Samuel, Dinesh Palani, Dicky John Davis G, George Priya Doss C, Sneha Pasupati, Thanka Johnson

Publikováno v: PeerJ, Vol 6, p e5563 (2018)

Background Urothelial carcinoma (UC) is the fifth most common malignancy that accounts for 5% of all cancers. Diagnostic markers that predict UC progressions are inadequate. NF-κB contributes towards disease progression upon constitutive activation

Externí odkaz: https://doaj.org/article/088a368c797e428aaf6f33876e4e38ed

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Selective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD Peptide

Autor: George Priya Doss C, Kalaiselvi Periyandavan, Thanka Johnson, Hannah Rachel Vasanthi A, Charles Emmanuel Jebaraj Walter, Sankari Durairajan, G. Dicky John Davis, Gayathri Thiruvengadam

Publikováno v: American Journal of Biochemistry and Biotechnology. 16:184-198

Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23ce1b4bbd17bb7f9f65b517d071a4be
https://doi.org/10.3844/ajbbsp.2020.184.198

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An Effective and Viable DNA Extraction Protocol for FFPE Tissues and its Effect on Downstream Molecular Application

Autor: Sai Sushmitha Kontham, Manjula Raju, Zioni Sangeetha Shankaran, Chinambedu Dandapani Mohanapriya, Charles Emmanuel Jebaraj Walter, Nirmala Karuppasamy, Thanka Johnson

Publikováno v: American Journal of Biochemistry and Biotechnology. 16:148-161

Archival Formalin-Fixed Paraffin-Embedded (FFPE) tissues are a readily available source of DNA for retrospective studies including genetic predisposition. FFPE tissues present significant challenges for extraction of pure genomic DNA in adequate amou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a359331c6d671d39fb593aab89d20dff
https://doi.org/10.3844/ajbbsp.2020.148.161

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Investigating the role of microRNA-27a gene polymorphisms and its interactive effect with risk factors in gastrointestinal cancers

Autor: Kotteeswaran Ramachandiran, Nandini Prakash, Zioni Sangeetha Shankaran, George Priya Doss C, Charles Emmanuel Jebaraj Walter, Thanka Johnson

Publikováno v: Heliyon, Vol 6, Iss 3, Pp e03565-(2020)
Heliyon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68b4306c1be50bfbd701bf857263492
http://www.sciencedirect.com/science/article/pii/S2405844020304102

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Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene

Autor: S, Udhaya Kumar, D, Thirumal Kumar, Pinky D, Mandal, Srivarshini, Sankar, Rishin, Haldar, Balu, Kamaraj, Charles Emmanuel Jebaraj, Walter, R, Siva, C, George Priya Doss, Hatem, Zayed

Publikováno v: Advances in protein chemistry and structural biology. 120

Sjögren-Larsson syndrome (SLS) is an autoimmune disorder inherited in an autosomal recessive pattern. To date, 80 missense mutations have been identified in association with the Aldehyde Dehydrogenase 3 Family Member A2 (ALDH3A2) gene causing SLS. D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::023edfaa84f3a7662e6f14d774ba3e6a
https://pubmed.ncbi.nlm.nih.gov/32085885

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Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene

Autor: Charles Emmanuel Jebaraj Walter, Balu Kamaraj, Hatem Zayed, Ramamoorthy Siva, C. George Priya Doss, S. Udhaya Kumar, D Thirumal Kumar, Rishin Haldar, Pinky D Mandal, Srivarshini Sankar

Publikováno v: Advances in Protein Chemistry and Structural Biology ISBN: 9780128213223

Sjogren–Larsson syndrome (SLS) is an autoimmune disorder inherited in an autosomal recessive pattern. To date, 80 missense mutations have been identified in association with the Aldehyde Dehydrogenase 3 Family Member A2 (ALDH3A2) gene causing SLS.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ded98c1ff602ffba6e117b82f4b61bb5
https://doi.org/10.1016/bs.apcsb.2019.11.004

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microRNA-146a gene polymorphism alters human colorectal cancer susceptibility and influences the expression of its target genes in toll-like receptor (TLR) pathway

Autor: Sivakumar Selvaraj, Zioni Sangeetha Shankaran, Mohanapriya Chinambedu Dandapani, Arvind Ramanathan, Thanka Johnson, Sai Sushmitha Kontham, Charles Emmanuel Jebaraj Walter

Publikováno v: Meta Gene. 24:100654

Gastrointestinal (GI) cancers are among the prime causes for cancer deaths worldwide demanding competent methods for prediction and diagnosis. MiR-146a, a key modulator of immunity and inflammation, harbors a single nucleotide polymorphism (SNP) rs29

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7cf76580e6443e04cd62664242b18094
https://doi.org/10.1016/j.mgene.2020.100654

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