Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Charles E, MacKay"'
Autor:
Sara Ranjbarvaziri, Aliya Zeng, Iris Wu, Amara Greer-Short, Farshad Farshidfar, Ana Budan, Emma Xu, Reva Shenwai, Matthew Kozubov, Cindy Li, Melissa Van Pell, Francis Grafton, Charles E MacKay, Xiaomei Song, James R Priest, Gretchen Argast, Mohammad A. Mandegar, Timothy Hoey, Jin Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Heart failure with preserved ejection fraction (HFpEF) poses therapeutic challenges due to the limited treatment options. Building upon our previous research that demonstrates the efficacy of histone deacetylase 6 (HDAC6) inhibition in a gen
Externí odkaz:
https://doaj.org/article/9658610d4ff04dbaabe514860e2f248f
Autor:
Sara Ranjbarvaziri, Aliya Zeng, Iris Wu, Amara Greer-Short, Farshad Farshidfar, Ana Budan, Emma Xu, Reva Shenwai, Matthew Kozubov, Cindy Li, Melissa Van Pell, Francis Grafton, Charles E MacKay, Xiaomei Song, James R Priest, Gretchen Argast, Mohammad A. Mandegar, Timothy Hoey, Jin Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/665b649400904d3780546ebb20c2a05d
Autor:
Charles E MacKay, Miranda Floen, M Dennis Leo, Raquibul Hasan, Tessa AC Garrud, Carlos Fernández-Peña, Purnima Singh, Kafait U Malik, Jonathan H Jaggar
Publikováno v:
eLife, Vol 11 (2022)
Polycystin-1 (PC-1, PKD1), a receptor-like protein expressed by the Pkd1 gene, is present in a wide variety of cell types, but its cellular location, signaling mechanisms, and physiological functions are poorly understood. Here, by studying tamoxifen
Externí odkaz:
https://doaj.org/article/cff651dd124f4c21a6809460ca82fa99
Autor:
Charles E MacKay, M Dennis Leo, Carlos Fernández-Peña, Raquibul Hasan, Wen Yin, Alejandro Mata-Daboin, Simon Bulley, Jesse Gammons, Salvatore Mancarella, Jonathan H Jaggar
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/3d59a7289b5448febd2cc8b73ecdb135
Autor:
Simon Bulley, Carlos Fernández-Peña, Raquibul Hasan, M Dennis Leo, Padmapriya Muralidharan, Charles E MacKay, Kirk W Evanson, Luiz Moreira-Junior, Alejandro Mata-Daboin, Sarah K Burris, Qian Wang, Korah P Kuruvilla, Jonathan H Jaggar
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/57ca6c039c234b1b9dfa699482d3dd89
Autor:
Charles E MacKay, M Dennis Leo, Carlos Fernández-Peña, Raquibul Hasan, Wen Yin, Alejandro Mata-Daboin, Simon Bulley, Jesse Gammons, Salvatore Mancarella, Jonathan H Jaggar
Publikováno v:
eLife, Vol 9 (2020)
PKD2 (polycystin-2, TRPP1), a TRP polycystin channel, is expressed in endothelial cells (ECs), but its physiological functions in this cell type are unclear. Here, we generated inducible, EC-specific Pkd2 knockout mice to examine vascular functions o
Externí odkaz:
https://doaj.org/article/0edd17b22fee4bf78730970a19190368
Autor:
Simon Bulley, Carlos Fernández-Peña, Raquibul Hasan, M Dennis Leo, Padmapriya Muralidharan, Charles E Mackay, Kirk W Evanson, Luiz Moreira-Junior, Alejandro Mata-Daboin, Sarah K Burris, Qian Wang, Korah P Kuruvilla, Jonathan H Jaggar
Publikováno v:
eLife, Vol 7 (2018)
Systemic blood pressure is determined, in part, by arterial smooth muscle cells (myocytes). Several Transient Receptor Potential (TRP) channels are proposed to be expressed in arterial myocytes, but it is unclear if these proteins control physiologic
Externí odkaz:
https://doaj.org/article/f772016efeb540b59ee6ece9140d0565
Autor:
Charles E MacKay, Miranda Floen, M Dennis Leo, Raquibul Hasan, Tessa AC Garrud, Carlos Fernández-Peña, Purnima Singh, Kafait U Malik, Jonathan H Jaggar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b4c24702875f03e42a7447db771eea5
https://doi.org/10.7554/elife.74765.sa2
https://doi.org/10.7554/elife.74765.sa2
Autor:
M. Dennis Leo, Simon Bulley, Wen Yin, Carlos Fernández-Peña, Padmapriya Muralidharan, Alejandro Mata-Daboin, Jonathan H. Jaggar, Raquibul Hasan, Charles E. Mackay
Publikováno v:
Proc Natl Acad Sci U S A
PKD2 (polycystin-2, TRPP1) channels are expressed in a wide variety of cell types and can regulate functions, including cell division and contraction. Whether posttranslational modification of PKD2 modifies channel properties is unclear. Similarly un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440653cfa11c11d45b723d2441d14dbe
https://doi.org/10.1073/pnas.1917264116
https://doi.org/10.1073/pnas.1917264116
Autor:
Luiz Moreira-Junior, Simon Bulley, Carlos Fernández-Peña, Sarah K. Burris, Korah P. Kuruvilla, Alejandro Mata-Daboin, M. Dennis Leo, Jonathan H. Jaggar, Kirk W. Evanson, Qian Wang, Padmapriya Muralidharan, Raquibul Hasan, Charles E. Mackay
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Systemic blood pressure is determined, in part, by arterial smooth muscle cells (myocytes). Several Transient Receptor Potential (TRP) channels are proposed to be expressed in arterial myocytes, but it is unclear if these proteins control physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccb995120fbf141591398095cdade20
https://elifesciences.org/articles/60403
https://elifesciences.org/articles/60403