Výsledky vyhledávání - "Charles D. Boyd"

Persistent Inflammatory Pathways Associated with Early Onset Myocardial Infarction in a Medicated Multiethnic Hawaiian Cohort

Autor: Matthew B. Heller, Kornelia M. Szauter, Matthias K. Jansen, Michael Loomis, Katalin Csiszar, James H. Kimura, Tercia Ku, Richard A. Girton, Charles D. Boyd, Gordon Okimoto, Maarit Tiirikainen

Publikováno v: Biochemistry Insights, Vol 2011, Iss 4, Pp 13-27 (2011)
Biochemistry Insights, Vol 4 (2011)

In spite of current standard therapies to target the major pathomechanisms in myocardial infarction (MI), inflammatory gene expression patterns have been consistently revealed in MI patients. In a multiethnic cohort, we aimed to identify MI-associate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28263206d1a806f2482054d75de48131
http://www.la-press.com/persistent-inflammatory-pathways-associated-with-early-onset-myocardia-a2640

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A novel fibrotic disorder associated with increased dermal fibroblast proliferation and downregulation of genes of the microfibrillar network

Autor: R. M. Laxer, A. Hinek, Kornelia M. Szauter, Elena Pope, Katalin Csiszar, Anita Ordas, Charles D. Boyd, D. Wherrett, Mátyás Mink, Benjamin A. Alman

Publikováno v: British Journal of Dermatology. 163:1102-1115

Clinical evaluation of a young woman with subcutaneous fibrotic nodules, progressive distal joint contractures and marfanoid stature revealed a previously unrecognized fibrotic disorder characterized by several unique phenotypic features and some fea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0d2182d3fd88935723fc73908ed9c92
https://doi.org/10.1111/j.1365-2133.2010.09911.x

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Analysis of ABCC6 (MRP6) in normal human tissues

Autor: Kimiko Hayashi, Charles D. Boyd, Konstanze Beck, Masando Hayashi, Ka’ohimanu Dang

Publikováno v: Histochemistry and Cell Biology. 123:517-528

To determine the tissue distribution of the ABC transporter ABCC6 in normal human tissues, we analyzed tissue arrays for the presence of ABCC6 mRNA by in situ hybridization and ABCC6 protein by immunohistochemistry using the polyclonal antibody HB-6.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0057867f6c1b8806fe5f9ccc3f5acfe3
https://doi.org/10.1007/s00418-004-0744-3

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Comparative immunocytochemical localization of lysyl oxidase (LOX) and the lysyl oxidase-like (LOXL) proteins: changes in the expression of LOXL during development and growth of mouse tissues

Autor: Katalin Csiszar, Masando Hayashi, Charles D. Boyd, Keith S. K. Fong, Frederic Mercier, Kimiko Hayashi

Publikováno v: Journal of Molecular Histology. 35:845-855

Lysyl oxidase (LOX) and lysyl oxidase-like (LOXL) are extracellular enzymes that deaminate peptidyl lysyl residues involved in the cross-linking of fibrillar collagens and elastin. While LOX is required for the survival of newborn mice, the role of L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34145a454ff5ae11c2dd05596cc1e232
https://doi.org/10.1007/s10735-004-2340-1

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The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family

Autor: C. Sung, Steven Robinow, Charles D. Boyd, András Váradi, J. N. Tarnay, Attila Iliás, Flóra Szeri, Tarmo Annilo, Michael Dean, O. Le Saux

Publikováno v: Insect Molecular Biology. 13:539-548

ATP-binding cassette (ABC) transporters are involved in the transport of substrates across biological membranes and are essential for many cellular processes. Of the fifty-six Drosophila ABC transporter genes only white, brown, scarlet, E23 and Atet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec3291b1b104e0f678cc16803968155
https://doi.org/10.1111/j.0962-1075.2004.00512.x

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The Distribution of Abcc6 in Normal Mouse Tissues Suggests Multiple Functions for this ABC Transporter

Autor: Olivier Le Saux, Konstanze Beck, Brian Nishiguchi, Charles D. Boyd, Masando Hayashi, Kimiko Hayashi

Publikováno v: Journal of Histochemistry & Cytochemistry. 51:887-902

We have studied the tissue distribution of Abcc6, a member of the ABC transmembrane transporter subfamily C, in normal C57BL/6 mice. RNase protection assays revealed that although almost all tissues studied contained detectable levels of the mRNA enc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f79c0ed3eb3515b5252ab9813f31022
https://doi.org/10.1177/002215540305100704

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Evidence for a founder effect for pseudoxanthoma elasticum in the Afrikaner population of South Africa

Autor: Christine Sachsinger, Anna Susan Marais, Eric W. Johnson, Lionel Bercovitch, Sharon F. Terry, Carina Treiber, Harald H H Göring, Konstanze Beck, Charles D. Boyd, Katie Curry, Denis Viljoen, Olivier Le Saux

Publikováno v: Human Genetics. 111:331-338

Pseudoxanthoma elasticum (PXE) is a heritable elastic tissue disorder recently shown to be attributable to mutations in the ABCC6 ( MRP6) gene. Whereas PXE has been identified in all ethnic groups studied to date, the prevalence of this disease in va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909475c3d62009d09b95652c40a4223e
https://doi.org/10.1007/s00439-002-0808-1

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A Serial Analysis of Gene Expression in Sun-Damaged Human Skin

Autor: Katalin Csiszar, Chia Granda, Zsolt Urban, Johann Urschitz, Susanne Teklits Iobst, Claudia Lupp, Charles D. Boyd, Kathleen A Souza, Kurt Matthew Schilling, Ian Richard Scott

Publikováno v: Journal of Investigative Dermatology. 119:3-13

To study the phenotypic changes in human skin associated with repeated sun exposure at the transcription level, we have undertaken a comparative serial analysis of gene expression of sun-damaged preauricular skin and sun-protected postauricular skin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1530e96bd535f21633957c8b6065e15b
https://doi.org/10.1046/j.1523-1747.2002.01829.x

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Loss of ATP-dependent Transport Activity in Pseudoxanthoma Elasticum-associated Mutants of Human ABCC6 (MRP6)

Autor: Olivier Le Saux, Thomas L. Seidl, Zsolt Urban, Balázs Sarkadi, András Váradi, Attila Iliás, Emese Sinkó, Charles D. Boyd

Publikováno v: Journal of Biological Chemistry. 277:16860-16867

Mutations in the ABCC6 (MRP6) gene cause pseudoxanthoma elasticum (PXE), a rare heritable disorder resulting in the calcification of elastic fibers. In the present study a cDNA encoding a full-length normal variant of ABCC6 was amplified from a human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592470774f525b468136c37f89341034
https://doi.org/10.1074/jbc.m110918200

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Supravalvular aortic stenosis: genetic and molecular dissection of a complex mutation in the elastin gene

Autor: Margaret R. Wallace, Gregg K. Maeda, Zsolt Urban, Elaine C. Davis, Heather J. Stalker, Jun Zhang, Charles D. Boyd, Anil Kumar, John W. Belmont

Publikováno v: Human Genetics. 109:512-520

We have identified two elastin gene (ELN) mutations located in cis in two related families with supravalvular aortic stenosis (SVAS). These mutations included an in-frame duplication in exon 18 (1034-1057dup) and a single base substitution in exon 26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da8dc2f9ce1c582b165b6f388fd9fa5
https://doi.org/10.1007/s00439-001-0608-z

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