Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Charles C. Y. Shih"'
Autor:
Laura C. Bott, J. Paul Taylor, Masahisa Katsuno, George G. Harmison, Nisha M. Badders, Elaine Bautista, Nico P. Dantuma, Charles C.-Y. Shih, Carlo Rinaldi, Ke-lian Chen, Kenneth H. Fischbeck, Gen Sobue
Publikováno v:
Human Molecular Genetics. 25:1979-1989
Spinal and bulbar muscular atrophy (SBMA, also known as Kennedy's disease) is one of nine neurodegenerative disorders that are caused by expansion of polyglutamine-encoding CAG repeats. Intracellular accumulation of abnormal proteins in these disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddbac9762d7a971a1d04738a2ae30a6
https://doi.org/10.1093/hmg/ddw073
https://doi.org/10.1093/hmg/ddw073
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:2527-2534
4-Ethoxycarbonylethyl curcumin (ECECur) ( 3 ) is a current drug candidate for the treatment of prostate cancer. Due to problems inherent in the tautomerism of ECECur, 4-fluoro-4-ethoxycarbonylethyl curcumin ( 4 ) and 4-ethoxycarbonylethylenyl curcumi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce43f2e79213bd3bbdeb47560af849e3
https://doi.org/10.1016/j.bmc.2005.11.034
https://doi.org/10.1016/j.bmc.2005.11.034
Publikováno v:
Journal of Agricultural and Food Chemistry. 53:1379-1386
In this study, a liquid chromatography (LC)/turbo ion spray (TIS)-mass spectrometry (MS) method was developed to examine the chromatography or "fingerprint profile" of seven Cimicifuga herbs and six Cimicifuga racemosa (black cohosh) commercial produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b9ae64ea0c8f56b72a68d5e0419e48
https://doi.org/10.1021/jf048300d
https://doi.org/10.1021/jf048300d
Autor:
Hironori Ohtsu, Tzuying Chiang, Zhiyan Xiao, Ching-Yuan Su, Eugene Chang, Kuo Hsiung Lee, Charles C. Y. Shih, Hideji Itokawa, Chawnshang Chang, Yi-Fen Lee, Shang Yi Chiu
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:5083-5090
Fifteen new diarylheptanoids were synthesized and evaluated for antagonistic activity against androgen receptor (AR)-mediated reporter gene transcription using DU145, PC-3, and LNCaP prostate cancer cell lines. Most compounds showed activity in a 5α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::696b353ec0c173150ca6d843fcd39711
https://doi.org/10.1016/j.bmc.2003.08.029
https://doi.org/10.1016/j.bmc.2003.08.029
Autor:
Chawnshang Chang, Eugene Chang, Charles C. Y. Shih, Yi-Fen Lee, Junko Ishida, Zhiyan Xiao, Hideji Itokawa, Masahiro Nagai, Hironori Ohtsu, Kuo Hsiung Lee, Ching-Yuan Su, Tzuying Chiang, Hui Kang Wang, Meng Yin Tsai
Publikováno v:
Journal of Medicinal Chemistry. 45:5037-5042
A number of curcumin analogues were prepared and evaluated as potential androgen receptor antagonists against two human prostate cancer cell lines, PC-3 and DU-145, in the presence of androgen receptor (AR) and androgen receptor coactivator, ARA70. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce1a970466034f2f6ef83ec1e814650
https://doi.org/10.1021/jm020200g
https://doi.org/10.1021/jm020200g
Autor:
Li-Ping Jin, Xiang-Dong Ji, Charles C. Y. Shih, Chihuei Wang, Min Wang, Qi Guan, Win-Jing Young, Chawnshang Chang
Publikováno v:
Molecular and Cellular Biochemistry. 201:131-140
Several monoclonal antibodies (mAbs) and novel mAb-based assays for the androgen receptors (AR) have been developed. Large amounts of the recombinant human AR protein produced by a baculovirus expression system were used as an antigen to produce mAbs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8ed88085d2952e4d0c7b86ab34bd932
https://doi.org/10.1023/a:1007054210133
https://doi.org/10.1023/a:1007054210133
Autor:
Kenneth S.S. Chang, Shwu-Fen Jiang, Kai-Ping N. Chow, Charles C. Y. Shih, Hong-Sheng Kong, Jin-Bau Fu
Publikováno v:
Journal of Biomedical Science. 5:332-342
The regulation of CD28/B7 is important in T-cell activation. It has been argued that its aberrant expression is involved in the radiosensitivity of B-cell-stimulated T-cell response. Here, this possibility is studied in the mixed lymphocyte reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88b4d96ac7489380be87edb2d17fe79
https://doi.org/10.1007/bf02253443
https://doi.org/10.1007/bf02253443
Autor:
Hsu-Mei Hsu, Li-Ching Hsu, Yu-Chung Chang, Jin-Bau Fu, Kenneth S.S. Chang, Mei-Shang Ho, Kai-Ping N. Chow, Carlos Alberto Mandarim-de-Lacerda, Hong Chen, Francisco Borrego, Kang-Mai Wu, Chih-Feng Lu, Siu-Wah Chung, Cheng-Po Hu, Charles C. Y. Shih, John E. Coligan, Shwu-Fen Jiang, Wan-Jr Syu, Peter M. C. Wong, Rene Daniel, Leila Maria Meirelles Pereira, Ching-Gong Lin, Sung-Liang Yu, Shiang-Fen Huang, Hong-Sheng Kong, Jieh-Yuan Liou, Chungming Chang, Yi-Chien Mau, Ming F. Tam, Andrew G. Brooks, Phillip E. Posch, Guochuan Tsai, King-Song Jeng, Sheue-Rong Lin, June-Nam Seah, Hwia-Cheng Ding
Publikováno v:
Journal of Biomedical Science. 5:395-399
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e876238721eabd5866acf33d94adc6b
https://doi.org/10.1159/000025353
https://doi.org/10.1159/000025353
Publikováno v:
Journal of Biological Chemistry. 271:10405-10412
A DNA response element, TR2RE-EPO (5′-TCTGACCTCTCGACCTAC-3′) has been identified in the 3′-minimal hypoxia-inducible enhancer of the human erythropoietin gene for the TR2 orphan receptor, an androgen-repressed transcription factor and a member
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98ba6a64de0ec67655605328f7a28aa
https://doi.org/10.1074/jbc.271.17.10405
https://doi.org/10.1074/jbc.271.17.10405
Publikováno v:
Chemistry and Physics of Lipids. 58:19-26
We report here the complete synthesis of the spin-labeled derivative of an antitumor ether phospholipid, 1- O -octadecyl-2- O -(4′-doxylpentyl- rac -glycerol-3-phosphocholine. This also represents the first time that the synthesis of a nitroxide sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13239c98237eca5994d5ddd4c260f4d
https://doi.org/10.1016/0009-3084(91)90107-m
https://doi.org/10.1016/0009-3084(91)90107-m