Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Charles A. Lessman"'
Autor:
Charles A. Lessman, Nikki A Brantley
Publikováno v:
Zygote. 28:322-332
SummaryTransparentCasperzebrafish allow studies of vertebrate sexual maturation and gonad developmentin vivo.Caspergonad dynamics can be observed longitudinally over time and non-invasively. Gonad maturation and reproduction are complex processes sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd18ee5ad320d1ff6d35fadf8f74738
https://doi.org/10.1017/s0967199420000180
https://doi.org/10.1017/s0967199420000180
Autor:
Yiai Tong, David Finkelstein, Bensheng Ju, Jason Dapper, Richard J. Gilbertson, Nidal Boulos, Michael R. Taylor, Radhika Thiruvenkatam, Christopher J. Eden, Birgit Nimmervoll, Charles A. Lessman, Mohankumar Murugesan, Timothy N. Phoenix, Karen Wright, David W. Ellison
Publikováno v:
Oncogene
High-throughput screens (HTS) of compound toxicity against cancer cells can identify thousands of potential new drug-leads. But only limited numbers of these compounds can progress to expensive and labor intensive efficacy studies in mice, creating a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a64bc464459eaafa51b1a2a14db48b3
http://europepmc.org/articles/PMC4205223
http://europepmc.org/articles/PMC4205223
Autor:
Nikki A Brantley, Charles A. Lessman
Publikováno v:
Mechanisms of Development. 160:103582
Important aspects of vertebrate reproduction, such as gametogenesis, involve changes in organs found deep internally and thus not easily studied directly in most living vertebrates due to obscuring pigment and overlying tissues. Transparent lines of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc16bbc4dd89f9c84b2377018763338a
https://doi.org/10.1016/j.mod.2019.103582
https://doi.org/10.1016/j.mod.2019.103582
Autor:
Jianxiong Liu, Charles A. Lessman
Publikováno v:
ISRN Developmental Biology. 2013:1-11
We investigated the distribution ofγ-tubulin in zebrafish oocytes and embryos using epifluorescent or confocal microscopy andγ-tubulin antibodies. During meiotic maturation of zebrafish oocytes,γ-tubulin begins redistribution from oocyte ooplasm a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f21bc028c4af9684a1cddc6499e269
https://doi.org/10.1155/2013/920265
https://doi.org/10.1155/2013/920265
Autor:
Charles A. Lessman
Publikováno v:
Birth Defects Research Part C: Embryo Today: Reviews. 93:268-280
The zebrafish, Danio rerio, a small, tropical freshwater species native to Pakistan and India, has become a National Institutes of Health-sanctioned model organism and, due to its many advantages as an experimental vertebrate, it has garnered intense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9348596763c3f5f74618b09bbdf71775
https://doi.org/10.1002/bdrc.20212
https://doi.org/10.1002/bdrc.20212
Autor:
Charles A. Lessman
Publikováno v:
General and Comparative Endocrinology. 161:53-57
The process of oogenesis culminates in steroid-induced oocyte maturation to produce the fertilizable egg. A quintessential biological entity, the egg is central to the production of new individuals. The result of egg fertilization by a sperm cell is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c06d18a49cfeefb56dd0b058caf733f
https://doi.org/10.1016/j.ygcen.2008.11.004
https://doi.org/10.1016/j.ygcen.2008.11.004
Autor:
Charles A. Lessman, Jianxiong Liu
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 147:56-73
Tubulin dynamics, i.e., the interchange of polymeric and soluble forms, is important for microtubule (MTs) cellular functions, and thus plays essential roles in zebrafish oogenesis and embryogenesis. A novel finding in this study revealed that there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393ea61b4443fd76a67c690d223ec21b
https://doi.org/10.1016/j.cbpb.2006.12.014
https://doi.org/10.1016/j.cbpb.2006.12.014
Autor:
Charles A. Lessman
Publikováno v:
Real-Time Imaging. 8:189-201
The zebrafish (Danio rerio) is an exquisite vertebrate model system for the study of developmental mechanisms. The unraveling of these developmental processes at the molecular level will allow design of new treatments for a myriad of diseases, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7f85bb203cf0f69467ca83e9d61837a
https://doi.org/10.1006/rtim.2001.0282
https://doi.org/10.1006/rtim.2001.0282
Autor:
Charles A. Lessman
Publikováno v:
Cilia
Cilia, Vol 1, Iss 1, p 9 (2012)
Cilia, Vol 1, Iss 1, p 9 (2012)
Ever since Edouard Van Beneden and Theodor Boveri first formally described the centrosome in the late 1800s, it has captivated cell biologists. The name clearly indicated its central importance to cell functioning, even to these early investigators.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1b84e67dbfc13908b28eb51e24d570
https://pubmed.ncbi.nlm.nih.gov/23351173
https://pubmed.ncbi.nlm.nih.gov/23351173
Autor:
Charles A. Lessman
Publikováno v:
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 104:155-162
1. Tubulins from brain and testes of the frog (genus Rana) were purified by taxol and cyclic assembly-disassembly. 2. Attempts to purify ovarian tubulins by this same method were unsuccessful. 3. Oocyte fractions isolated in microtubule-stabilizing d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e20eb0c7f6f2377e948f8ad8db8c4ac
https://doi.org/10.1016/0305-0491(93)90352-6
https://doi.org/10.1016/0305-0491(93)90352-6