Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Charles Danzin"'
Autor:
Mirlyse Siat, Pierre S. Mamont, Charles Danzin, Nicole Claverie, Joseph Wagner, Anne-Marie Joder-Ohlenbusch
Publikováno v:
European Journal of Biochemistry. 123:499-504
Biological transmethylation reactions and polyamine biosynthesis share the substrate S-adenosyl-L-methionine. Under normal conditions, decarboxylated S-adenosyl-L-methionine, the aminopropyl donor for polyamine biosynthesis, does not accumulate becau
Autor:
Claire Cudrey, Carole Bloës, Catherine Gueguen, Robert Verger, Dolores Ludevid, Claude Benicourt, Thierry Arnaud, Séverine Jacquet, Veronique Gruber, Nathalie Zorn, Dominique Mison, Bertrand Merot, Béatrice Olagnier, Christèle Clément, Sylvie Baudino, Manfred Theisen, Patrick P. Berna, Sylvie Dufour, Alain Van Dorsselaer, Christine Poncetta, Philippe Bournat, Charles Danzin, Catherine Ollivo, Nathalie Duchateau, Annette Marian Doherty, Laurence Philippe
Publikováno v:
Molecular Breeding. 7:329-340
A recombinant dog gastric lipase with therapeutic potential for the treatment of exocrine pancreatic insufficiency was expressed in transgenic tobacco plants. We targeted the protein using two different signal sequences for either vacuolar retention
Publikováno v:
Bioorganic Chemistry. 24:178-193
The design, synthesis, and biologic evaluation of potential silicon-containing inhibitors of diamine oxidases (siladiaminopropane 1 , silaputrescine 2 , and sila analogs of cadaverine 3, 4, and 5 ) are described. All compounds have been prepared inde
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:393-396
Several unsaturated thioacetic acids were synthesized as potential mechanism-based inhibitors of peptidyglycine α-hydroxylating monooxygenase (PHM) prepared from horse serum. Trans-styrylthioacetic acid produced potent time-dependent inhibition of P
Publikováno v:
Tetrahedron. 52:177-184
The phosphonate derivatives of N9-benzylguanine (4a–4h) have been prepared as purine nucleoside phophorylase inhibitors. Enzyme inhibition studies with PNP from calf spleen or human erythrocyte show that compounds 4b and 4c are among the best PNP i
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2363-2366
Several organosilicon amines were synthesized as potential mechanism-based inhibitors of semicarbazide-sensitive amine oxidase (SSAO) prepared from rat aorta. 2-[Dimethyl(2-phenylethyl)silyl]-methanamine, hydrochloride produced potent time-dependent
Autor:
Daniel Schirlin, Pierrette Marchal, Charles Danzin, Monique Zreika, Petty Margaret A, Jean-Noel Collard
Publikováno v:
Biochemical Society Transactions. 22:768-773
Publikováno v:
ChemInform. 22
Autor:
Jean-Bernard Ducep, Joseph Wagner, Daniel Schirlin, J. Fischer, J. M. Hornsperger, A. Mitschler, Raymond Weiss, Jean-Georges Heydt, Philippe Bey, Michel Jung, S. Baltzer, Charles Danzin, A. De Cian, F. Piriou
Publikováno v:
ChemInform. 23
The synthesis of α-(chlorofluoromethyl)-ornithine 7, -metatyrosine 8 and -glutamic acid 14 is described. Separation of diastereoisomers and relative configuration assignment by X-ray analysis are reported. Assignment of absolute configuration of the
Publikováno v:
ChemInform. 24
A series of 6-deoxy-6-fluorinated glucosides have been synthesized and evaluated as inhibitors of yeast α-glucosidase. These compounds have a 7- to 25-fold higher affinity than the corresponding 6-hydroxy derivatives. The most potent inhibitor in th