Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Charles A. Dangler"'
Autor:
Brent Gardner, Alexis Ascah, Malcolm Gains, Simon Authier, Richard C. Khan-Malek, Colleen Mockbee, Nicholas P. Clayton, Charles A. Dangler, John McManus, Donghui Zhang, Joan Keutzer
Publikováno v:
Radiation research. 195(2)
Exposure to acute, high-dose, whole-body ionizing radiation results in bone marrow failure (hematopoietic acute radiation syndrome with resultant infection, bleeding, anemia, and increased risk of death). Sargramostim (yeast-derived rhu GM-CSF), a ye
Autor:
Charles A. Dangler, Arlin B. Rogers, Peter Greaves, Patricia Brander-Weber, Andrew Spencer, Takuji Tanaka, Michael R. Elwell, Thomas Nolte, Michael W. Leach, Arun R. Pandiri, Jerrold M. Ward, Cynthia C. Shackelford, Ulrich Deschl, Richard Hailey
Publikováno v:
Journal of Toxicologic Pathology
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) project is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP), and North Am
Publikováno v:
The Journal of Immunology. 166:1443-1447
Activation of inflammatory gene expression by the transcription factor NF-κB is a central pathway in many inflammatory disorders, including colitis. Increased NF-κB activity has been linked with development of colitis in humans and animal models, t
Autor:
Charles A. Dangler, Shilu Xu, Mark D. Schrenzel, Yan Feng, Mark T. Whary, N.H. Shomer, Floyd E. Dewhirst, James G. Fox, Bruce J. Paster
Publikováno v:
Experimental Biology and Medicine. 226:420-428
Helicobacter bilis and H. hepaticus, both urease-positive intestinal helicobacters of mice, have been shown experimentally to induce proliferative typhlocolitis in scid mice. We recently isolated a urease-negative Helicobacter sp. (H. sp.) that also
Autor:
Timothy C. Wang, Mark T. Whary, Hai Ning Shi, Cathryn Nagler-Anderson, James G. Fox, Paul L. Beck, Charles A. Dangler
Publikováno v:
Nature Medicine. 6:536-542
Helicobacter pylori is causally associated with gastritis and gastric cancer. Some developing countries with a high prevalence of infection have high gastric cancer rates, whereas in others, these rates are low. The progression of helicobacter-induce
Publikováno v:
Infection and Immunity. 68:2110-2118
Campylobacter fetusis a cause of enteritis and invasive extraintestinal disease in humans. In order to develop an animal model ofC. fetusinfection, outbred ICR SCID mice were orally challenged with a clinical isolate ofC. fetus. The stomachs of SCID
Autor:
Graham J. Dockray, James G. Fox, James R. Goldenring, Andrea Varro, Duan Chen, Timothy C. Wang, Charles A. Dangler, Theodore J. Koh, Sus Ito, Raktima Raychowdhury, Robert J. Coffey
Publikováno v:
Gastroenterology. 118:36-47
Background & Aims: Hypergastrinemia occurs frequently in association with acid suppression and Helicobacter infection, but its role in the progression to gastric atrophy and gastric cancer has not been well defined. Methods: The effects of hypergastr
Publikováno v:
Infection and Immunity. 66:3142-3148
Helicobacter hepaticus infection in A/JCr mice results in chronic active hepatitis characterized by perivascular, periportal, and parenchymal infiltrates of mononuclear and polymorphonuclear cells. This study examined the development of hepatitis and
Publikováno v:
Infection and Immunity. 66:2614-2618
Humans infected with Helicobacter pylori have abnormally low levels of the antioxidant vitamin C, which protects against the formation of carcinogenic nitrosamines, in gastric juice. Guinea pigs, like humans and nonhuman primates, have a dietary requ
Publikováno v:
Journal of Clinical Microbiology. 36:1382-1387
In a long-term rodent bioassay evaluating the carcinogenicity of triethanolamine, there was equivocal evidence of carcinogenic activity in male B6C3F 1 mice, based on a marginal increase in the number of hepatocellular adenomas and hepatoblastomas. I