Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Charles Alexandre Tournillac"'
Autor:
Josephine Schmaler, Mohammed Ullah, Franziska Boess, Birgit Molitor, Aynur Ekiciler, Alexandre Durrwell, Isabelle Walter, Brian Leonard, Nicole A. Kratochwil, Giorgio Ottaviani, Russell Jones, Charles Alexandre Tournillac, Florian Klammers, Yuyan Jin, Neil Parrott, Martina B. Mueller, Dan Turley, Stephen Fowler, Michaela Marschmann, Pierre-Alexis Gonsard, Miriam Triyatni
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 365:237-248
Long-term in vitro liver models are now widely explored for human hepatic metabolic clearance prediction, enzyme phenotyping, cross-species metabolism, comparison of low clearance drugs, and induction studies. Here, we present studies using a long-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58a3bb7e1d0e52e6b59ad6ff7a653e7
https://doi.org/10.1124/jpet.117.245712
https://doi.org/10.1124/jpet.117.245712
Autor:
Charles Alexandre Tournillac, Franz Schuler, Nicholas Flint, Volkmar Starke, Jean-Christophe Hoflack, Evelyne Chaput, Thomas Singer, Dalila Bachir-Cherif, Denise Blum, Annamaria Braendli-Baiocco, Nicole Justies, Genevieve Ubeaud-Sequier, Guido Steiner, Rachel Neff, Gonzalo Durán Pacheco, M. Haiker
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 41(8)
The bile duct-cannulated (BDC) rat is a standard animal model used in ADME experiments. The aim of this study was to investigate post-surgical alterations that are relevant to ADME investigations in BDC rats compared with sham- and non-operated anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bd65a388913890605e811353c589b0
https://pubmed.ncbi.nlm.nih.gov/21521079
https://pubmed.ncbi.nlm.nih.gov/21521079