Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Charles Bridgewood"'
Autor:
Dennis G McGonagle, Nathan J Dean, Ian J Clifton, Rashad Salman, Charles Bridgewood, Jacquie Nam, Tom Macleod
Publikováno v:
RMD Open, Vol 9, Iss 4 (2023)
Objective The increasing use of biological therapies has led to the paradoxical finding that monoclonal antibody therapy for one inflammatory disease can sometimes induce another inflammatory disease. Recently, the use of anti-IL-5 (IL, interleukin)
Externí odkaz:
https://doaj.org/article/0707d3cec695420b8515530013984e4a
Autor:
Zheni Stavre, Charles Bridgewood, Qiao Zhou, Yukiko Maeda, Ting-ting Huang, Jozsef Karman, Almas Khan, Sami Giryes, Kassem Sharif, Dennis McGonagle, Ellen M. Gravallese
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-11 (2022)
Abstract Background Neutrophils are present in the early phases of spondyloarthritis-related uveitis, skin and intestinal disease, but their role in enthesitis, a cardinal musculoskeletal lesion in spondyloarthritis, remains unknown. We considered th
Externí odkaz:
https://doaj.org/article/36408da6ee8a44e39ba760c7db29e01f
Publikováno v:
The Lancet Rheumatology. 5:e47-e57
Autor:
Tom Macleod, Charles Bridgewood, Isabel Hyde, Megan Heague, Philip Helliwell, Martin Stacey, Miriam Wittmann
Publikováno v:
Clinical Science. 136:935-952
This review highlights the molecular and cellular mechanisms underlying psoriatic inflammation with an emphasis on recent developments which may impact on treatment approaches for this chronic disease. We consider both the skin and the musculoskeleta
Publikováno v:
Stroke. 53(7)
The main burden of SARS-CoV-2 falls on the lungs but neurological manifestations, the most disabling of which are strokes and which correlate with disease severity, are common. We proffer a novel mechanism for acute COVID-19 stroke whereby pulmonary
Publikováno v:
Seminars in immunopathology. 44(3)
The SARS-CoV-2 virus ACE-2 receptor utilization for cellular entry and the defined ACE-2 receptor role in cardiovascular medicine hinted at dysregulated endothelial function or even direct viral endotheliitis as the key driver of severe COVID-19 vasc
Autor:
Dennis McGonagle, Mary F Kearney, Anthony O'Regan, James S O'Donnell, Luca Quartuccio, Abdulla Watad, Charles Bridgewood
Publikováno v:
The Lancet. Rheumatology
In patients with moderate-to-severe COVID-19 pneumonia, an aberrant post-viral alveolitis with excessive inflammatory responses and immunothrombosis underpins use of immunomodulatory therapy (eg, corticosteroids and interleukin-6 receptor antagonism)
Autor:
Zheni Stavre, Charles Bridgewood, Qiao Zhou, Yukiko Maeda, Ting-ting Huang, Jozsef Karman, Almas Khan, Sami Giryes, Kassem Sharif, Dennis McGonagle, Ellen M. Gravallese
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-11 (2022)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background Neutrophils are present in the early phases of spondyloarthritis-related uveitis, skin and intestinal disease, but their role in enthesitis, a cardinal musculoskeletal lesion in spondyloarthritis, remains unknown. We considered the role of
Publikováno v:
The Lancet Rheumatology. 4:e173