Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Charles C Bailey"'
Autor:
Huihui Mou, Brian D Quinlan, Haiyong Peng, Guanqun Liu, Yan Guo, Shoujiao Peng, Lizhou Zhang, Meredith E Davis-Gardner, Matthew R Gardner, Gogce Crynen, Lindsey B DeVaux, Zhi Xiang Voo, Charles C Bailey, Michael D Alpert, Christoph Rader, Michaela U Gack, Hyeryun Choe, Michael Farzan
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009501 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein mediates infection of cells expressing angiotensin-converting enzyme 2 (ACE2). ACE2 is also the viral receptor of SARS-CoV (SARS-CoV-1), a related coronavirus that eme
Externí odkaz:
https://doaj.org/article/98e83cef2acb4c9d893d3ecb82c4b632
Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells
Publikováno v:
eLife, Vol 5 (2016)
Efforts to control mammalian gene expression with ligand-responsive riboswitches have been hindered by lack of a general method for generating efficient switches in mammalian systems. Here we describe a rational-design approach that enables rapid dev
Externí odkaz:
https://doaj.org/article/c5dce78ff0b6475ab870f0662adc078e
Publikováno v:
PLoS Pathogens, Vol 8, Iss 9, p e1002909 (2012)
Interferon-induced transmembrane (IFITM) proteins are a family of viral restriction factors that inhibit the entry processes of several pathogenic viruses, including influenza A virus (IAV), in vitro. Here we report that IAV-infected knockout mice la
Externí odkaz:
https://doaj.org/article/cea9152cd499429cb319be41c8b827d3
Autor:
I-Chueh Huang, Charles C Bailey, Jessica L Weyer, Sheli R Radoshitzky, Michelle M Becker, Jessica J Chiang, Abraham L Brass, Asim A Ahmed, Xiaoli Chi, Lian Dong, Lindsay E Longobardi, Dutch Boltz, Jens H Kuhn, Stephen J Elledge, Sina Bavari, Mark R Denison, Hyeryun Choe, Michael Farzan
Publikováno v:
PLoS Pathogens, Vol 7, Iss 1, p e1001258 (2011)
Interferon-inducible transmembrane proteins 1, 2, and 3 (IFITM1, 2, and 3) are recently identified viral restriction factors that inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. Here we show that IFITM proteins r
Externí odkaz:
https://doaj.org/article/32c1e55b700c48ae8fdacde354b2f707
Autor:
Heather M. Callaway, Kathryn M. Hastie, Sharon L. Schendel, Haoyang Li, Xiaoying Yu, Jeremy Shek, Tierra Buck, Sean Hui, Dan Bedinger, Camille Troup, S. Moses Dennison, Kan Li, Michael D. Alpert, Charles C. Bailey, Sharon Benzeno, Jody L. Bonnevier, Jin-Qiu Chen, Charm Chen, Hyeseon Cho, Peter D. Crompton, Vincent Dussupt, Kevin C. Entzminger, Yassine Ezzyat, Jonathan K. Fleming, Nick Geukens, Amy E. Gilbert, Yongjun Guan, Xiaojian Han, Christopher J. Harvey, Julia M. Hatler, Bryan Howie, Chao Hu, Ailong Huang, Maya Imbrechts, Aishun Jin, Nik Kamachi, Gladys Keitany, Mark Klinger, Jay K. Kolls, Shelly J. Krebs, Tingting Li, Feiyan Luo, Toshiaki Maruyama, Michael A. Meehl, Letzibeth Mendez-Rivera, Andrea Musa, C.J. Okumura, Benjamin E.R. Rubin, Aaron K. Sato, Meiying Shen, Anirudh Singh, Shuyi Song, Joshua Tan, Jeffrey M. Trimarchi, Dhruvkumar P. Upadhyay, Yingming Wang, Lei Yu, Tom Z. Yuan, Erik Yusko, Bjoern Peters, Georgia Tomaras, Erica Ollmann Saphire
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112014- (2023)
Summary: The SARS-CoV-2 Omicron variant of concern (VoC) and its sublineages contain 31–36 mutations in spike and escape neutralization by most therapeutic antibodies. In a pseudovirus neutralization assay, 66 of the nearly 400 candidate therapeuti
Externí odkaz:
https://doaj.org/article/61e61f138daa45d1ba9a2edb473cf0bc
Autor:
