Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Charles B, Malpas"'
Autor:
Tomas Kalincik, Charles B Malpas, Michael Dickinson, Izanne Roos, Stefanie Roberts, Samantha M Loi, Mark Dowling, Carmela Sales, Fiore D’Aprano, Valeriya Kuznetsova, Harsh Oza, Hannah Rosenfeld, Samantha van der Linde, Simon J Harrison, Mary Ann Anderson
Publikováno v:
BMJ Neurology Open, Vol 6, Iss 2 (2024)
Introduction Immune effector cell-associated neurotoxicity syndrome (ICANS) is a common side-effect of chimeric antigen receptor T-cell (CAR-T) therapy, with symptoms ranging from mild to occasionally life-threatening. The neurological, cognitive, ps
Externí odkaz:
https://doaj.org/article/77fbcbb4426d477e8b59a88ae23e1602
Autor:
Roxane Dilcher, Charles B. Malpas, Mark Walterfang, Dennis Velakoulis, Terence J. O’Brien, Lucy Vivash
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
In a large proportion of individuals with fronto-temporal lobar degeneration (FTLD), the underlying pathology is associated with the misfolding and aggregation of the microtubule associated protein tau (FTLD-tau). With disease progression, widespread
Externí odkaz:
https://doaj.org/article/4a70ce61ec5547999ad2a0fa8a0b34dd
Autor:
Nicholas M. Burgess, Wendy Kelso, Charles B. Malpas, Toby Winton-Brown, Timothy Fazio, Julie Panetta, Gerard De Jong, Joanna Neath, Sonny Atherton, Dennis Velakoulis, Mark Walterfang
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-8 (2021)
Abstract Background Phenylketonuria (PKU) is an autosomal recessive inherited disorder characterised by a deficiency in phenylalanine hydroxylase. Untreated, PKU is associated with a wide range of cognitive and psychiatric sequelae. Contemporary mana
Externí odkaz:
https://doaj.org/article/461833f33f574b35a09a446f56ee377f
Autor:
Lucy Vivash, Charles B. Malpas, Christian Meletis, Meghan Gollant, Dhamidhu Eratne, Qiao‐Xin Li, Stuart McDonald, William T. O'Brien, Amy Brodtmann, David Darby, Christopher Kyndt, Mark Walterfang, Christopher M. Hovens, Dennis Velakoulis, Terence J. O'Brien
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Sodium selenate increases tau dephosphorylation through protein phosphatase 2 activation. Here we report an open‐label Phase 1b study of sodium selenate as a disease‐modifying treatment for behavioral variant frontotemporal
Externí odkaz:
https://doaj.org/article/2208b7c2a982408199bac2e4e96fdce6
Autor:
Howard Chiu, Sila Genc, Charles B. Malpas, Emma Sciberras, Jan M. Nicholson, Daryl Efron, Timothy J. Silk
Publikováno v:
Brain Disorders, Vol 4, Iss , Pp 100023- (2021)
Children with attention-deficit/hyperactivity disorder (ADHD) have poor academic functioning compared to typically developing children, with executive dysfunction mediating the relationship between ADHD symptoms and academic outcomes. This study inve
Externí odkaz:
https://doaj.org/article/01ddab4c75f0434aa307caeec4a7fcff
Autor:
Lucy Vivash, Dennis Velakoulis, Terence J O’Brien, Charles B Malpas, Amy Brodtmann, Christopher M Hovens, Steven Collins, Stephen Macfarlane
Publikováno v:
BMJ Neurology Open, Vol 3, Iss 2 (2021)
Introduction Sodium selenate is a potential disease-modifying treatment for Alzheimer’s disease (AD) which reduces hyperphosphorylated tau through activation of the protein phosphatase 2A enzyme. We have shown sodium selenate to be safe and well to
Externí odkaz:
https://doaj.org/article/c635a5b7fee8411fa1aea2b913960bf3
Autor:
Steve Vucic, Jeannette Lechner-Scott, Mark Slee, Suzanne Hodgkinson, Ernest Butler, Helmut Butzkueven, Michael Barnett, Richard Macdonell, Anneke Van Der Walt, Charles B Malpas, Pamela McCombe, Emmanuelle Leray, Sandra Vukusic, Izanne Roos, Katherine Buzzard, Olga Skibina
Publikováno v:
BMJ Neurology Open, Vol 3, Iss Suppl 1 (2021)
Externí odkaz:
https://doaj.org/article/3c6de0ac44244691b7848dfd5bb9d135
Publikováno v:
Journal of Alzheimer's Disease. :1-20
Behavioral variant frontotemporal dementia (bvFTD) belongs to the spectrum of frontotemporal lobar degeneration (FTLD) and is characterized by frontal dysfunction with executive deficits and prominent socio-emotional impairments. Social cognition, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53fed7bc19dba8e3041e1457a84dc0f0
https://doi.org/10.3233/jad-221171
https://doi.org/10.3233/jad-221171
Autor:
Matthew J. Y. Kang, Dhamidhu Eratne, Hannah Dobson, Charles B. Malpas, Michael Keem, Courtney Lewis, Jasleen Grewal, Vivian Tsoukra, Christa Dang, Ramon Mocellin, Tomas Kalincik, Alexander F. Santillo, Henrik Zetterberg, Kaj Blennow, Christiane Stehmann, Shiji Varghese, Qiao-Xin Li, Colin L. Masters, Steven Collins, Samuel F. Berkovic, Andrew Evans, Wendy Kelso, Sarah Farrand, Samantha M. Loi, Mark Walterfang, Dennis Velakoulis
Publikováno v:
Acta Neuropsychiatrica. :1-12
Objective: People with neuropsychiatric symptoms often experience delay in accurate diagnosis. Although cerebrospinal fluid neurofilament light (CSF NfL) shows promise in distinguishing neurodegenerative disorders (ND) from psychiatric disorders (PSY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceaeb26ef3344729f790c1c6e61fc60a
https://doi.org/10.1017/neu.2023.25
https://doi.org/10.1017/neu.2023.25
Autor:
Katelyn Tadd, Thomas Rego, Frank Gaillard, Charles B. Malpas, Mark Walterfang, Dennis Velakoulis, Sarah Farrand
Publikováno v:
The Journal of Neuropsychiatry and Clinical Neurosciences. 35:184-191
The appropriateness and clinical utility of neuroimaging in psychiatric populations has been long debated, and the ambiguity of guideline recommendations is well established. Most of the literature is focused on first-episode psychosis. The investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cac726ff1f07ee153de9112feb5b76
https://doi.org/10.1176/appi.neuropsych.21110269
https://doi.org/10.1176/appi.neuropsych.21110269