Zobrazeno 1 - 10
of 840
pro vyhledávání: '"Charles DeCArli"'
Autor:
Rebeca Scalco, Luca C. Oliveira, Zhengfeng Lai, Danielle J. Harvey, Lana Abujamil, Charles DeCarli, Lee-Way Jin, Chen-Nee Chuah, Brittany N. Dugger
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Accurate and scalable quantification of amyloid-β (Aβ) pathology is crucial for deeper disease phenotyping and furthering research in Alzheimer Disease (AD). This multidisciplinary study addresses the current limitations on neuropathology
Externí odkaz:
https://doaj.org/article/db05312ca87d4aeab039bcdcaa3089b8
Autor:
Hsin-Pei Wang, Rebeca Scalco, Naomi Saito, Laurel Beckett, My-Le Nguyen, Emily Z. Huie, Lawrence S. Honig, Charles DeCarli, Robert A. Rissman, Andrew F. Teich, Dan M. Mungas, Lee-Way Jin, Brittany N. Dugger
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Cerebrovascular and α-synuclein pathologies are frequently observed alongside Alzheimer disease (AD). The heterogeneity of AD necessitates comprehensive approaches to postmortem studies, including the representation of historically underrep
Externí odkaz:
https://doaj.org/article/2ccca9693bd8481a91ee168a49211a38
Autor:
Shraddha Sapkota, Pauline Maillard, Ariana M. Stickel, Wassim Tarraf, Kevin A. Gonzalez, Vladimir Ivanovic, Alejandra Morlett‐Paredes, Jianwen Cai, Carmen R. Isasi, Richard B. Lipton, Martha Daviglus, Fernando Daniel Testai, Melissa Lamar, Linda C. Gallo, Gregory A. Talavera, Christian Agudelo, Alberto R. Ramos, Hector M. González, Charles DeCarli
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract The Hispanic/Latino population is one of the largest and most diverse ethnoracial groups in the United States at high risk for dementia. We examined cognitive constructs and associations with subsequent hippocampal volume (HV) and white matt
Externí odkaz:
https://doaj.org/article/cd13a84f97854114bb5e5ed21dafcf73
Autor:
Ariana M. Stickel, Wassim Tarraf, Kevin A. Gonzalez, Alejandra Morlett Paredes, Donglin Zeng, Jianwen Cai, Carmen R. Isasi, Robert Kaplan, Richard B. Lipton, Martha L. Daviglus, Fernando D. Testai, Melissa Lamar, Linda C. Gallo, Gregory A. Talavera, Marc D. Gellman, Alberto R. Ramos, Vladimir Ivanovic, Stephan Seiler, Hector M. González, Charles DeCarli
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundCardiovascular disease (CVD) risk factors are highly prevalent among Hispanic/Latino adults, while the prevalence of MRI infarcts is not well-documented. We, therefore, sought to examine the relationships between CVD risk factors and infarc
Externí odkaz:
https://doaj.org/article/a7449ad033f54a1abf335dc1939002ad
Autor:
Shiraz Vered, Alexa S. Beiser, Liron Sulimani, Sharon Sznitman, Mitzi M. Gonzales, Hugo J. Aparicio, Charles DeCarli, Matthew R. Scott, Saptaparni Ghosh, Gil M. Lewitus, David Meiri, Sudha Seshadri, Galit Weinstein
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Preclinical studies highlight the importance of endogenous cannabinoids (endocannabinoids; eCBs) in neurodegeneration. Yet, prior observational studies focused on limited outcome measures and assessed only few eCB compounds while
Externí odkaz:
https://doaj.org/article/093f68cbea874b4aa79ffe745a7b724d
Autor:
Bernard Fongang, Claudia Satizabal, Tiffany F. Kautz, Yannick N. Wadop, Jazmyn A. S. Muhammad, Erin Vasquez, Julia Mathews, Monica Gireud-Goss, Amy R. Saklad, Jayandra Himali, Alexa Beiser, Jose E. Cavazos, Michael C. Mahaney, Gladys Maestre, Charles DeCarli, Eric L. Shipp, Ramachandran S. Vasan, Sudha Seshadri
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract A bidirectional communication exists between the brain and the gut, in which the gut microbiota influences cognitive function and vice-versa. Gut dysbiosis has been linked to several diseases, including Alzheimer's disease and related dement
Externí odkaz:
https://doaj.org/article/6cd56d8bd3934f04aeef2cc00faa8818
Autor:
Daniel R. Wong, Shino D. Magaki, Harry V. Vinters, William H. Yong, Edwin S. Monuki, Christopher K. Williams, Alessandra C. Martini, Charles DeCarli, Chris Khacherian, John P. Graff, Brittany N. Dugger, Michael J. Keiser
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Precise, scalable, and quantitative evaluation of whole slide images is crucial in neuropathology. We release a deep learning model for rapid object detection and precise information on the identification, locality, and counts of cored plaqu
Externí odkaz:
https://doaj.org/article/c3d3f3daf1b44aed967015946cc7eb2d
Autor:
Rebeca Scalco, Naomi Saito, Laurel Beckett, My-Le Nguyen, Emily Huie, Hsin-Pei Wang, Delaney A. Flaherty, Lawrence S. Honig, Charles DeCarli, Robert A. Rissman, Andrew F. Teich, Lee-Way Jin, Brittany N. Dugger
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Despite the increasing demographic diversity of the United States’ aging population, there remain significant gaps in post-mortem research investigating the ethnoracial heterogeneity in the neuropathological landscape of Alzheimer Disease
Externí odkaz:
https://doaj.org/article/c400d7d0dfbe4c4d88b0540088c7067d
Autor:
Charles DeCarli, Pauline Maillard, Ariana Stickel, Wassim Tarraf, Kevin Gonzalez, Alejandra Morlett-Paredes, Donglin Zeng, Jianwen Cai, Carmen Isasi, Robert Kaplan, Richard Lipton, Martha Daviglus, Fernando Testai, Melissa Lamar, Linda Gallo, Gregory Talavera, Alberto Ramos, Vladimir Ivanovic, Stephan Seiler, Hector Gonzalez
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100287- (2024)
Introduction: HCHS/SOL is a representative study of Hispanic/Latinos living in the US. SOL-INCA examines cognition amongst those of HCHS/SOL over age 50 and SOL-INCA-MRI obtains quantitative MRI measures on a subgroup of these individuals. Prior rese
Externí odkaz:
https://doaj.org/article/439d2ed5b6444d64b614d54c3c071da6
Autor:
Vincent Chen, Ariana Stickel, Wassim Tarraf, Kevin Gonzalez, Donglin Zeng, Jianwen Cai, Carmen Isasi, Robert Kaplan, Richard Lipton, Martha Daviglus, Fernando Testai, Melissa Lamar, Linda Gallo, Gregory Talavera, Vladimir Ivanovic, Stephan Seiler, Hector Gonzalez, Charles DeCarli
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100289- (2024)
Introduction: HCHS/SOL is a representative study of Hispanic/Latinos living in the US. HCHS/SOL participants have a high prevalence of diabetes (1) and diabetic associated cognitive decline (2). Previous studies of predominantly non-Hispanic White po
Externí odkaz:
https://doaj.org/article/1279491c63cd4d70ba7e5fa6c46d8206