Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Charles E Murry"'
Autor:
Jill J Weyers, Jagadambika J Gunaje, Benjamin Van Biber, Amy Martinson, Hans Reinecke, William M Mahoney, Stephen M Schwartz, Timothy C Cox, Charles E Murry
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227780 (2020)
The engraftment of human stem cell-derived cardiomyocytes (hSC-CMs) is a promising treatment for remuscularizing the heart wall post-infarction, but it is plagued by low survival of transplanted cells. We hypothesize that this low survival rate is du
Externí odkaz:
https://doaj.org/article/e7136b4a79474dcb936ef5c772492ed3
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126259 (2015)
BackgroundMaternal smoking is a risk factor for low birth weight and other adverse developmental outcomes.ObjectiveWe sought to determine the impact of standard tobacco cigarettes and e-cigarettes on heart development in vitro and in vivo.MethodsZebr
Externí odkaz:
https://doaj.org/article/69d517d86a3a494693fd388fcf240caf
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131446 (2015)
Cardiac tissue engineering is a promising approach to provide large-scale tissues for transplantation to regenerate the heart after ischemic injury, however, integration with the host myocardium will be required to achieve electromechanical benefits.
Externí odkaz:
https://doaj.org/article/36d05422cf0c4f38afb23ca7044cfffc
Autor:
Jennifer I. Bennett, Mary O'Kelly Boit, Nicole E. Gregorio, Fan Zhang, Ryan D. Kibler, Jack W. Hoye, Olivia Prado, Peter B. Rapp, Charles E. Murry, Kelly R. Stevens, Cole A. DeForest
Publikováno v:
Advanced Science, Vol 11, Iss 24, Pp n/a-n/a (2024)
Abstract While direct cell transplantation holds great promise in treating many debilitating diseases, poor cell survival and engraftment following injection have limited effective clinical translation. Though injectable biomaterials offer protection
Externí odkaz:
https://doaj.org/article/fec70b04cd484a0d9a328989585eeeb5
Autor:
Ena Ray Banerjee, Michael A Laflamme, Thalia Papayannopoulou, Michael Kahn, Charles E Murry, William R Henderson
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33165 (2012)
Our aim was to differentiate human (h) embryonic stem (ES) cells into lung epithelial lineage-specific cells [i.e., alveolar epithelial type I (AEI) and type II (AEII) cells and Clara cells] as the first step in the development of cell-based strategi
Externí odkaz:
https://doaj.org/article/b7684b37f16243c9aa0ad3c5067f927e
Autor:
Jay A Gantz, Nathan J Palpant, Robert E Welikson, Stephen D Hauschka, Charles E Murry, Michael A Laflamme
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46971 (2012)
The differentiation of pluripotent stem cells involves transition through a series of specific cell states. To understand these cell fate decisions, the field needs improved genetic tools for the labeling, lineage tracing and selection of specific ce
Externí odkaz:
https://doaj.org/article/f9d56ffe70674db7a8231b3e54a8e37d
Autor:
Jonathan L Golob, Roshan M Kumar, Matthew G Guenther, Lil M Pabon, Gabriel A Pratt, Jeanne F Loring, Louise C Laurent, Richard A Young, Charles E Murry
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22416 (2011)
A surprising portion of both mammalian and Drosophila genomes are transcriptionally paused, undergoing initiation without elongation. We tested the hypothesis that transcriptional pausing is an obligate transition state between definitive activation
Externí odkaz:
https://doaj.org/article/28fad1b380e745e5aa28bac1c92d98f1
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11134 (2010)
Wnt/beta-catenin signaling is an important regulator of differentiation and morphogenesis that can also control stem cell fates. Our group has developed an efficient protocol to generate cardiomyocytes from human embryonic stem (ES) cells via inducti
Externí odkaz:
https://doaj.org/article/e536470824d54784afade1576f5ad104
Autor:
Ketaki N Mhatre, Jason D Murray, Galina Flint, Timothy S. McMillen, Gerhard Weber, Majid Shakeri, An-Yue Tu, Sonette Steczina, Robert Weiss, David J. Marcinek, Charles E Murry, Daniel Raftery, Rong Tian, Farid Moussavi-Harami, Michael Regnier
Publikováno v:
Journal of Molecular and Cellular Cardiology. 175:1-12
Hallmark features of systolic heart failure are reduced contractility and impaired metabolic flexibility of the myocardium. Cardiomyocytes (CMs) with elevated deoxy ATP (dATP) via overexpression of ribonucleotide reductase (RNR) enzyme robustly impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1360cb36ea43830e5cbf3890687c20f4
https://doi.org/10.1016/j.yjmcc.2022.11.010
https://doi.org/10.1016/j.yjmcc.2022.11.010
Autor:
Elaheh Karbassi, Charles E. Murry
Publikováno v:
Circulation. 145(18)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3724ca7d6b2dbc9539f69e55f0c667e8
https://pubmed.ncbi.nlm.nih.gov/35089805
https://pubmed.ncbi.nlm.nih.gov/35089805