Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Charles A. Valentine"'
Autor:
Laura W. Dillon, Jake Higgins, Hassan Nasif, Megan Othus, Lan Beppu, Thomas H. Smith, Elizabeth Schmidt, Charles C. Valentine III, Jesse J. Salk, Brent L Wood, Harry P. Erba, Jerald P. Radich, Christopher S. Hourigan
Publikováno v:
Haematologica, Vol 109, Iss 2 (2023)
The presence of measurable residual disease (MRD) is strongly associated with treatment outcomes in acute myeloid leukemia (AML). Despite the correlation with clinical outcomes, MRD assessment has yet to be standardized or routinely incorporated into
Externí odkaz:
https://doaj.org/article/5ddca69089a4412bafc0c569c3e4ed97
Akademický článek
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Autor:
Jesse J. Salk, Kaitlyn Loubet-Senear, Elisabeth Maritschnegg, Charles C. Valentine, Lindsey N. Williams, Jacob E. Higgins, Reinhard Horvat, Adriaan Vanderstichele, Daniela Nachmanson, Kathryn T. Baker, Mary J. Emond, Emily Loter, Maria Tretiakova, Thierry Soussi, Lawrence A. Loeb, Robert Zeillinger, Paul Speiser, Rosa Ana Risques
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 132-144.e3 (2019)
Summary: High-accuracy next-generation DNA sequencing promises a paradigm shift in early cancer detection by enabling the identification of mutant cancer molecules in minimally invasive body fluid samples. We demonstrate 80% sensitivity for ovarian c
Externí odkaz:
https://doaj.org/article/321fc6803f4e46e7a0f6986070caf555
Autor:
Stephanie L. Smith-Roe, Cheryl A. Hobbs, Victoria Hull, J. Todd Auman, Leslie Recio, Michael A. Streicker, Miriam V. Rivas, Gabriel A. Pratt, Fang Yin Lo, Jacob E. Higgins, Elizabeth K. Schmidt, Lindsey N. Williams, Daniela Nachmanson, Charles C. Valentine, Jesse J. Salk, Kristine L. Witt
Publikováno v:
bioRxiv
Duplex sequencing (DuplexSeq) is an error-corrected next-generation sequencing (ecNGS) method in which molecular barcodes informatically link PCR-copies back to their source DNA strands, enabling computational removal of errors by comparing grouped s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc6e7afac422b90213086f574be3047
https://doi.org/10.1101/2023.05.08.539833
https://doi.org/10.1101/2023.05.08.539833
Autor:
Annette E. Dodge, Danielle P.M. LeBlanc, Gu Zhou, Andrew Williams, Matthew J. Meier, Phu Van, Fang Yin Lo, Charles C. Valentine, Jesse J. Salk, Carole L. Yauk, Francesco Marchetti
Mutagenicity testing is an essential component of health safety assessment. Duplex Sequencing (DS), an emerging high-accuracy DNA sequencing technology, may provide substantial advantages over conventional mutagenicity assays. DS could be used to eli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a4e9772eacd5c77795f6b1185552eff
https://doi.org/10.1101/2023.02.23.529719
https://doi.org/10.1101/2023.02.23.529719
Autor:
Eunnara Cho, Carol D. Swartz, Andrew Williams, Miriam Rivas, Leslie Recio, Kristine L. Witt, Elizabeth K. Schmidt, Jeffry Yaplee, Thomas H. Smith, Phu Van, Fang Yin Lo, Charles C. Valentine, Jesse J. Salk, Francesco Marchetti, Stephanie L. Smith-Roe, Carole L. Yauk
Error-corrected Duplex Sequencing (DuplexSeq) enables direct quantification of low-frequency mutations and offers tremendous potential for chemical mutagenicity assessment. We investigated the utility of DuplexSeq to quantify induced mutation frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0297e7108e98c4ad7df2f12bf5adc5ad
https://doi.org/10.1101/2023.02.22.529418
https://doi.org/10.1101/2023.02.22.529418
Autor:
Elizabeth K. Schmidt, Roberta A. Mittelstaedt, Timothy W. Robison, Xuefei Cao, Ying Chen, Wei Sun, Rebecca Wynne, Yiying Wang, Levan Muskhelishvili, Charles C. Valentine, Thomas H. Smith, Lindsey N. Williams, Zachary K Norgaard, Robert H. Heflich, Kelly Davis, Jesse J. Salk, Jeffry Yaplee
Publikováno v:
Environmental and Molecular Mutagenesis
The organotypic human air‐liquid‐interface (ALI) airway tissue model has been used as an in vitro cell culture system for evaluating the toxicity of inhaled substances. ALI airway cultures are highly differentiated, which has made it challenging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2149b0742866ddafa9a6c2b7b5751dd5
http://europepmc.org/articles/PMC8251634
http://europepmc.org/articles/PMC8251634
Autor:
Eunnara Cho, Carol D. Swartz, Andrew Williams, Miriam Rivas, Leslie Recio, Kristine L. Witt, Elizabeth K. Schmidt, Jeffry Yaplee, Thomas H. Smith, Phu Van, Fang Yin Lo, Charles C. Valentine, Jesse J. Salk, Francesco Marchetti, Stephanie L. Smith-Roe, Carole L. Yauk
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :503649
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0a524563e12aaae39a071bda2cdd3cc
https://doi.org/10.1016/j.mrgentox.2023.503649
https://doi.org/10.1016/j.mrgentox.2023.503649
Autor:
Masumi Ueda, Jake Higgins, Thomas Smith, Elizabeth Schmidt, Fang Y. Lo, Charles C. Valentine, Jesse J. Salk, Rainer Storb, Jerald P. Radich
Publikováno v:
Cancer Research. 82:LB063-LB063
Clonal hematopoiesis (CH aka CHIP) is the process whereby otherwise healthy individuals accumulate clones bearing low-frequency somatic mutations in hematologic malignancy (HM) driver genes. Historically thought to be a phenomenon of the elderly that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1979e866f504861f946f6c96605059b
https://doi.org/10.1158/1538-7445.am2022-lb063
https://doi.org/10.1158/1538-7445.am2022-lb063
Autor:
Thomas H. Smith, Jake E. Higgins, Fang Y. Lo, Michael J. Hipp, Charles C. Valentine, Amanda R. Leonti, Rhonda E. Ries, Soheil Meshinchi, Benjamin J. Huang, Jesse J. Salk
Publikováno v:
Cancer Research. 82:A009-A009
Rationale: Accurate and sensitive detection of measurable residual disease (MRD) is critical for clinical management and the development of new therapies for pediatric acute myeloid leukemia (AML). The presence of MRD is a well-established predictor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac4b2f332afab292733ea19a780173fe
https://doi.org/10.1158/1538-7445.evodyn22-a009
https://doi.org/10.1158/1538-7445.evodyn22-a009