Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Charles Bou-Nader"'
Autor:
Cesar Valencia-Gallardo, Daniel-Isui Aguilar-Salvador, Hamed Khakzad, Benjamin Cocom-Chan, Charles Bou-Nader, Christophe Velours, Yosra Zarrouk, Christophe Le Clainche, Christian Malosse, Diogo Borges Lima, Nicole Quenech’Du, Bilal Mazhar, Sami Essid, Marc Fontecave, Atef Asnacios, Julia Chamot-Rooke, Lars Malmström, Guy Tran Van Nhieu
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112405- (2023)
Summary: Upon activation, vinculin reinforces cytoskeletal anchorage during cell adhesion. Activating ligands classically disrupt intramolecular interactions between the vinculin head and tail domains that bind to actin filaments. Here, we show that
Externí odkaz:
https://doaj.org/article/c7264a6cb8d84810a58eacb247fd705e
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The S9.6 monoclonal antibody is widely used to map R-loops genome wide. Here, Bou-Nader et al., define the nucleic acid-binding specificity of S9.6 and report its crystal structures free and bound to a hybrid, which reveal the asymmetric recognition
Externí odkaz:
https://doaj.org/article/72b7f5732f7c4a07a879fd125d37cd1f
Autor:
Charles Bou-Nader, Frederick W. Stull, Ludovic Pecqueur, Philippe Simon, Vincent Guérineau, Antoine Royant, Marc Fontecave, Murielle Lombard, Bruce A. Palfey, Djemel Hamdane
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
The bacterial thymidylate synthase ThyX catalyzes the reductive methylation of deoxyuridylate (dUMP) into deoxythymidylate (dTMP) and requires both folate and flavin for activity. Here, the authors combine biochemical experiments, spectroscopic measu
Externí odkaz:
https://doaj.org/article/9d2804fa1f2e4892889a444777040660
Autor:
Charles Bou-Nader, Jinwei Zhang
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101056- (2022)
Summary: Host tRNAs specifically interact with the matrix domain (MA) of HIV-1 major structural polyprotein, Gag, to control its membrane localization and virion assembly. In this protocol, we describe the purification and engineering of HIV-1 MA and
Externí odkaz:
https://doaj.org/article/f65cdde6734b4dc580d33495f6688ef6
Autor:
Iris V. Hood, Jackson M. Gordon, Charles Bou-Nader, Frances E. Henderson, Soheila Bahmanjah, Jinwei Zhang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Adenovirus Virus-Associated (VA) noncoding RNAs interfere with the host system by mimicking double stranded RNAs. Here, the authors report a 2.7 Å crystal structure of VA-I RNA providing an understanding of its function.
Externí odkaz:
https://doaj.org/article/f3f53fac7850403e943a110a17e01938
Autor:
Charles Bou-Nader, Jinwei Zhang
Publikováno v:
Molecules, Vol 25, Iss 12, p 2881 (2020)
In comparison with the pervasive use of protein dimers and multimers in all domains of life, functional RNA oligomers have so far rarely been observed in nature. Their diminished occurrence contrasts starkly with the robust intrinsic potential of RNA
Externí odkaz:
https://doaj.org/article/0b07b2f0919e4d92b2e4e823103ade07
Autor:
Cesar Valencia-Gallardo, Daniel-Isui Aguilar-Salvador, Hamed Khakzad, Benjamin Cocom-Chan, Charles Bou-Nader, Christophe Velours, Yosra Zarrouk, Christophe Le Clainche, Christian Malosse, Diogo Borges Lima, Nicole Quenech’Du, Bilal Mazhar, Sami Essid, Marc Fontecave, Atef Asnacios, Julia Chamot-Rooke, Lars Malmström, Guy Tran Van Nhieu
Upon activation, vinculin reinforces cytoskeletal anchorage during cell adhesion. Activating ligands classically disrupt intramolecular interactions between the vinculin head and tail domain that binds to actin filaments. Here, we show thatShigellaIp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f49da36b25d4ce270d6d7a3c42dc5fc
https://doi.org/10.1101/2022.11.07.515412
https://doi.org/10.1101/2022.11.07.515412
Autor:
Jinwei Zhang, Charles Bou-Nader
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101056-(2022)
STAR Protocols
STAR Protocols
Summary Host tRNAs specifically interact with the matrix domain (MA) of HIV-1 major structural polyprotein, Gag, to control its membrane localization and virion assembly. In this protocol, we describe the purification and engineering of HIV-1 MA and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536edfd9c0aadefee6d66d4dc3581f45
https://pubmed.ncbi.nlm.nih.gov/35005638
https://pubmed.ncbi.nlm.nih.gov/35005638
Publikováno v:
Nature communications. 13(1)
R-loops are ubiquitous, dynamic nucleic-acid structures that play fundamental roles in DNA replication and repair, chromatin and transcription regulation, as well as telomere maintenance. The DNA-RNA hybrid–specific S9.6 monoclonal antibody is wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc321d6a3d2cf02e013e91ff5a82d081
https://pubmed.ncbi.nlm.nih.gov/35347133
https://pubmed.ncbi.nlm.nih.gov/35347133
Publikováno v:
RNA. 25:539-556
The interferon-inducible protein kinase R (PKR) is a key component of host innate immunity that restricts viral replication and propagation. As one of the four eIF2α kinases that sense diverse stresses and direct the integrated stress response (ISR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abe3f58a09d9508ff2ad4dfc78aa6c9
https://doi.org/10.1261/rna.070169.118
https://doi.org/10.1261/rna.070169.118