Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Charles C Berry"'
Autor:
Karen E Ocwieja, Troy L Brady, Keshet Ronen, Alyssa Huegel, Shoshannah L Roth, Torsten Schaller, Leo C James, Greg J Towers, John A T Young, Sumit K Chanda, Renate König, Nirav Malani, Charles C Berry, Frederic D Bushman
Publikováno v:
PLoS Pathogens, Vol 7, Iss 3, p e1001313 (2011)
Genome-wide siRNA screens have identified host cell factors important for efficient HIV infection, among which are nuclear pore proteins such as RanBP2/Nup358 and the karyopherin Transportin-3/TNPO3. Analysis of the roles of these proteins in the HIV
Externí odkaz:
https://doaj.org/article/f25183735b154f4b95512dccdb88946b
Autor:
Mary K Lewinski, Masahiro Yamashita, Michael Emerman, Angela Ciuffi, Heather Marshall, Gregory Crawford, Francis Collins, Paul Shinn, Jeremy Leipzig, Sridhar Hannenhalli, Charles C Berry, Joseph R Ecker, Frederic D Bushman
Publikováno v:
PLoS Pathogens, Vol 2, Iss 6, p e60 (2006)
Retroviruses differ in their preferences for sites for viral DNA integration in the chromosomes of infected cells. Human immunodeficiency virus (HIV) integrates preferentially within active transcription units, whereas murine leukemia virus (MLV) int
Externí odkaz:
https://doaj.org/article/085421e974b14733afd1f0c13871433f
Autor:
Rick S Mitchell, Brett F Beitzel, Astrid R W Schroder, Paul Shinn, Huaming Chen, Charles C Berry, Joseph R Ecker, Frederic D Bushman
Publikováno v:
PLoS Biology, Vol 2, Iss 8, p E234 (2004)
The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA integration. Here we report an analysis of 3,127 integration site sequences from human cells. We compared retroviral vectors derived from human immuno
Externí odkaz:
https://doaj.org/article/115fed14a9964586a86f48acdc037db3
Publikováno v:
Mol Ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040262a199965336969ee33b21b0c211
https://doi.org/10.1016/j.ymthe.2021.10.022
https://doi.org/10.1016/j.ymthe.2021.10.022
Autor:
Hannah O. Ajoge, Hinissan P. Kohio, Ermela Paparisto, Macon D. Coleman, Kemen Wong, Sean K. Tom, Katie L. Bain, Charles C. Berry, Eric J. Arts, Stephen D. Barr
Publikováno v:
Viruses; Volume 14; Issue 11; Pages: 2494
Viruses, vol 14, iss 11
Viruses, vol 14, iss 11
The integration of the HIV-1 genome into the host genome is an essential step in the life cycle of the virus and it plays a critical role in the expression, long-term persistence, and reactivation of HIV expression. To better understand the local gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74000ccc714f85ea84ed424b8105ed0c
https://doi.org/10.3390/v14112494
https://doi.org/10.3390/v14112494
Autor:
Anatoly Dryga, Emmanuelle Six, Yinghua Wu, Mary Jane Drake, Christopher L. Nobles, Eric J. Sherman, Aubrey Bailey, Laure Caccavelli, Nirav Malani, Paul Bates, Salima Hacein-Bey-Abina, Frances Male, Frederic D. Bushman, Shantan Reddy, Marina Cavazzana, Charles C. Berry, John K. Everett, Kyle Bittinger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 4, Iss C, Pp 39-49 (2017)
Molecular Therapy. Methods & Clinical Development
Sherman, E; Nobles, C; Berry, CC; Six, E; Wu, Y; Dryga, A; et al.(2017). INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes. MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 4, 39-49. doi: 10.1016/j.omtm.2016.11.002. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2tq50500
Molecular Therapy. Methods & Clinical Development
Sherman, E; Nobles, C; Berry, CC; Six, E; Wu, Y; Dryga, A; et al.(2017). INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes. MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 4, 39-49. doi: 10.1016/j.omtm.2016.11.002. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2tq50500
