Zobrazeno 1 - 10
of 445
pro vyhledávání: '"Charles E Alpers"'
Autor:
Mark A Little, Bahjat Al-Ani, Shuyu Ren, Hamad Al-Nuaimi, Maurilo Leite, Charles E Alpers, Caroline O Savage, Jeremy S Duffield
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28626 (2012)
Evidence is lacking for direct pathogenicity of human anti-proteinase-3 (PR3) antibodies in development of systemic vasculitis and granulomatosis with polyangiitis (GPA, Wegener's granulomatosis). Progress in study of these antibodies in rodents has
Externí odkaz:
https://doaj.org/article/0a52be606b1d451992c8fe286a7dc156
Autor:
Peter V Hauser, Jeffrey W Pippin, Cora Kaiser, Ronald D Krofft, Paul T Brinkkoetter, Kelly L Hudkins, Dontscho Kerjaschki, Jochen Reiser, Charles E Alpers, Stuart J Shankland
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9463 (2010)
Podocytes are injured in several glomerular diseases. To alter gene expression specifically in podocytes in vivo, we took advantage of their active endocytotic machinery and developed a method for the targeted delivery of small interfering ribonuclei
Externí odkaz:
https://doaj.org/article/f95cf1681a414500b4878d0db0e6aeb6
Autor:
Jonathan Barratt, Brad Rovin, Muh Geot Wong, Charles E. Alpers, Stewart Bieler, Ping He, Jula Inrig, Radko Komers, Hiddo J.L. Heerspink, Alex Mercer, Irene L. Noronha, Jai Radhakrishnan, Michelle N. Rheault, William Rote, Howard Trachtman, Hernán Trimarchi, Vlado Perkovic
Publikováno v:
Kidney International Reports, Vol 8, Iss 5, Pp 1043-1056 (2023)
Introduction: Sparsentan is a novel single-molecule dual endothelin angiotensin receptor antagonist with hemodynamic and anti-inflammatory properties and is not an immunosuppressant. The ongoing phase 3 PROTECT trial examines sparsentan in adults wit
Externí odkaz:
https://doaj.org/article/25a866cd50534c7d82716666703db077
Autor:
Mark P. Keller, Kelly L. Hudkins, Anath Shalev, Sushant Bhatnagar, Melkam A. Kebede, Matthew J. Merrins, Dawn Belt Davis, Charles E. Alpers, Michelle E. Kimple, Alan D. Attie
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107036- (2023)
Summary: Human and mouse genetics have delivered numerous diabetogenic loci, but it is mainly through the use of animal models that the pathophysiological basis for their contribution to diabetes has been investigated. More than 20 years ago, we sere
Externí odkaz:
https://doaj.org/article/2a0d513bf5f14082a8f6d638bd1a6e49
Autor:
Hannah J. Lomax-Browne, Nicholas R. Medjeral-Thomas, Sean J. Barbour, Jack Gisby, Heedeok Han, Andrew S. Bomback, Fernando C. Fervenza, Thomas H. Cairns, Richard Szydlo, Sven-Jean Tan, Stephen D. Marks, Aoife M. Waters, Gerald B. Appel, Vivette D. D’Agati, Sanjeev Sethi, Cynthia C. Nast, Ingeborg Bajema, Charles E. Alpers, Agnes B. Fogo, Christoph Licht, Fadi Fakhouri, Daniel C. Cattran, James E. Peters, H. Terence Cook, Matthew C. Pickering
Publikováno v:
Clin J Am Soc Nephrol
Clinical Journal of the American Society of Nephrology, 17(7), 994-1007. AMER SOC NEPHROLOGY
Clinical Journal of the American Society of Nephrology, 17(7), 994-1007. AMER SOC NEPHROLOGY
Background and objectives: C3 glomerulopathy and idiopathic Ig-associated membranoproliferative GN are kidney diseases characterized by abnormal glomerular complement C3 deposition. These conditions are heterogeneous in outcome, but approximately 50%
Publikováno v:
American Journal of Kidney Diseases. 80:119-131
The kidney biopsy is an essential tool for diagnosis of many kidney diseases. Obtaining an adequate biopsy sample with appropriate allocation for various studies is essential. Nephrologists should understand key lesions and their interpretation becau
Autor:
