Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Charles E Bane"'
Autor:
Jeffrey B Kaplan, Kevin D Mlynek, Hashani Hettiarachchi, Yonas A Alamneh, Lionel Biggemann, Daniel V Zurawski, Chad C Black, Charles E Bane, Robert K Kim, Mark S Granick
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205526 (2018)
Staphylococcal extracellular polymeric substances (EPS) such as extracellular DNA (eDNA) and poly-N-acetylglucosamine surface polysaccharide (PNAG) mediate numerous virulence traits including host colonization and antimicrobial resistance. Previous s
Externí odkaz:
https://doaj.org/article/0a6e3a1ad6de45fe852d4bcbf8971cd5
Autor:
Charles E Bane, Ivan Ivanov, Anton Matafonov, Kelli L Boyd, Qiufang Cheng, Edward R Sherwood, Erik I Tucker, Stephen T Smiley, Owen J T McCarty, Andras Gruber, David Gailani
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152968 (2016)
Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP) suggested that the protease factor XIa contributed
Externí odkaz:
https://doaj.org/article/15e4234e34084d13b6001a61916bc58a
Autor:
Roland A. Cooper, Susan E. Leed, Qiang Zeng, Kevin A. Reynolds, Lacy Gaynor-Ohnstad, Lisa Xie, Hsiuling Lin, Jason C. Sousa, Jianbing Mu, Heather Gaona, Raul Olmeda, Martin J. Smilkstein, Brett R. Bayles, Brittney Potter, Michael K. Riscoe, Richard J. Sciotti, Papireddy Kancharla, Yuexin Li, Brian Vesely, Sovitj Pou, Sean R. Marcsisin, Chau Vuong, Qigui Li, Brandon S. Pybus, Lisa Read, Victor Melendez, Norma Roncal, Thu Lan Luong, Diana Caridha, Chad C. Black, Rozalia A. Dodean, Jing Zhang, Kirk Butler, Patrick K Tumwebaze, Charles E. Bane, Philip J. Rosenthal, Stephanie A Rasmussen, Mara Kreishman-Deitrick, Jane Xu Kelly, Frida G. Ceja, Ping Zhang, Christina K. Nolan
Publikováno v:
J Med Chem
The global impact of malaria remains staggering despite extensive efforts to eradicate the disease. With increasing drug resistance and the absence of a clinically available vaccine, there is an urgent need for novel, affordable, and safe drugs for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a8e0165bf6ef34369b69238cb312a6
https://doi.org/10.1021/acs.jmedchem.0c00539
https://doi.org/10.1021/acs.jmedchem.0c00539
Autor:
Alex G. Waterson, Gary A. Sulikowski, Edward J. Metzger, Alec Walter, Richard J. Sciotti, Sydney L. Drury, Scott B Joseph, Chad C. Black, E. Duco Jansen, Eric P. Skaar, Mary T. Macdonald, Mingfeng Bai, Brendan F. Dutter, Clare L. Laut, Meng Su, James E. Crowe, Charles E. Bane, Anderson R. Miller, Monique R. Bennett, Ian M. Romaine, Bingwen Jing
Publikováno v:
Antimicrob Agents Chemother
Staphylococcus aureus is a serious threat to public health due to the rise of antibiotic resistance in this organism, which can prolong or exacerbate skin and soft tissue infections (SSTIs). Methicillin-resistant S. aureus is a Gram-positive bacteriu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4805f6e3f7488a96401cd5c661279b2d
https://doi.org/10.1128/aac.00919-21
https://doi.org/10.1128/aac.00919-21
Autor:
Yuexin Li, Kirk Butler, Brittney Potter, Qigui Li, Papireddy Kancharla, Roland A. Cooper, Thu Lan Luong, Heather Gaona, Jing Zhang, Richard J. Sciotti, Brian Vesely, Chau Vuong, Qiang Zeng, Sean R. Marcsisin, Michael K. Riscoe, Diana Caridha, Jason C. Sousa, Rolf W. Winter, Norma Roncal, Christina K. Nolan, Lisa Read, Rozalia A. Dodean, Lisa Xie, Lacy Gaynor-Ohnstad, Stephanie J. Huezo, Susan E. Leed, Hsiuling Lin, John C. Tan, Martin J. Smilkstein, Stephanie A Rasmussen, Jane Xu Kelly, Ping Zhang, Chad C. Black, Melissa T. Stephens, Mara Kreishman-Deitrick, Raul Olmeda, Victor Melendez, Sovitj Pou, Charles E. Bane
Malaria remains one of the deadliest diseases in the world today. Novel chemoprophylactic and chemotherapeutic antimalarials are needed to support the renewed eradication agenda. We have discovered a novel antimalarial acridone chemotype with dual-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351c0f6f16032d54883ac7a5e8be555b
https://europepmc.org/articles/PMC6822569/
https://europepmc.org/articles/PMC6822569/
Autor:
Owen J. T. McCarty, Andras Gruber, Qiufang Cheng, Erik I. Tucker, David Gailani, Charles E. Bane, Stephen T. Smiley, Edward R. Sherwood, Kelli L. Boyd, Anton Matafonov, Ivan B. Ivanov
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152968 (2016)
PLoS ONE
PLoS ONE
Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP) suggested that the protease factor XIa contributed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d80b6b477b16bf2f0de5df44abb36b0
http://europepmc.org/articles/PMC4821616?pdf=render
http://europepmc.org/articles/PMC4821616?pdf=render
Autor:
Yonas Alamneh, Hashani Hettiarachchi, Jeffrey B. Kaplan, Kevin D. Mlynek, Mark S. Granick, Charles E. Bane, Lionel Biggemann, Chad C. Black, Daniel V. Zurawski, Robert K. Kim
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205526 (2018)
PLoS ONE, Vol 13, Iss 10, p e0205526 (2018)
Staphylococcal extracellular polymeric substances (EPS) such as extracellular DNA (eDNA) and poly-N-acetylglucosamine surface polysaccharide (PNAG) mediate numerous virulence traits including host colonization and antimicrobial resistance. Previous s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bd53e00f45b8b1279977475ae41dc7
https://doi.org/10.1371/journal.pone.0205526
https://doi.org/10.1371/journal.pone.0205526
The most commonly used anticoagulants produce therapeutic antithrombotic effects either by inhibiting thrombin or factor Xa, or by lowering the plasma levels of the precursors of these key enzymes, prothrombin and factor X. These drugs do not disting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de636437d31295eadf79ba9ad6b1f8ec
https://europepmc.org/articles/PMC4516614/
https://europepmc.org/articles/PMC4516614/
Autor:
Charles E. Bane, David Gailani
Publikováno v:
Drug discovery today. 19(9)
Anticoagulants currently used in clinical practice to treat thromboembolic disorders are effective but increase the risk of severe bleeding because they target proteins that are essential for normal coagulation (hemostasis). Drugs with better safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56adad72cf6e116b39853e1163fc8af5
https://pubmed.ncbi.nlm.nih.gov/24886766
https://pubmed.ncbi.nlm.nih.gov/24886766
Publikováno v:
Hemostasis and Thrombosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::787360e4f9fee65dd6d98eabcf507c5f
https://doi.org/10.1002/9781118833391.ch6
https://doi.org/10.1002/9781118833391.ch6