Výsledky vyhledávání - "Charles D James"

Akademický článek

Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas

Autor: Rebecca Lewis, Yuping D Li, Lindsey Hoffman, Rintaro Hashizume, Gordan Gravohac, Gavin Rice, Nitin R Wadhwani, Chunfa Jie, Tatiana Pundy, Barbara Mania-Farnell, Chandra S Mayanil, Marcelo B Soares, Ting Lei, Charles D James, Nicolas K Foreman, Tadanori Tomita, Guifa Xi

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 6, Pp 505-515 (2019)

BACKGROUND: Ependymomas (EPNs) are the third most common brain tumor in children. These tumors are resistant to available chemotherapeutic treatments, therefore new effective targeted therapeutics must be identified. Increasing evidence shows epigene

Externí odkaz: https://doaj.org/article/6863059839ef4cb38ffe94340dddc14d

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Supplementary Tables from Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival

Autor: Derek A. Wainwright, Roger Stupp, Craig Horbinski, Charles D. James, Francis J. Giles, Jeffrey A. Sosman, David C. Binder, Priscilla K. Brastianos, Balázs Győrffy, Galina Gritsina, Matthew Genet, Meijing Wu, Kristen L. Lauing, Erik Ladomersky, Lijie Zhai

Description of Supplementary Tables 1-5 that support the expression and clinical relevance of IDO1 in grades II and III glioma, as well as GBM.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2332c3e7bebf670aea764df91787fc24
https://doi.org/10.1158/1078-0432.22469210.v1

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Supplementary Materials and Methods from Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival

Description of Materials and Methods used to generate the novel IDO1-overexpressing U87 cell line, Western blotting, RT-PCR, cancer genome atlas analysis, as well as high performance liquid chromatography.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0519b7327be62db20559b6b56c112e0f
https://doi.org/10.1158/1078-0432.22469213

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Supplementary Figures from Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival

Description of Supplementary Figures 1-9 that support the expression and clinical relevance of IDO1 in human GBM.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e865efa6e1324fa537eb8f53dc7a4e
https://doi.org/10.1158/1078-0432.22469216

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Abstract LB335: Establishment of the effective dose of the STAT3 inhibitor WP1066 used in combination with STING activation for reprograming the preclinical glioma microenvironment

Autor: Hinda Najem, Shashwat Tripathi, Moloud Sooreshjani, Lisa Hurley, Corey Dussold, Victor Arrieta, Martina Ott, Jun Wei, Michael Curran, Anantha Marisetty, Waldemar Priebe, Leondias C. Platanias, Maciej S. Lesniak, Charles D. James, Craig Horbinski, David M. Ashley, Amy B. Heimberger

Publikováno v: Cancer Research. 83:LB335-LB335

Purpose: Trials of immunotherapy in diffuse glioma patients have been mostly unsuccessful. We therefore sought to determine the combined effects of the signal transducer and activator of transcription 3 (STAT3) inhibitor WP1066 and the STING agonist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14af4b623d1959fbafbd579aa815acdc
https://doi.org/10.1158/1538-7445.am2023-lb335

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Abstract 3281: DNMT targeting enhances vulnerability of glioblastoma cells to MNK inhibition

Autor: Candice Mazewski, Frank Eckerdt, Aneta Baran, Mariafausta Fischietti, Purav P. Vagadia, Ricardo E. Perez, Charles D. James, Gary E. Schiltz, Leonidas C. Platanias

Publikováno v: Cancer Research. 82:3281-3281

Many factors complicate therapeutic strategies for glioblastoma (GBM), including the existence of the blood brain barrier and a heterogenous population of difficult to treat glioma stem cells. Innovative strategies targeting novel pathways alone or i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0460b7f4e4d4bbdb9cda83afbc413c1
https://doi.org/10.1158/1538-7445.am2022-3281

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Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia

Autor: Neil E. Kay, Curtis A. Hanson, Cristine Allmer, Nancy D. Bone, Stephanie R. Brockman, Thomas E. Witzig, Renee C. Tschumper, Judith R. O'Fallon, Rajiv K. Pruthi, Charles D. James, Timothy G. Call, Gordon W. Dewald, Sarah F. Paternoster, Diane F. Jelinek

Publikováno v: British Journal of Haematology. 121:287-295

Fluorescence in situ hybridization (FISH) was used to detect 6q-, 11q-, +12, 13q-, 17p- and translocations involving 14q32 in interphase nuclei from blood and/or bone marrow from 113 patients with B-cell chronic lymphocytic leukaemia (B-CLL). A total

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::159bab7e747424091f3769195a633a0d
https://doi.org/10.1046/j.1365-2141.2003.04265.x

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High Performance Liquid Chromatographic Assay for Cisatracurium and Its Metabolites in Human Urine

Autor: Jane Croft Harrelson, B. J. Bryant, D. Ryan Cook, Charles D. James

Publikováno v: Journal of Liquid Chromatography & Related Technologies. 20:2041-2051

An HPLC assay for the analysis of cisatracurium and its metabolites, laudanosine and the cis-monoquaternary alcohol (MQA), in human urine was developed. The assay involved solid-phase extraction followed by HPLC analysis on a strong cation exchange c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9ccba7742d1a782a1891d2533cccbd0
https://doi.org/10.1080/10826079708005563

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Safety, pharmacokinetics and pharmacodynamics of remogliflozin etabonate, a novel SGLT2 inhibitor, and metformin when co-administered in subjects with type 2 diabetes mellitus

Autor: Charles D James, Robert L. Dobbins, Robin L. O'Connor-Semmes, Joseph W. Polli, Bryan Rafferty, Elizabeth K. Hussey, Anita Kapur, Wenli Tao

Publikováno v: BMC Pharmacology & Toxicology

Background The sodium-dependent glucose co-transporter-2 (SGLT2) is expressed in absorptive epithelia of the renal tubules. Remogliflozin etabonate (RE) is the prodrug of remogliflozin, the active entity that inhibits SGLT2. An inhibitor of this path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b676381e67d29d421bb8e9a6b5ed80
https://doi.org/10.1186/2050-6511-14-25

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Regarding 'Shifting Sands' (Fall 2010)

Autor: Charles D. James

Publikováno v: Issues in Science and Technology Librarianship.

A letter to the editor is presented in response to the article "Shifting Sands: Science Researchers on Google Scholar, Web of Science and PubMed With Implications for Library Collections Budgets," published in a previous issue of "Issues in Science a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51750d676bd63832ce5015a7e9336868
https://doi.org/10.29173/istl1505

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