Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Charles B. Epstein"'
Autor:
Youngsook Lucy Jung, Wenping Zhao, Ian Li, Dhawal Jain, Charles B. Epstein, Bradley E. Bernstein, Sareh Parangi, Richard Sherwood, Cassianne Robinson-Cohen, Yi-Hsiang Hsu, Peter J. Park, Michael Mannstadt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract In all terrestrial vertebrates, the parathyroid glands are critical regulators of calcium homeostasis and the sole source of parathyroid hormone (PTH). Hyperparathyroidism and hypoparathyroidism are clinically important disorders affecting m
Externí odkaz:
https://doaj.org/article/fdbabb7074f14e289e86632096973964
Autor:
Nauman Javed, Yossi Farjoun, Tim J. Fennell, Charles B. Epstein, Bradley E. Bernstein, Noam Shoresh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Parallelized analysis in clinical genomics can lead to sample or data mislabelling, and could have serious downstream consequences. Here the authors present a tool to quantify sample genetic relatedness and detect such mistakes, and apply it to thous
Externí odkaz:
https://doaj.org/article/3aac3ad4af5c44bbbcff502de0819ea0
Autor:
Bradley E. Bernstein, Ephraim P. Hochberg, Aliyah R. Sohani, Valentina Nardi, Charles B. Epstein, Shawn Gillespie, Robbyn Issner, Jasleen Kaur, M. Joel Cotton, Holly Whitton, Yotam Drier, Russell J.H. Ryan
Supplementary Table S1. Clinical and diagnostic information on lymphoma cases. Supplementary Table S2. Rearrangements detected by PEAR-ChIP in 14 lymphoma primary samples and 8 lymphoma cell lines. Supplementary Table S3. Detection of large-scale rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b019fe6ebc031d5b755dad88ed22bb
https://doi.org/10.1158/2159-8290.22529937
https://doi.org/10.1158/2159-8290.22529937
Autor:
Bradley E. Bernstein, Ephraim P. Hochberg, Aliyah R. Sohani, Valentina Nardi, Charles B. Epstein, Shawn Gillespie, Robbyn Issner, Jasleen Kaur, M. Joel Cotton, Holly Whitton, Yotam Drier, Russell J.H. Ryan
Supplementary Figure S1. H3K27ac ChIP-Seq tracks and position of rearrangements of possible oncogenic significance detected by PEAR-ChIP. Red bars join discordant intra-chromosomal read pairs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900fa1aa5c257675d713a4d2e2b6f25e
https://doi.org/10.1158/2159-8290.22529955.v1
https://doi.org/10.1158/2159-8290.22529955.v1
Autor:
Bradley E. Bernstein, Ephraim P. Hochberg, Aliyah R. Sohani, Valentina Nardi, Charles B. Epstein, Shawn Gillespie, Robbyn Issner, Jasleen Kaur, M. Joel Cotton, Holly Whitton, Yotam Drier, Russell J.H. Ryan
Supplementary Methods, Figure Legends, Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bed27b2d1ea518a8548f0942f974d8
https://doi.org/10.1158/2159-8290.22529940.v1
https://doi.org/10.1158/2159-8290.22529940.v1
Autor:
Bradley E. Bernstein, Ephraim P. Hochberg, Aliyah R. Sohani, Valentina Nardi, Charles B. Epstein, Shawn Gillespie, Robbyn Issner, Jasleen Kaur, M. Joel Cotton, Holly Whitton, Yotam Drier, Russell J.H. Ryan
Supplementary Table S4. Sequences of oligonucleotides used for qRT-PCR, RT-PCR, and 3C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210e5fa223cb63f4621df3127adc77c8
https://doi.org/10.1158/2159-8290.22529934
https://doi.org/10.1158/2159-8290.22529934
Autor:
Yan Hu, Sai Ma, Vinay K. Kartha, Fabiana M. Duarte, Max Horlbeck, Ruochi Zhang, Rojesh Shrestha, Ajay Labade, Heidi Kletzien, Alia Meliki, Andrew Castillo, Neva Durand, Eugenio Mattei, Lauren J. Anderson, Tristan Tay, Andrew S. Earl, Noam Shoresh, Charles B. Epstein, Amy Wagers, Jason D. Buenrostro
Publikováno v:
bioRxiv
Cis-regulatory elements control gene expression and are dynamic in their structure, reflecting changes to the composition of diverse effector proteins over time1–3. Here we sought to connect the structural changes atcis-regulatory elements to alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01513d689bd91b82e69e1dffb348ebb
https://europepmc.org/articles/PMC10081223/
https://europepmc.org/articles/PMC10081223/
Autor:
Yao Yao, Jessica Fong Ng, Woojun Daniel Park, Mehmet K. Samur, Eugenio Morelli, Jessica Encinas, Zuzana Chyra, Yan Xu, Sanika Derebail, Charles B. Epstein, Behnam Nabet, Marta Chesi, Nathanael S Gray, Richard Young, Nicholas Kwiatkowski, Constantine S. Mitsiades, Kenneth C. Anderson, Charles Y. Lin, Nikhil C. Munshi, Mariateresa Fulciniti
Publikováno v:
Blood.
