Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Charles A. Iii Gilson"'
Autor:
Liang-Shang Gan, Betty Tam, Khang Vu, Jinhua Piao, Douglas Marcotte, Shuo Zhao, Min Teng, Jianhua Chao, Charles A. Iii Gilson, Dikran Aivazian, Qin Wang, Guangqing Xiao, Arthur G. Taveras, Samina Khan, Tony Li, Junhua Fan, Jean-Yves Le Brazidec, Wen-Cherng Lee, Noel Timple, Khanh Nguyen, Lin Zhang, Jer-Hong Chong, Kevin Hong, Laura Silvian, Nicole Takeda, Mitchell Reff, Angela Cesena, Ron A. Morena, Deping Wang, Karen Lundgren, Leona E. Ling, Christina Boykin
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(18)
A novel class of pyrazolopyrimidine-sulfonamides was discovered as selective dual inhibitors of aurora kinase A (AKA) and cyclin-dependent kinase 1 (CDK1). These inhibitors were originally designed based on an early lead (compound I). SAR development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c36dadf5f7bf00efcdb5a0ac2fe8944
https://pubmed.ncbi.nlm.nih.gov/21798738
https://pubmed.ncbi.nlm.nih.gov/21798738
Publikováno v:
ChemInform. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca6680d356604e44a5b7fc3c388976ec
https://doi.org/10.1002/chin.200607224
https://doi.org/10.1002/chin.200607224
Publikováno v:
The Journal of organic chemistry. 70(20)
[Chemical reaction: see text] The first synthesis of the C1-C13 fragment of 2,3-dihydrodorrigocin A has been achieved from 6-bromohexanoic acid in 14 linear steps and an overall yield of 2%. The configurations of the stereogenic centers C8, C9, and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e559f072098c69f767dba2bb2c32db6
https://pubmed.ncbi.nlm.nih.gov/16277352
https://pubmed.ncbi.nlm.nih.gov/16277352