Integration of new DNA into cellular genomes mediates replication of retroviruses and transposons; integration reactions have also been adapted for use in human gene therapy. Tracking the distributions of integration sites is important to characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbdf7982cad42256726d2cbc46a1b137
http://www.sciencedirect.com/science/article/pii/S2329050116301309
http://www.sciencedirect.com/science/article/pii/S2329050116301309
Autor:
Nirav Malani, Aubrey Bailey, Kyle Bittinger, Salima Hacein-Bey-Abina, Frances Male, Marina Cavazzana, Charles C. Berry, Laure Caccavelli, Frederic D. Bushman, Mary Jane Drake, Emmanuelle Six, Yinghua Wu, Paul Bates, Christopher L. Nobles, Eric J. Sherman, Anatoly Dryga, John K. Everett
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 4, Iss C, Pp 17-26 (2017)
Berry, CC; Nobles, C; Six, E; Wu, Y; Malani, N; Sherman, E; et al.(2017). INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions. MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 4, 17-26. doi: 10.1016/j.omtm.2016.11.003. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1z88x22p
Molecular Therapy: Methods & Clinical Development, Vol 4, Iss C, Pp 17-26 (2017)
Berry, CC; Nobles, C; Six, E; Wu, Y; Malani, N; Sherman, E; et al.(2017). INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions. MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 4, 17-26. doi: 10.1016/j.omtm.2016.11.003. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1z88x22p
Analysis of sites of newly integrated DNA in cellular genomes is important to several fields, but methods for analyzing and visualizing these datasets are still under development. Here, we describe tools for data analysis and visualization that take
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c22c2aa171def36fc0e67010770679
https://pubmed.ncbi.nlm.nih.gov/28344988
https://pubmed.ncbi.nlm.nih.gov/28344988
Autor:
Anat Melamed, Nicolas Gillet, Niall Anthony Gormley, Charles R. M. Bangham, Frederic D. Bushman, Charles C. Berry
Publikováno v:
Bioinformatics. 28:755-762
Motivation: The relative abundance of retroviral insertions in a host genome is important in understanding the persistence and pathogenesis of both natural retroviral infections and retroviral gene therapy vectors. It could be estimated from a sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdde78dd0e9a9ba098282d3a9a7199fc
https://doi.org/10.1093/bioinformatics/bts004
https://doi.org/10.1093/bioinformatics/bts004
Autor:
Charles C. Berry, Anat Melamed, Frederic D. Bushman, Nirav Malani, Richard J. Carter, Graham P. Taylor, Nicolas Gillet, Charles R. M. Bangham, David Bentley, Niall Anthony Gormley
Publikováno v:
Blood. 117:3113-3122
Human T-lymphotropic virus type 1 (HTLV-1) persists by driving clonal proliferation of infected T lymphocytes. A high proviral load predisposes to HTLV-1–associated diseases. Yet the reasons for the variation within and between persons in the abund
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69aaca964b56f164271617f51d142bca
https://doi.org/10.1182/blood-2010-10-312926
https://doi.org/10.1182/blood-2010-10-312926
Autor:
Lily E. Leiva, Frédéric Rieux-Laucat, Julia Hauer, Bernd H. Belohradsky, Jean-Laurent Casanova, Gary P. Wang, Stéphane Blanche, Marianne Debré, Marina Cavazzana-Calvo, Chantal Martinache, Anne Durandy, Sylvain Latour, Ricardo U. Sorensen, Annick Lim, Capucine Picard, Alain Fischer, Salima Hacein-Bey-Abina, Frederic D. Bushman, Charles C. Berry
Publikováno v:
New England Journal of Medicine. 363:355-364
Background The outcomes of gene therapy to correct congenital immunodeficiencies are unknown. We reviewed long-term outcomes after gene therapy in nine patients with X-linked severe combined immunodeficiency (SCID-X1), which is characterized by the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6e2145501cf6932d82a1f74c046c14
https://doi.org/10.1056/nejmoa1000164
https://doi.org/10.1056/nejmoa1000164