Therapeutic targeting of CDK7 has proven beneficial in pre-clinical studies, yet the off-target effects of currently available CDK7 inhibitors make it difficult to pinpoint the exact mechanisms behind MM cell death mediated by CDK7 inhibition. Here,
Autor:
Joel Rozowsky, Jiahao Gao, Beatrice Borsari, Yucheng T. Yang, Timur Galeev, Gamze Gürsoy, Charles B. Epstein, Kun Xiong, Jinrui Xu, Tianxiao Li, Jason Liu, Keyang Yu, Ana Berthel, Zhanlin Chen, Fabio Navarro, Maxwell S. Sun, James Wright, Justin Chang, Christopher J.F. Cameron, Noam Shoresh, Elizabeth Gaskell, Jorg Drenkow, Jessika Adrian, Sergey Aganezov, François Aguet, Gabriela Balderrama-Gutierrez, Samridhi Banskota, Guillermo Barreto Corona, Sora Chee, Surya B. Chhetri, Gabriel Conte Cortez Martins, Cassidy Danyko, Carrie A. Davis, Daniel Farid, Nina P. Farrell, Idan Gabdank, Yoel Gofin, David U. Gorkin, Mengting Gu, Vivian Hecht, Benjamin C. Hitz, Robbyn Issner, Yunzhe Jiang, Melanie Kirsche, Xiangmeng Kong, Bonita R. Lam, Shantao Li, Bian Li, Xiqi Li, Khine Zin Lin, Ruibang Luo, Mark Mackiewicz, Ran Meng, Jill E. Moore, Jonathan Mudge, Nicholas Nelson, Chad Nusbaum, Ioann Popov, Henry E. Pratt, Yunjiang Qiu, Srividya Ramakrishnan, Joe Raymond, Leonidas Salichos, Alexandra Scavelli, Jacob M. Schreiber, Fritz J. Sedlazeck, Lei Hoon See, Rachel M. Sherman, Xu Shi, Minyi Shi, Cricket Alicia Sloan, J Seth Strattan, Zhen Tan, Forrest Y. Tanaka, Anna Vlasova, Jun Wang, Jonathan Werner, Brian Williams, Min Xu, Chengfei Yan, Lu Yu, Christopher Zaleski, Jing Zhang, Kristin Ardlie, J Michael Cherry, Eric M. Mendenhall, William S. Noble, Zhiping Weng, Morgan E. Levine, Alexander Dobin, Barbara Wold, Ali Mortazavi, Bing Ren, Jesse Gillis, Richard M. Myers, Michael P. Snyder, Jyoti Choudhary, Aleksandar Milosavljevic, Michael C. Schatz, Bradley E. Bernstein, Roderic Guigó, Thomas R. Gingeras, Mark Gerstein
Understanding how genetic variants impact molecular phenotypes is a key goal of functional genomics, currently hindered by reliance on a single haploid reference genome. Here, we present the EN-TEx resource of 1,635 open-access datasets from four don
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464939170ba93b49ee4e474d325702f1
http://hdl.handle.net/10230/56942
http://hdl.handle.net/10230/56942
Autor:
Tomokazu S. Sumida, Matthew R. Lincoln, Liang He, Yongjin Park, Mineto Ota, Helen A. Stillwell, Greta A. Leissa, Keishi Fujio, Alexander M. Kulminski, Charles B. Epstein, Bradley E. Bernstein, Manolis Kellis, David A. Hafler
Autoimmune diseases, among the most common disorders of young adults, are mediated by genetic and environmental factors. While CD4+Foxp3+regulatory T cells (Tregs) play a central role in preventing autoimmunity, the molecular mechanism underlying the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7b18add77bf4924b98ce2e9c66a1abd
https://doi.org/10.1101/2022.12.02.518871
https://doi.org/10.1101/2022.12.02.518871