Výsledky vyhledávání - "Charles C. McOsker"

Akademický článek

Crumbling the Castle: Targeting DNABII Proteins for Collapsing Bacterial Biofilms as a Therapeutic Approach to Treat Disease and Combat Antimicrobial Resistance

Autor: James V. Rogers, Veronica L. Hall, Charles C. McOsker

Publikováno v: Antibiotics, Vol 11, Iss 1, p 104 (2022)

Antimicrobial resistance (AMR) is a concerning global threat that, if not addressed, could lead to increases in morbidity and mortality, coupled with societal and financial burdens. The emergence of AMR bacteria can be attributed, in part, to the dec

Externí odkaz: https://doaj.org/article/fffcaefa1698492f8ab5e53fe71bda3e

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Two novel paradigms for the simultaneous assessment of conditioned taste aversion and food intake effects of anorexic agents

Autor: Randy J. Seeley, Patrick Messerschmidt, Stephen C. Woods, Dawn M.M Eckstein, Karen M.B. Hodge, Charles C. McOsker, Kihmberly A. Wilmer, Russell James Sheldon, Melissa B. Jones, Stephen C. Benoit, Ellen L. Air

Publikováno v: Physiology & Behavior. 79:761-766

The conditioned taste aversion (CTA) is routinely used to assess the aversive consequences of anorexic agents, including potential pharmacological therapies for obesity. In a typical CTA paradigm, rats briefly sampling a novel tastant (e.g., sacchari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250b1923a164753c7e70afb3c6b40310
https://doi.org/10.1016/s0031-9384(03)00189-6

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Assessment of the aversive consequences of acute and chronic administration of the melanocortin agonist, MTII

Autor: Karen M.B. Hodge, Kihmberly A. Wilmer, Stephen C. Woods, Randy J. Seeley, Charles C. McOsker, P Messerschmidt, Ellen L. Air, Stephen C. Benoit, Melissa B. Jones, Russell James Sheldon, D M M Eckstein

Publikováno v: International Journal of Obesity. 27:550-556

BACKGROUND: The synthetic melanocortin (MC) agonist, melanotan-II (MTII), reduces food intake and body weight for hours to days after administration. One early report on the effect of MTII suggested that part of its anorexic action may be mediated by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec892f114f3f3ece95e499f9cc75dcc
https://doi.org/10.1038/sj.ijo.0802280

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Nitrofurantoin: Mechanism of action and implications for resistance development in common uropathogens

Autor: Charles C. McOsker, Penny M. Fitzpatrick

Publikováno v: Journal of Antimicrobial Chemotherapy. 33:23-30

Nitrofurantoin is an effective urinary tract antibacterial to which no clinically significant resistance development has occurred. We have previously shown that nitrofurantoin susceptibility in bacteria correlates with the presence of bacterial nitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c86a52c267a92c8b8ee9ff5da73d85
https://doi.org/10.1093/jac/33.suppl_a.23

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The effect of the melanocortin agonist, MT-II, on the defended level of body adiposity

Autor: Ofer Reizes, Russell James Sheldon, Melissa L. Burklow, Randy J. Seeley, Maria Claudia Gross, Darren Paul Trokhan, Colette C. Matthews, Kihmberly A. Wilmer, Charles C. McOsker

Publikováno v: Endocrinology. 146(9)

A wide range of experimental evidence implicates a critical role for melanocortin signaling in the control of food intake and body adiposity. Melanocortin receptor agonists such as MT-II potently reduce food intake and body weight, making such agonis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6504baa913fbc2c81f734796b7f3f9
https://pubmed.ncbi.nlm.nih.gov/15932932

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Silane reductions in acidic media. 10. Ionic hydrogenation of cycloalkenes. Stereoselectivity and mechanism

Autor: Michael P. Doyle, Charles C. McOsker

Publikováno v: The Journal of Organic Chemistry. 43:693-696

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02f85e8ee4a49e27929b4a5cd829ffc8
https://doi.org/10.1021/jo00398a039

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Silane reductions in acidic media. VII. Aluminum chloride catalyzed hydrogen-halogen exchange between organosilanes and alkyl halides. An efficient hydrocarbon synthesis

Autor: Charles C. McOsker, Charles T. West, Michael P. Doyle

Publikováno v: The Journal of Organic Chemistry. 41:1393-1396

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0473565798abd45f76e8c9192627736b
https://doi.org/10.1021/jo00870a022

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Silane reductions in acidic media

Autor: Stephen J. Donnelly, Charles C. McOsker, Michael P. Doyle, Charles T. West

Publikováno v: Journal of Organometallic Chemistry. 117:129-140

Aldehydes and ketones are selectively reduced by organosilanes in boron trifluoride etherate through a process in which boron trifluoride is consumed and fluorosilanes are formed. Reductions of aldehydes and ketones by triethylsilane produce, after h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10976d4700508207bfeb44092b487e7b
https://doi.org/10.1016/s0022-328x(00)87264-2

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