Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Charles C. Clark"'
Publikováno v:
Journal of Orthopaedic Research. 32:894-903
The objective of the described experiments was to determine the electrical parameters that lead to optimal expression of a number of bone-related genes in cultured human bone cells exposed to a capacitively coupled electric field. Human calvarial ost
Publikováno v:
Open Journal of Biophysics. :158-164
We have previously shown that capacitively coupled electrical stimulation of either normal bovine articular chondrocytes or osteoarthritic human articular cartilage explants resulted in up-regulation of cartilage matrix gene expression and down-regul
Publikováno v:
The Journal of Bone and Joint Surgery-American Volume. 90:833-848
Background: The destruction of cartilage in patients with osteoarthritis is a consequence of an imbalance between matrix synthesis and degradation. The purpose of the present study was to determine the effects of electrical stimulation on these proce
Publikováno v:
Biochemical and Biophysical Research Communications. 342:556-561
Electric stimulation has long been used as a tool to promote connective tissue healing, but the mechanism(s) by which this is accomplished are not yet known. We have previously determined, using mass cultures of fetal bovine articular chondrocytes, a
Autor:
Jay F. Custer, Charles C. Clark
Publikováno v:
North American Archaeologist. 24:29-81
A pit feature containing human remains was originally interpreted as a trash pit based on its shape, the presence of ceramic sherds, flakes, and fire-cracked rocks, and the absence of items traditionally viewed as “grave goods.” However, a cooper
Autor:
Charles C. Clark, Ward Churchill
Publikováno v:
North American Archaeologist. 21:249-288
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 32(7)
The objective of the described experiments was to determine the electrical parameters that lead to optimal expression of a number of bone-related genes in cultured human bone cells exposed to a capacitively coupled electric field. Human calvarial ost
Publikováno v:
Journal of Orthopaedic Research. 13:553-561
To investigate the influence of microvessel cells on osteoblasts, we exposed osteoblast-enriched cultures of rat calvarial cells to cultured endothelial cells and pericytes using feeder-layer co-cultures, co-culture dish inserts, and conditioned medi
Publikováno v:
Journal of Orthopaedic Research. 13:220-229
Longitudinal growth of bone involves a complex sequence of cellular events in the cartilaginous epiphysis. Whole blood serum has been shown previously to be a potent stimulus to the cells of the growth plate, as demonstrated by its ability to activat
Publikováno v:
Journal of Orthopaedic Research. 12:601-611
The calcium-mobilizing agents thapsigargin and 2,5-di-(tert-butyl)-1,4- benzohydroquinone were shown to markedly elevate the intracellular calcium concentration of chick embryo chondrocytes in a dose-dependent manner. Under these conditions, the meta