Zobrazeno 1 - 10
of 674
pro vyhledávání: '"Charles E, Wade"'
Autor:
Sarah Lombardo, Ram Nirula, Elliott R Haut, Scott Brakenridge, Brandon Bruns, Charles E Wade, M Margaret Knudson, Thomas Scalea, Todd W Costantini, Lisa Marie Knowlton, David Spain, Ernest E Moore, Michelle K McNutt, Matthew J Martin, Andrew J Kerwin, George C Velmahos, Bruce Crookes, Marta McCrum, Lucy Kornblith, Mark D Cipolle, Laszlo N Kiraly, David J Milia, Alicia Mohr, Frederick Rogers, Sherry Sixta, Jade Nunez
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 9, Iss 1 (2024)
Introduction Optimal venous thromboembolism (VTE) enoxaparin prophylaxis dosing remains elusive. Weight-based (WB) dosing safely increases anti-factor Xa levels without the need for routine monitoring but it is unclear if it leads to lower VTE risk.
Externí odkaz:
https://doaj.org/article/443dc6eb294f4502a537ecd6ceae66dd
Autor:
Krislynn M Mueck, Charles E Wade, Bryan A Cotton, Gabrielle E Hatton, Mariela Sandoval, David T Lubkin, Jason B Brill, Jessica C Cardenas
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 9, Iss 1 (2024)
Objectives Some centers have recommended including concentrated fibrinogen replacement in massive transfusion protocols (MTPs). Given our center’s policy of aggressive early balanced resuscitation (1:1:1), beginning prehospital, we hypothesized tha
Externí odkaz:
https://doaj.org/article/1ac631a409354835b4d62764da172a06
Autor:
Joseph D. Krocker, Madeline E. Cotton, Jacob B. Schriner, Baron K. Osborn, Michael M. Talanker, Yao-Wei W. Wang, Charles S. Cox, Charles E. Wade
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The TRPM4 gene codes for a membrane ion channel subunit related to inflammation in the central nervous system. Recent investigation has identified an association between TRPM4 single nucleotide polymorphisms (SNPs) rs8104571 and rs150391806
Externí odkaz:
https://doaj.org/article/d350293ca1d4451a890a0d90031f6b45
Autor:
Andrew J. Benjamin, MD, Andrew J. Young, MD, John B. Holcomb, MD, Erin E. Fox, PhD, Charles E. Wade, PhD, Chris Meador, MBA, Jeremy W. Cannon, MD, SM
Publikováno v:
Annals of Surgery Open, Vol 4, Iss 3, p e314 (2023)
Objective:. Develop a novel machine learning (ML) model to rapidly identify trauma patients with severe hemorrhage at risk of early mortality. Background:. The critical administration threshold (CAT, 3 or more units of red blood cells in a 60-minute
Externí odkaz:
https://doaj.org/article/f0c2ff8f1f1143508eca454cf911e23d
Autor:
John B Holcomb, Charles C Miller, Charles E Wade, Jan Jansen, Jessica Cardenas, Daniel Lammers, Michelle Scerbo, Annamaria Davidson, Matthew Pommerening, Jeffrey Tomasek
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 8, Iss 1 (2023)
Background Trauma patients exhibit a multifactorial hypercoagulable state and have increased risk of venous thromboembolism (VTE). Despite early and aggressive chemoprophylaxis (CP) with various heparin compounds (“standard” CP; sCP), VTE rates r
Externí odkaz:
https://doaj.org/article/7bc96c48d9ba4efe80d4f13870b9ba47
Autor:
Charles E Wade, Bryan A Cotton, David E Meyer, Charles Cox, Jessica Cardenas, Jan-Michael Van Gent, Justin Gerard, Christian Gage
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 8, Iss 1 (2023)
Objectives Recent studies evaluating fibrinogen replacement in trauma, along with newly available fibrinogen-based products, has led to an increase in debate on where products such as cryoprecipitate belong in our resuscitation strategies. We set out
Externí odkaz:
https://doaj.org/article/c66c8b2fbf56499dbd07eae8948530f2
Autor:
Thaddeus J. Puzio, James Klugh, Michael W. Wandling, Charles Green, Julius Balogh, Samuel J. Prater, Christopher T. Stephens, Paulina B. Sergot, Charles E. Wade, Lillian S. Kao, John A. Harvin
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Evidence for effective pain management and opioid minimization of intravenous ketamine in elective surgery has been extrapolated to acutely injured patients, despite limited supporting evidence in this population. This trial seeks
Externí odkaz:
https://doaj.org/article/16d018459f65429cae9010c40dfde4a1
Autor:
Zhangsheng Yang, Tuan D. Le, Milomir O. Simovic, Bin Liu, Tamara L. Fraker, Tomas S. Cancio, Andrew P. Cap, Charles E. Wade, Jurandir J. DalleLucca, Yansong Li
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Complementopathy, endotheliopathy, and coagulopathy following a traumatic injury are key pathophysiological mechanisms potentially associated with multiple-organ failure (MOF) and mortality. However, the heterogeneity in the responses of complementop
Externí odkaz:
https://doaj.org/article/b6ce6c63274a47cb9a1f7940ee04ff76
Autor:
Hanne H. Henriksen, Igor Marín de Mas, Helena Herand, Joseph Krocker, Charles E. Wade, Pär I. Johansson
Publikováno v:
Matrix Biology Plus, Vol 15, Iss , Pp 100115- (2022)
Purpose: Endotheliopathy of trauma (EoT), as defined by circulating levels of syndecan-1 ≥ 40 ng/mL, has been reported to be associated with significantly increased transfusion requirements and a doubled 30-day mortality. Increased shedding of the
Externí odkaz:
https://doaj.org/article/bc9e607d6fdf4fef99148f2f6536f929
Autor:
Hanne H. Henriksen, Igor Marín de Mas, Lars K. Nielsen, Joseph Krocker, Jakob Stensballe, Sigurður T. Karvelsson, Niels H. Secher, Óttar Rolfsson, Charles E. Wade, Pär I. Johansson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2257 (2023)
In trauma patients, shock-induced endotheliopathy (SHINE) is associated with a poor prognosis. We have previously identified four metabolic phenotypes in a small cohort of trauma patients (N = 20) and displayed the intracellular metabolic profile of
Externí odkaz:
https://doaj.org/article/f54990fe50e240ebb44f0d7a0ed15e8c