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pro vyhledávání: '"Charles E. Rogler"'
Metastasis is a multistep process that involves the deregulation of oncogenes and tumor suppressors beyond changes required for primary tumor formation. RHOB is known to have tumor suppressor activity, and its knockdown is associated with more aggres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327c863ebe93910282616187dc91339d
https://doi.org/10.1158/1541-7786.c.6542070
https://doi.org/10.1158/1541-7786.c.6542070
Supplementary Data from Overexpression of miR-21 Promotes an In vitro Metastatic Phenotype by Targeting the Tumor Suppressor RHOB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fced6e170ef5ff8d183e94c295418f
https://doi.org/10.1158/1541-7786.22518681.v1
https://doi.org/10.1158/1541-7786.22518681.v1
Publikováno v:
BioTechniques, Vol 41, Iss 1, Pp 59-63 (2006)
A number of natural microRNA (miRNA) hairpins have been found in clusters of multiple identical or different copies, suggesting that effects of miRNAs can be enhanced and multiple genes can be regulated together by encoding multiple miRNA hairpins in
Externí odkaz:
https://doaj.org/article/614c63e77ba546378c7d7c7be816a861
Publikováno v:
Gene Expr
MicroRNAs (miRNAs) regulate cell fate selection and cellular differentiation. miRNAs of the miR23b polycistron (miR-23b, miR-27b, and miR-24) target components of the TGF-β signaling pathway and affect murine bile ductular and hepatocyte cell fate s
Autor:
Leslie E. Rogler, Remon Bebawee, Sanjeev Gupta, Joe S. Matarlo, Nicole Pattamanuch, Joseph Locker, Charles E. Rogler
Recent investigations have reported many markers associated with human liver stem/progenitor cells, “oval cells,” and identified “niches” in diseased livers where stem cells occur. However, there has remained a need to identify entire lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381e81f879eb0f71796bf7cd2f41bf92
https://europepmc.org/articles/PMC5256199/
https://europepmc.org/articles/PMC5256199/
Autor:
Pablo Landgraf, Erin Connolly, Thomas Tuschl, Tatyana Tchaikovskaya, Leslie E. Rogler, Margherita Melegari, Betty L. Slagle, Mihaela Zavolan, Bud C. Tennant, Charles E. Rogler
Publikováno v:
The American Journal of Pathology. 173:856-864
Alterations in microRNA (miRNA) expression in both human and animal models have been linked to many forms of cancer. Such miRNAs, which act directly as repressors of gene expression, have been found to frequently reside in fragile sites and genomic r
Publikováno v:
Hepatology. 46:1971-1978
Recent studies have shown a pluripotential nature of stem cells that were previously thought to be committed to specific lineages. HBC-3 cells are a clonal fetal murine hepatoblast cell line derived from an e9.5 murine embryo, and these cells can be
Publikováno v:
BioTechniques. 41:59-63
A number of natural microRNA (miRNA) hairpins have been found in clusters of multiple identical or different copies, suggesting that effects of miRNAs can be enhanced and multiple genes can be regulated together by encoding multiple miRNA hairpins in
Autor:
Hans Will, Heimer Greten, Maura Dandri, Martin R. Burda, Joerg Petersen, Alexander Bürkle, David M. Zuckerman, Charles E. Rogler
Publikováno v:
Hepatology. 35:217-223
Chronic infection with hepatitis B virus (HBV) is associated with an increased risk for the development of cirrhosis and hepatocellular carcinoma (HCC). Although clonal HBV DNA integrations are detected in nearly all HCCs the role of these integratio
Autor:
Charles E. Rogler, Joseph Rahimzadeh, Luigi D. Notarangelo, Remon Bebawee, Brian Kosmyna, Silvia Giliani, Leslie E. Rogler, Eric E. Bouhassira, Paul Frenette, Katrina M. Kutchko, David Moskowitz, Jayanta Roy-Chowdhury, Alain Laederach
Post-transcriptional processing of some long non-coding RNAs (lncRNAs) reveals that they are a source of miRNAs. We show that the 268-nt non-coding RNA component of mitochondrial RNA processing endoribonuclease, (RNase MRP), is the source of at least
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe0def74a327a8fe49dd01b2fd3ef57
http://hdl.handle.net/11379/453792
http://hdl.handle.net/11379/453792