Zobrazeno 1 - 10
of 679
pro vyhledávání: '"Charles D, Pusey"'
Autor:
Mark E. McClure, Seerapani Gopaluni, James Wason, Robert B. Henderson, Andre Van Maurik, Caroline C.O. Savage, Charles D. Pusey, Alan D. Salama, Paul A. Lyons, Jacinta Lee, Kim Mynard, David R. Jayne, Rachel B. Jones, on behalf the COMBIVAS investigators
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Sequential B cell-targeted immunotherapy with BAFF antagonism (belimumab) and B cell depletion (rituximab) may enhance B cell targeting in ANCA-associated vasculitis (AAV) through several mechanisms. Methods Study design: COMBIVAS
Externí odkaz:
https://doaj.org/article/de0d5603a4e24992b66dd2efe0d957ae
Autor:
Shenzhen Tempest-Roe, Maria Prendecki, Stephen P. McAdoo, Candice Clarke, Anisha Tanna, Tabitha Turner-Stokes, Esteban S. Masuda, Michelle Willicombe, H. Terence Cook, Candice Roufosse, David Taube, Charles D. Pusey, Frederick W. K. Tam
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Antibody mediated rejection is a major cause of renal allograft loss. Circulating preformed donor specific antibodies (DSA) can result as a consequence of blood transfusion, pregnancy or prior transplantation. Current treatment strategies ar
Externí odkaz:
https://doaj.org/article/657abd7f4c754b5aa4ed59b73337583f
Autor:
David Jayne, Michael Walsh, Peter A Merkel, Chen Au Peh, Wladimir Szpirt, Xavier Puéchal, Shouichi Fujimoto, Carmel Hawley, Nader Khalidi, Rachel Jones, Oliver Flossmann, Ron Wald, Louis Girard, Adeera Levin, Gina Gregorini, Lorraine Harper, William Clark, Christian Pagnoux, Ulrich Specks, Lucy Smyth, Toshiko Ito-Ihara, Janak de Zoysa, Biljana Brezina, Andrea Mazzetti, Carol A McAlear, Donna Reidlinger, Samir Mehta, Natalie Ives, Elizabeth A Brettell, Hugh Jarrett, Keith Wheatley, Elizabeth Broadhurst, Alina Casian, Charles D Pusey
Publikováno v:
Health Technology Assessment, Vol 26, Iss 38 (2022)
Background: Anti-neutrophil cytoplasm antibody-associated vasculitis is a multisystem, autoimmune disease that causes organ failure and death. Physical removal of pathogenic autoantibodies by plasma exchange is recommended for severe presentations, a
Externí odkaz:
https://doaj.org/article/d0a874aa7a77433586be6d35e45e9780
Autor:
Aikaterini Nikolopoulou, Isabel Huang-Doran, Stephen P. McAdoo, Megan E. Griffith, H. Terence Cook, Charles D. Pusey
Publikováno v:
Kidney International Reports, Vol 4, Iss 11, Pp 1577-1584 (2019)
Introduction: Membranous glomerulonephritis (MGN) is rarely associated with necrotizing and crescentic glomerulonephritis (NCGN). Methods: We report the clinical and pathologic findings in 15 patients with MGN and NCGN associated with anti-neutrophil
Externí odkaz:
https://doaj.org/article/de230865076a4f8ea45340f7efda6656
Autor:
Aikaterini Nikolopoulou, Marie Condon, Tabitha Turner-Stokes, H. Terence Cook, Neill Duncan, Jack W. Galliford, Jeremy B. Levy, Liz Lightstone, Charles D. Pusey, Candice Roufosse, Thomas D. Cairns, Megan E. Griffith
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Tacrolimus (TAC) is effective in treating membranous nephropathy (MN); however relapses are frequent after treatment cessation. We conducted a randomised controlled trial to examine whether the addition of mycophenolate mofetil (M
Externí odkaz:
https://doaj.org/article/b42aec24ca99469f9ae73d6fe370b462
Plasma exchange as an adjunctive therapy in anti-neutrophil cytoplasm antibody-associated vasculitis
Autor:
Kavita Gulati, Charles D Pusey
Publikováno v:
Expert Review of Clinical Immunology. 19:417-430
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::843e6dfcaf9e6082027ca741176a0f51
https://doi.org/10.1080/1744666x.2023.2184354
https://doi.org/10.1080/1744666x.2023.2184354
Autor:
Stephen P. McAdoo, Charles D. Pusey
Publikováno v:
Nephrology Self-Assessment Program. 21:364-382
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee3932df2d823c7772d9ff83d24e382
https://doi.org/10.1681/nsap.00122022
https://doi.org/10.1681/nsap.00122022
Autor:
Nicholas R. Medjeral-Thomas, Anne Troldborg, Nicholas Constantinou, Hannah J. Lomax-Browne, Annette G. Hansen, Michelle Willicombe, Charles D. Pusey, H. Terence Cook, Steffen Thiel, Matthew C. Pickering
Publikováno v:
Kidney International Reports, Vol 3, Iss 2, Pp 426-438 (2018)
IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment. Complement deposition through the alternative and lectin activation pathways is associated with renal
Externí odkaz:
https://doaj.org/article/343f738fd1b549c1931233d31f58310f
Autor:
Lauren Floyd, Sebastian Bate, Abdul Hadi Kafagi, Nina Brown, Jennifer Scott, Mukunthan Srikantharajah, Marek Myslivecek, Graeme Reid, Faten Aqeel, Doubravka Frausova, Marek Kollar, Phuong Le Kieu, Bilal Khurshid, Charles D. Pusey, Ajay Dhaygude, Vladimir Tesar, Stephen McAdoo, Mark A. Little, Duvuru Geetha, Silke R. Brix
Publikováno v:
Journal of the American Society of Nephrology. 34:505-514
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a891fc23cf7a1c876b1b672dd6c566ec
https://doi.org/10.1681/asn.2022050581
https://doi.org/10.1681/asn.2022050581
Autor:
Marie Pereira, Tai-Di Chen, Norzawani Buang, Antoni Olona, Jeong-Hun Ko, Maria Prendecki, Ana S.H. Costa, Efterpi Nikitopoulou, Laura Tronci, Charles D. Pusey, H. Terence Cook, Stephen P. McAdoo, Christian Frezza, Jacques Behmoaras
Publikováno v:
Cell Reports, Vol 28, Iss 2, Pp 498-511.e5 (2019)
Summary: Iron is an essential metal that fine-tunes the innate immune response by regulating macrophage function, but an integrative view of transcriptional and metabolic responses to iron perturbation in macrophages is lacking. Here, we induced acut
Externí odkaz:
https://doaj.org/article/52934f4eeed3453cb2969714de777c3f