Wenhui He, Tianling Ou, Nickolas Skamangas, Charles C. Bailey, Naomi Bronkema, Yan Guo, Yiming Yin, Valerie Kobzarenko, Xia Zhang, Andi Pan, Xin Liu, Ava E. Allwardt, Debasis Mitra, Brian Quinlan, Rogier W. Sanders, Hyeryun Choe, Michael Farzan
SUMMARYV2-glycan/apex broadly neutralizing antibodies (bnAbs) recognize a closed quaternary epitope of the HIV-1 envelope glycoprotein (Env). This closed structure is necessary to elicit apex antibodies and useful to guide maturation of other bnAb cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9973b1c5802667f29c7af056373e7463
https://doi.org/10.1101/2022.11.07.515497
https://doi.org/10.1101/2022.11.07.515497
Autor:
Hyeryun Choe, Mark A. Kay, Cody B. Jackson, Jeffrey M. Trimarchi, Kimberly A. Conkright, Audrey S. Richard, Charles C. Bailey, Amrita Ojha, Michael Farzan, Michael D. Alpert
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 496-506 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Adeno-associated virus (AAV) is one of the most commonly used vectors for gene therapy, and the applications for AAV-delivered therapies are numerous. However, the current state of technology is limited by the low efficiency with which most AAV vecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c4e17ebc85c2e8dee91075c3ff26fe
http://www.sciencedirect.com/science/article/pii/S232905012030231X
http://www.sciencedirect.com/science/article/pii/S232905012030231X
Autor:
Audrey C Knight, Suzanne E. Queen, Joseph L. Mankowski, Clarisse V. Solis, Morgan R. Richardson, Charles C. Bailey, Megan E. McCarron, Samuel A. Brill
Publikováno v:
J Neurovirol
HIV-associated neuroinflammation is primarily driven by CNS macrophages including microglia. Regulation of these immune responses, however, remains to be characterized in detail. Using the SIV/macaque model of HIV, we evaluated CNS expression of trig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ab7f339ed006f42ca19e8391941f78
https://doi.org/10.1007/s13365-020-00844-1
https://doi.org/10.1007/s13365-020-00844-1
Autor:
Lizhou Zhang, Michaela U. Gack, Charles C. Bailey, GuanQun Liu, Meredith E. Davis-Gardner, Huihui Mou, Hyeryun Choe, Christoph Rader, Zhi Xiang Voo, Haiyong Peng, Michael D. Alpert, Gogce Crynen, Michael Farzan, Matthew R. Gardner, Shoujiao Peng, Lindsey B. DeVaux, Brian D. Quinlan, Yan Guo
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009501 (2021)
PLoS Pathogens
bioRxiv
article-version (status) pre
article-version (number) 1
PLoS Pathogens
bioRxiv
article-version (status) pre
article-version (number) 1
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein mediates infection of cells expressing angiotensin-converting enzyme 2 (ACE2). ACE2 is also the viral receptor of SARS-CoV (SARS-CoV-1), a related coronavirus that eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba257fb110ab5f74b0edaa482f0ee052
https://doaj.org/article/98e83cef2acb4c9d893d3ecb82c4b632
https://doaj.org/article/98e83cef2acb4c9d893d3ecb82c4b632
Autor:
Ritu Khare, Michael D. Kappelman, Charles Samson, Jennifer Pyrzanowski, Rahul A. Darwar, Christopher B. Forrest, Charles C. Bailey, Peter Margolis, Amanda Dempsey, And the PEDSnet Computable Phenotype Working Group
Publikováno v:
Learning Health Systems, Vol 4, Iss 4, Pp n/a-n/a (2020)
Learning Health Systems
Learning Health Systems
Objectives To develop and evaluate the classification accuracy of a computable phenotype for pediatric Crohn's disease using electronic health record data from PEDSnet, a large, multi‐institutional research network and Learning Health System. Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d857adaf2130a46b55845104fe2b186
https://doaj.org/article/114bacda78394e348d61ca9cdaf7852b
https://doaj.org/article/114bacda78394e348d61ca9cdaf7852b