Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Charles Decraene"'
Autor:
Isabel Paiva, Jonathan Seguin, Iris Grgurina, Akash Kumar Singh, Brigitte Cosquer, Damien Plassard, Laura Tzeplaeff, Stephanie Le Gras, Ludovica Cotellessa, Charles Decraene, Johanne Gambi, Rafael Alcala-Vida, Muthusamy Eswaramoorthy, Luc Buée, Jean-Christophe Cassel, Paolo Giacobini, David Blum, Karine Merienne, Tapas K. Kundu, Anne-Laurence Boutillier
Publikováno v:
Neurobiology of Disease, Vol 198, Iss , Pp 106538- (2024)
Aging is the main risk factor of cognitive neurodegenerative diseases such as Alzheimer's disease, with epigenome alterations as a contributing factor. Here, we compared transcriptomic/epigenomic changes in the hippocampus, modified by aging and by t
Externí odkaz:
https://doaj.org/article/f5714d9bc754442fab0e4c7aa97ead64
Autor:
Leonie Zeune, Guus van Dalum, Charles Decraene, Charlotte Proudhon, Tanja Fehm, Hans Neubauer, Brigitte Rack, Marianna Alunni-Fabbroni, Leon W M M Terstappen, Stephan A van Gils, Christoph Brune
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186562 (2017)
Circulating tumor cells (CTCs) isolated from blood can be probed for the expression of treatment targets. Immunofluorescence is often used for both the enumeration of CTC and the determination of protein expression levels related to treatment targets
Externí odkaz:
https://doaj.org/article/5b189963536340f4ae65c16c0f2d8299
Autor:
François-Clément Bidard, Nicolas Kiavue, Marc Ychou, Luc Cabel, Marc-Henri Stern, Jordan Madic, Adrien Saliou, Aurore Rampanou, Charles Decraene, Olivier Bouché, Michel Rivoire, François Ghiringhelli, Eric Francois, Rosine Guimbaud, Laurent Mineur, Faiza Khemissa-Akouz, Thibault Mazard, Driffa Moussata, Charlotte Proudhon, Jean-Yves Pierga, Trevor Stanbury, Simon Thézenas, Pascale Mariani
Publikováno v:
Cells, Vol 8, Iss 6, p 516 (2019)
The management of patients with colorectal cancer (CRC) and potentially resectable liver metastases (LM) requires quick assessment of mutational status and of response to pre-operative systemic therapy. In a prospective phase II trial (NCT01442935),
Externí odkaz:
https://doaj.org/article/47114e9137bc4e8588861221bc11490c
Autor:
Luc Cabel, Charles Decraene, Ivan Bieche, Jean-Yves Pierga, Mostefa Bennamoun, David Fuks, Jean-Marc Ferraz, Marine Lefevre, Sylvain Baulande, Virginie Bernard, Sophie Vacher, Pascale Mariani, Charlotte Proudhon, Francois-Clement Bidard, Christophe Louvet
Publikováno v:
Cancers, Vol 11, Iss 3, p 396 (2019)
This study was designed to monitor circulating tumor DNA (ctDNA) levels during perioperative chemotherapy in patients with non-metastatic gastric adenocarcinoma. Plasma samples were prospectively collected in patients undergoing perioperative chemoth
Externí odkaz:
https://doaj.org/article/f5945aeb60674570b21c45e0d839811f
Publikováno v:
BioTechniques, Vol 27, Iss 5, Pp 962-966 (1999)
Complex cDNA targets conforming to the nomenclature proposed by Duggan et al. (Nat. Genet. 21 [1 Suppl.]:10–14) (where the immobilized nucleic acid is called “probe” and free nucleic acid is called “target”) were prepared by priming reverse
Externí odkaz:
https://doaj.org/article/df011e81c6e74c2d94f4927d338ed896
Autor:
Yaser Atlasi, Rubina Noori, Claudia Gaspar, Patrick Franken, Andrea Sacchetti, Haleh Rafati, Tokameh Mahmoudi, Charles Decraene, George A Calin, Bradley J Merrill, Riccardo Fodde
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003424 (2013)
Canonical Wnt signaling plays a rate-limiting role in regulating self-renewal and differentiation in mouse embryonic stem cells (ESCs). We have previously shown that mutation in the Apc (adenomatous polyposis coli) tumor suppressor gene constitutivel
Externí odkaz:
https://doaj.org/article/80d2f51250424bcabe8ff7e8779eac5e
Autor:
Pierre Mordant, Yohann Loriot, Benoit Lahon, Yves Castier, Guy Lesèche, Jean-Charles Soria, Marie-Catherine Vozenin, Charles Decraene, Eric Deutsch
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26073 (2011)
BACKGROUND: Preclinical models of non-small cell lung cancer (NSCLC) require better clinical relevance to study disease mechanisms and innovative therapeutics. We sought to compare and refine bioluminescent orthotopic mouse models of human localized
Externí odkaz:
https://doaj.org/article/7c25d3b9719c4ef385b75deaa1b2f921
Autor:
Laurent Schibler, Linda Gibbs, Catherine Benoist-Lasselin, Charles Decraene, Jelena Martinovic, Philippe Loget, Anne-Lise Delezoide, Marie Gonzales, Arnold Munnich, Jean-Philippe Jais, Laurence Legeai-Mallet
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7633 (2009)
Endochondral ossification is the process by which the appendicular skeleton, facial bones, vertebrae and medial clavicles are formed and relies on the tight control of chondrocyte maturation. Fibroblast growth factor receptor (FGFR)3 plays a role in
Externí odkaz:
https://doaj.org/article/1d1cda7be60b46d78100f93aa72bb02c
In the past two decades, over-prescription of opioids for pain management has driven a steep increase in opioid use disorder (OUD) and death by overdose, exerting a dramatic toll on western countries. OUD is a chronic relapsing disease associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d2fca7123032bd9872232d066d94238
https://doi.org/10.1101/2022.12.22.521548
https://doi.org/10.1101/2022.12.22.521548
Autor:
Rafael Alcalá-Vida, Caroline Lotz, Baptiste Brulé, Jonathan Seguin, Charles Decraene, Ali Awada, Aurélie Bombardier, Brigitte Cosquer, Anne Pereira de Vasconcelos, Emmanuel Brouillet, Jean-Christophe Cassel, Anne-Laurence Boutillier, Karine Merienne
Publikováno v:
Progress in neurobiology. 219
Molecular mechanisms underlying cognitive deficits in Huntington's disease (HD), a striatal neurodegenerative disorder, are unknown. Here, we generated ChIPseq, 4Cseq and RNAseq data on striatal tissue of HD and control mice during striatum-dependent