Zobrazeno 1 - 10
of 571
pro vyhledávání: '"Charles E, Wood"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Formalin fixation of biological specimens damages nucleic acids and limits their use in genomic analyses. Previously, we showed that RNA isolation with an organocatalyst (2-amino-5-methylphenyl phosphonic acid, used to speed up reversal of f
Externí odkaz:
https://doaj.org/article/c82f8591c92b4bb0a366519a2cd4a31f
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 883-894 (2022)
Formalin-fixed paraffin-embedded (FFPE) samples are the only remaining biological archive for many toxicological and clinical studies, yet their use in genomics has been limited due to nucleic acid damage from formalin fixation. Older FFPE samples wi
Externí odkaz:
https://doaj.org/article/abd933fa85be4600a08e1d6386fa3df4
Autor:
Kevin Yu, Michelle Rodriguez, Zubin Paul, Elizabeth Gordon, Tongjun Gu, Kelly Rice, Eric W. Triplett, Maureen Keller-Wood, Charles E. Wood
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The fetus develops in a privileged environment, as the placenta serves as both a gateway for nutrients and a barrier for pathogen transfer to the fetus. Regardless, recent evidence suggests the presence of bacterial DNA in both placenta and
Externí odkaz:
https://doaj.org/article/73ba9a1734ec4955b6a3e0f1853352b8
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 805-815 (2020)
MicroRNAs (miRNAs) are short non-coding RNA species that play key roles in post-transcriptional regulation of gene expression. MiRNAs also serve as a promising source of early biomarkers for different environmental exposures and health effects, altho
Externí odkaz:
https://doaj.org/article/a9271998c08d4068b9fb687ebf508ef9
Autor:
Miguel A. Zarate, Michelle D. Rodriguez, Eileen I. Chang, Jordan T. Russell, Thomas J. Arndt, Elaine M. Richards, Beronica A. Ocasio, Eva Aranda, Elizabeth M. Gordon, Kevin Yu, Josef Neu, Maureen Keller-Wood, Eric W. Triplett, Charles E. Wood
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Herein we describe an association between activation of inflammatory pathways following transient hypoxia and the appearance of the multidrug resistant bacteria Staphylococcus simulans in the fetal brain. Reduction of maternal arterial oxyge
Externí odkaz:
https://doaj.org/article/3cfd4a433f0f4938841b31318171a1dc
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
In utero treatment with glucocorticoids have been suggested to reprogram postnatal cardiovascular function and stress responsiveness. However, little is known about the effects of prenatal exposure to the natural corticosteroid, cortisol, on postnata
Externí odkaz:
https://doaj.org/article/373c6c9330244e1dbbb4db0d895230ed
Autor:
Kevin Yu, Michelle D Rodriguez, Zubin Paul, Elizabeth Gordon, Kelly Rice, Eric W Triplett, Maureen Keller-Wood, Charles E Wood
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217211 (2019)
Fetal development is thought to proceed in a sterile environment. Recent reports of the presence of bacterial DNA in human placenta, the transfer of live bacteria from mother to fetus after hypoxia in the pregnant sheep, and the presence of bacteria
Externí odkaz:
https://doaj.org/article/7f85dd203ef840b39c009c152b3e3bff
Autor:
Eileen I. Chang, Miguel A. Zarate, Thomas J. Arndt, Elaine M. Richards, Maria B. Rabaglino, Maureen Keller-Wood, Charles E. Wood
Publikováno v:
Frontiers in Physiology, Vol 9 (2019)
The physiological response to hypoxia in the fetus has been extensively studied with regard to redistribution of fetal combined ventricular output and sparing of oxygen delivery to fetal brain and heart. Previously, we have shown that the fetal brain
Externí odkaz:
https://doaj.org/article/e1c8dd0644064bfaac50d4dd4f3859d5
Autor:
Zigui Chen, Rob DeSalle, Mark Schiffman, Rolando Herrero, Charles E Wood, Julio C Ruiz, Gary M Clifford, Paul K S Chan, Robert D Burk
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007352 (2018)
Recent discoveries on the origins of modern humans from multiple archaic hominin populations and the diversity of human papillomaviruses (HPVs) suggest a complex scenario of virus-host evolution. To evaluate the origin of HPV pathogenesis, we estimat
Externí odkaz:
https://doaj.org/article/d293a12722f4405bbb8f13ce95e9e1ea
Autor:
J. Mark Cline, Adrian A. Franke, Janet A. Tooze, Thomas C. Register, Cynthia J. Willson, Cynthia J. Lees, Charles E. Wood, Fitriya N. Dewi
PDF file - 115K, Epithelial cell proliferation in the mammary tissue of cynomolgus macaque was not affected by soy treatment across pubertal transition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf8073605b7f260f80fc7b99cf01370
https://doi.org/10.1158/1940-6207.22525607.v1
https://doi.org/10.1158/1940-6207.22525607.v1