Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Charles A. Brubaker"'
Autor:
Charles William Brubaker
Publikováno v:
The bulletin of the National Association of Secondary School Principals. 46:197-200
Publikováno v:
Blood. 25:13-22
1. Thirty-six children with leukemic involvement of the CNS were treated with one to seven courses of methotrexate given intrathecally. a. Complete or partial symptomatic relief occurred in 57 of 67 episodes treated. b. Onset of improvement ranged fr
Publikováno v:
Blood. 25:1-12
Observations on the course of 59 children who experienced 109 distinct episodes of CNS involvement by leukemia showed that: 1. This complication may be associated with all types of acute and subacute leukemia. 2. There is no single or combination of
Autor:
M. Lois Murphy, Charles A. Brubaker, John R. Hartmann, Edward B. Perrin, Sanford L. Leikin, James A. Wolff
Publikováno v:
Cancer. 21:346-351
Although prednisone has been effectively used to induce remission in acute leukemia, a controlled exploration of optimal dosage and of intermittent therapy has not been reported. Of 223 previously untreated children 86 received 2 mg/kg in three divid
Autor:
Charles William Brubaker
Publikováno v:
Annals of the New York Academy of Sciences. 142:522-530
Autor:
Robert S. Cleland, Charles A. Brubaker, Benjamin H. Landing, Merl J. Carson, David L. Chadwick
Publikováno v:
Pediatrics. 35:405-412
1. Thirteen boys are described who present a syndrome of chronic suppurative lymphadenitis, chronic dermatitis, chronic pulmonary disease, and hepatosplenomegaly, with an eventually fatal outcome. 2. The cases described appear to have the same basic
Publikováno v:
Blood. 32:997-1002
Three children with acute erythroleukemia were studied for chromosomal changes. Two of them had persistently normal karyotypes despite relapse. The third patient was missing a C chromosome, and had 45/46 mosaicism in the bone marrow and a dichotomy b
Autor:
Mila Pierce, John R. Hartmann, Charles A. Brubaker, William Krivit, Gilbert Thatcher, M. Lois Murphy
Publikováno v:
The Journal of Pediatrics. 68:965-968
A controlled study of two chemotherapeutic induction regimens in the treatment of229 patients with acute leukemia of childhood is reported. The efficacy of a combination of prednisone and 6-mercaptopurine was compared to that of prednisone and methot
Publikováno v:
The Journal of pediatrics. 70(4)
Induction of remission with prednisone in 330 children with acute leukemia resulted in improvement to complete remission in 40 per cent and in good partial remission in another 34 per cent of patients. Complete bone marrow remission occurred in 63 pe
Autor:
Charles A. Brubaker, Carol B. Hyman, Denman Hammond, Kenneth O. Williams, Nomie A. Shore, Gerald S. Gilchrist
Publikováno v:
The Journal of pediatrics. 73(4)
Summary 1. Daily oral prednisone (2 mg. per kilogram per day) and intermittent intravenous methotrexate (3 mg. per kilogram every 14 days) were used as initial therapy for 14 unselected children with acute lymphocytic or acute undifferentiated leukem