Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Charles E. Dann"'
Autor:
Liang Yin, Vladimira Dragnea, George Feldman, Loubna A. Hammad, Jonathan A. Karty, Charles E. Dann, Carl E. Bauer
Publikováno v:
mBio, Vol 4, Iss 5 (2013)
ABSTRACT The DNA binding activity of the photosystem-specific repressor PpsR is known to be repressed by the antirepressor AppA. AppA contains a blue-light-absorbing BLUF domain and a heme-binding SCHIC domain that controls the interaction of AppA wi
Externí odkaz:
https://doaj.org/article/98ea41444d3d44cfaedaf3ecea57476e
Autor:
Nian Tong, Jennifer Wong-Roushar, Adrianne Wallace-Povirk, Yesha Shah, Morgan C. Nyman, Jade M. Katinas, Mathew Schneider, Carrie O’Connor, Xun Bao, Seongho Kim, Jing Li, Zhanjun Hou, Larry H. Matherly, Charles E. Dann, Aleem Gangjee
Publikováno v:
ACS Pharmacology & Translational Science. 6:748-770
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c2d99f0e56cb14cc8298ab6d6766d24
https://doi.org/10.1021/acsptsci.3c00020
https://doi.org/10.1021/acsptsci.3c00020
Autor:
Larry H. Matherly, Aleem Gangjee, Charles E. Dann, Zhanjun Hou, Jing Li, Joshua D. Rabinowitz, Lisa Polin, Maik Hüttemann, Seongho Kim, Juiwanna Kushner, Kathryn White, Sijana H. Dzinic, Carrie O'Connor, Adrianne Wallace-Povirk, Jenney Liu, Josephine Frühauf, Xun Bao, Changwen Ning, Arpit Doshi, Md. Junayed Nayeen, Jennifer Wong-Roushar, Jade M. Katinas, Gregory S. Ducker, Khushbu Shah, Aamod S. Dekhne
Supplementary Figure S1 shows in vitro antiproliferative activity and targeted pathways of previously reported AICARFTase and GARFTase inhibitors. Supplementary Figure S2 shows docking of AGF291, AGF320, and AGF347 (along with 5-formyl-THF) in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f58160726ffe67fe411c78ec2698b22
https://doi.org/10.1158/1535-7163.22505523.v1
https://doi.org/10.1158/1535-7163.22505523.v1
Autor:
Aamod S. Dekhne, Khushbu Shah, Gregory S. Ducker, Jade M. Katinas, Jennifer Wong-Roushar, Md. Junayed Nayeen, Arpit Doshi, Changwen Ning, Xun Bao, Josephine Frühauf, Jenney Liu, Adrianne Wallace-Povirk, Carrie O'Connor, Sijana H. Dzinic, Kathryn White, Juiwanna Kushner, Seongho Kim, Maik Hüttemann, Lisa Polin, Joshua D. Rabinowitz, Jing Li, Zhanjun Hou, Charles E. Dann, Aleem Gangjee, Larry H. Matherly
Publikováno v:
Molecular Cancer Therapeutics. 22:287-287
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77add014c1f088eaf12406ee9ad8e4d9
https://doi.org/10.1158/1535-7163.mct-22-0766
https://doi.org/10.1158/1535-7163.mct-22-0766
Publikováno v:
J Bacteriol
Bis-(3′-5′)-cyclic-dimeric GMP (c-di-GMP) is an important bacterial regulatory signaling molecule affecting biofilm formation, toxin production, motility, and virulence. The genome of Bacillus anthracis, the causative agent of anthrax, is predict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbb59a2def1d0a5e15d405643d1c51f
https://doi.org/10.1128/jb.00135-21
https://doi.org/10.1128/jb.00135-21
Autor:
Aleem Gangjee, Charles E. Dann, Gloria E. Garcia, Adrianne Wallace-Povirk, Larry H. Matherly, Nian Tong, Xilin Zhou, Jennifer Wong-Roushar, Jing Li, Zhanjun Hou, Carrie O'Connor, Seongho Kim, Xun Bao
Publikováno v:
Bioorg Med Chem
We discovered 6-substituted thieno[2,3-d]pyrimidine compounds (3-9) with 3-4 bridge carbons and side-chain thiophene or furan rings for dual targeting one-carbon (C1) metabolism in folate receptor- (FR) expressing cancers. Synthesis involved nine ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06805dd8b5fa2c09c783ca204a7abbbd
https://europepmc.org/articles/PMC8058616/
https://europepmc.org/articles/PMC8058616/
Publikováno v:
Journal of the American Society for Mass Spectrometry. 29:455-462
Sulfotyrosine and phosphotyrosine are two post-translational modifications present in higher eukaryotes. A simple and direct mass spectrometry method to distinguish between these modifications is crucial to advance our understanding of the sulfoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f25fb7079f9531987c8e09717380f72
https://doi.org/10.1007/s13361-017-1854-1
https://doi.org/10.1007/s13361-017-1854-1
Publikováno v:
Proceedings of the National Academy of Sciences. 114:13537-13542
Stator elements consisting of MotA4MotB2 complexes are anchored to the cell wall, extend through the cell membrane, and interact with FliG in the cytoplasmic C ring rotor of the flagellum. The cytoplasmic loop of MotA undergoes proton-driven conforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07126b5742a9d9fe085dfe0adf87db5b
https://doi.org/10.1073/pnas.1716231114
https://doi.org/10.1073/pnas.1716231114
Autor:
Jennifer Wong-Roushar, Aamod Dekhne, Charles E. Dann, Lisa Polin, Xun Bao, Seongho Kim, Jade M. Katinas, Adrianne Wallace-Povirk, Jose Cardiel Nunez, Md. Junayed Nayeen, Khushbu Shah, Zhanjun Hou, Aleem Gangjee, Carrie O'Connor, Jing Li, Larry Matherly
Publikováno v:
Cancer Research. 81:2348-2348
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. Though most patients initially respond to platinum-based therapy, the likelihood of disease reoccurrence is nearly 100%. Thus, new tumor-selective therapies for EOC are urgent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c590b449a67250dbda800df6bc929bdd
https://doi.org/10.1158/1538-7445.am2021-2348
https://doi.org/10.1158/1538-7445.am2021-2348
Autor:
Lisa Polin, Khushbu Shah, Zhanjun Hou, Arpit Doshi, Josephine Frühauf, Md. Junayed Nayeen, Kathryn White, Gregory S. Ducker, Jade M. Katinas, Seongho Kim, Larry H. Matherly, Changwen Ning, Adrianne Wallace-Povirk, Jing Li, Juiwanna Kushner, Maik Hüttemann, Jennifer Wong-Roushar, Carrie O'Connor, Jenney Liu, Xun Bao, Charles E. Dann, Sijana H. Dzinic, Aleem Gangjee, Joshua D. Rabinowitz, Aamod Dekhne
Folate-dependent one-carbon (C1) metabolism is compartmentalized into the mitochondria and cytosol and supports cell growth through nucleotide and amino acid biosynthesis. Mitochondrial C1 metabolism, including serine hydroxymethyltransferase (SHMT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae91497edf2a8770b4c5f8bc543f115
https://europepmc.org/articles/PMC6774887/
https://europepmc.org/articles/PMC6774887/