Rajasree Menon, Andrew S. Bomback, Blue B. Lake, Christy Stutzke, Stephanie M. Grewenow, Steven Menez, Vivette D. D’Agati, Sanjay Jain, Richard Knight, Stewart H. Lecker, Isaac Stillman, Steve Bogen, Laurence H. Beck, Sushrut Waikar, Gearoid M. McMahon, Astrid Weins, Mia R. Colona, Nir Hacohen, Paul J. Hoover, Mark Aulisio, William S. Bush, Dana C. Crawford, John O'toole, Emilio Poggio, John Sedor, Leslie Cooperman, Stacey Jolly, Leal Herlitz, Jane Nguyen, Agustin Gonzalez-Vicente, Ellen Palmer, Dianna Sendrey, Carissa Vinovskis, Petter M. Bjornstad, Paul Appelbaum, Jonathan M. Barasch, Vivette D. D'Agati, Krzysztof Kiryluk, Karla Mehl, Pietro A. Canetta, Ning Shang, Olivia Balderes, Satoru Kudose, Shweta Bansal, Theodore Alexandrov, Helmut Rennke, Tarek M. El-Achkar, Yinghua Cheng, Pierre C. Dagher, Michael T. Eadon, Kenneth W. Dunn, Katherine J. Kelly, Timothy A. Sutton, Daria Barwinska, Michael J. Ferkowicz, Seth Winfree, Sharon Bledsoe, Marcelino Rivera, James C. Williams, Ricardo Melo Ferreira, Chirag R. Parikh, Celia P. Corona-Villalobos, Avi Rosenberg, Sylvia E. Rosas, Neil Roy, Mark Williams, Evren U. Azeloglu, Cijang He, Ravi Iyengar, Jens Hansen, Yuguang Xiong, Brad Rovin, Samir Parikh, John P. Shapiro, Christopher R. Anderton, Ljiljana Pasa-Tolic, Dusan Velickovic, Jessica Lukowski, George Oliver, Joseph Ardayfio, Jack Bebiak, Keith Brown, Catherine E. Campbell, John Saul, Anna Shpigel, Robert Koewler, Taneisha Campbell, Lynda Hayashi, Nichole Jefferson, Glenda V. Roberts, Roy Pinkeney, Olga Troyanskaya, Rachel Sealfon, Katherine R. Tuttle, Yury Goltsev, Kun Zhang, Zoltan G. Laszik, Garry Nolan, Patrick Boada, Minnie Sarwal, Tara Sigdel, Paul J. Lee, Rita R. Alloway, E. Steve Woodle, Heather Ascani, Ulysses G.J. Balis, Jeffrey B. Hodgin, Matthias Kretzler, Chrysta Lienczewski, Laura H. Mariani, Becky Steck, Yougqun He, Edgar Otto, Jennifer Schaub, Victoria M. Blanc, Sean Eddy, Ninive C. Conser, Jinghui Luo, Paul M. Palevsky, Matthew Rosengart, John A. Kellum, Daniel E. Hall, Parmjeet Randhawa, Mitchell Tublin, Raghavan Murugan, Michele M. Elder, James Winters, Charles E. Alpers, Kristina N. Blank, Jonas Carson, Ian H. De Boer, Ashveena L. Dighe, Jonathan Himmelfarb, Sean D. Mooney, Stuart Shankland, Kayleen Williams, Christopher Park, Frederick Dowd, Robyn L. McClelland, Stephen Daniel, Andrew N. Hoofnagle, Adam Wilcox, Kumar Sharma, Manjeri Venkatachalam, Guanshi Zhang, Annapurna Pamreddy, Hongping Ye, Richard Montellano, Robert D. Toto, Miguel Vazquez, Simon C. Lee, R. Tyler Miller, Orson W. Moe, Jose Torrealba, Nancy Wang, Asra Kermani, Kamalanathan Sambandam, Harold Park, S. Susan Hedayati, Christopher Y. Lu, Anitha Vijayan, Joseph P. Gaut, Dennis Moledina, Francis P. Wilson, Ugochukwu Ugwuowo, Tanima Arora
Publikováno v:
Kidney Int
Autor:
Kelly D. Smith, David K. Prince, Kammi J. Henriksen, Roberto F. Nicosia, Charles E. Alpers, Shreeram Akilesh
Publikováno v:
Kidney International. 101:1017-1026
Collapsing glomerulopathy is a histologically distinct variant of focal and segmental glomerulosclerosis that presents with heavy proteinuria and portends a poor prognosis. Collapsing glomerulopathy can be triggered by viral infections such as HIV or
Autor:
Jiten, Patel, Jose R, Torrealba, Emilio D, Poggio, Jack, Bebiak, Charles E, Alpers, Stephanie M, Grewenow, Robert D, Toto, Michael T, Eadon
Publikováno v:
Clin J Am Soc Nephrol
The Kidney Precision Medicine Project (KPMP) seeks to establish a molecular atlas of the kidney in health and disease and improve our understanding of the molecular drivers of CKD and AKI. Herein, we describe the case of a 66-year-old woman with CKD
Autor:
Nicole K. Andeen, Shahad Abdulameer, Vivek Charu, Jonathan E. Zuckerman, Megan Troxell, Neeraja Kambham, Charles E. Alpers, Behzad Najafian, Roberto F. Nicosia, Kelly D. Smith, Vanderlene L. Kung, Rupali S. Avasare, Anusha Vallurupalli, J. Ashley Jefferson, Douglas Hecox, Leah Swetnam, Michifumi Yamashita, Mercury Lin, Mei Lin Bissonnette, Shreeram Akilesh, Jean Hou
Publikováno v:
Kidney International Reports. 7:568-579
There are limited reports on kidney biopsy findings in patients with mantle cell lymphoma (MCL).We initiated a multi-institutional, retrospective review of kidney biopsy findings in patients with active and treated MCL.A total of 30 patients with MCL