Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Charles A. B. Boucher"'
Autor:
Stephanie Popping, Lisbeth Versteegh, Brooke E. Nichols, David A. M. C. van de Vijver, Ard van Sighem, Peter Reiss, Suzanne Geerlings, Charles A. B. Boucher, Annelies Verbon
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Introduction In Europe, half of people living with HIV (PLWH) present late to care, with associated higher morbidity and mortality. This study aims to assess short- and long-term costs of HIV-care based on time of presentation and identify other fact
Externí odkaz:
https://doaj.org/article/a9b7a1e9d23f49a8b796173a1069ff9f
Autor:
Shringar Rao, Cynthia Lungu, Raquel Crespo, Thijs H. Steijaert, Alicja Gorska, Robert-Jan Palstra, Henrieke A. B. Prins, Wilfred van Ijcken, Yvonne M. Mueller, Jeroen J. A. van Kampen, Annelies Verbon, Peter D. Katsikis, Charles A. B. Boucher, Casper Rokx, Rob A. Gruters, Tokameh Mahmoudi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
DEAD-box polypeptide 3 (DDX3) is a host protein belonging to the family of ATP-dependent RNA helicases. Here, the authors demonstrate that DDX3 inhibitors reverse HIV-1 latency and selectively induce cell death in HIV-1-infected cell lines, primary C
Externí odkaz:
https://doaj.org/article/983a234271bf4954b9536cec417f77df
Autor:
Jeroen J. A. van Kampen, David A. M. C. van de Vijver, Pieter L. A. Fraaij, Bart L. Haagmans, Mart M. Lamers, Nisreen Okba, Johannes P. C. van den Akker, Henrik Endeman, Diederik A. M. P. J. Gommers, Jan J. Cornelissen, Rogier A. S. Hoek, Menno M. van der Eerden, Dennis A. Hesselink, Herold J. Metselaar, Annelies Verbon, Jurriaan E. M. de Steenwinkel, Georgina I. Aron, Eric C. M. van Gorp, Sander van Boheemen, Jolanda C. Voermans, Charles A. B. Boucher, Richard Molenkamp, Marion P. G. Koopmans, Corine Geurtsvankessel, Annemiek A. van der Eijk
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
Duration of infectious SARS-CoV-2 shedding is an important measure for improved disease control. Here, the authors use virus cultures of respiratory tract samples from COVID-19 patients and observe a median shedding duration of 8 days and a drop belo
Externí odkaz:
https://doaj.org/article/c7e3e45f30ad4101a9d757f7279aa206
Autor:
Stephanie Popping, Lize Cuypers, Mark A. A. Claassen, Guido E. van den Berk, Anja De Weggheleire, Joop E. Arends, Anne Boerekamps, Richard Molenkamp, Marion P. G. Koopmans, Annelies Verbon, Charles A. B. Boucher, Bart Rijnders, David A. M. C. van de Vijver
Publikováno v:
Viruses, Vol 14, Iss 9, p 1953 (2022)
Background: In the Netherlands, unrestricted access to direct-acting antivirals (DAAs) halved the incidence of acute hepatitis C virus (HCV) infections among HIV-infected men who have sex with men (MSM). To develop strategies that can further reduce
Externí odkaz:
https://doaj.org/article/da22468f481a430d87c80df0148ef996
Autor:
Luna Colagrossi, Lucas E. Hermans, Romina Salpini, Domenico Di Carlo, Suzan D. Pas, Marta Alvarez, Ziv Ben-Ari, Greet Boland, Bianca Bruzzone, Nicola Coppola, Carole Seguin-Devaux, Tomasz Dyda, Federico Garcia, Rolf Kaiser, Sukran Köse, Henrik Krarup, Ivana Lazarevic, Maja M. Lunar, Sarah Maylin, Valeria Micheli, Orna Mor, Simona Paraschiv, Dimitros Paraskevis, Mario Poljak, Elisabeth Puchhammer-Stöckl, François Simon, Maja Stanojevic, Kathrine Stene-Johansen, Nijaz Tihic, Pascale Trimoulet, Jens Verheyen, Adriana Vince, Snjezana Zidovec Lepej, Nina Weis, Tülay Yalcinkaya, Charles A. B. Boucher, Annemarie M. J. Wensing, Carlo F. Perno, Valentina Svicher, on behalf of the HEPVIR working group of the European Society for translational antiviral research (ESAR)
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background HBsAg immune-escape mutations can favor HBV-transmission also in vaccinated individuals, promote immunosuppression-driven HBV-reactivation, and increase fitness of drug-resistant strains. Stop-codons can enhance HBV oncogenic-prop
Externí odkaz:
https://doaj.org/article/162243061cbc414bb1ca08196034caa5
Autor:
Stephanie Popping, Valeria Cento, Carole Seguin-Devaux, Charles A. B. Boucher, Adolfo de Salazar, Eva Heger, Orna Mor, Murat Sayan, Dominique Salmon-Ceron, Nina Weis, Henrik B. Krarup, Robert J. de Knegt, Oana Săndulescu, Vladimir Chulanov, David A. M. C. van de Vijver, Federico García, Francesca Ceccherini-Silberstein
Publikováno v:
Viruses, Vol 14, Iss 1, p 16 (2021)
Background: Approximately 71 million people are still in need of direct-acting antiviral agents (DAAs). To achieve the World Health Organization Hepatitis C elimination goals, insight into the prevalence and influence of resistance associated substit
Externí odkaz:
https://doaj.org/article/bf2fab0a298440cea2aa10f456809e75
Autor:
Cynthia Lungu, Francesco A. Procopio, Ronald J. Overmars, Rob J. J. Beerkens, Jolanda J. C. Voermans, Shringar Rao, Henrieke A. B. Prins, Casper Rokx, Giuseppe Pantaleo, David A. M. C. van de Vijver, Tokameh Mahmoudi, Charles A. B. Boucher, Rob A. Gruters, Jeroen J. A. van Kampen
Publikováno v:
Viruses, Vol 12, Iss 9, p 973 (2020)
Substantial efforts to eliminate or reduce latent HIV-1 reservoirs are underway in clinical trials and have created a critical demand for sensitive, accurate, and reproducible tools to evaluate the efficacy of these strategies. Alternative reservoir
Externí odkaz:
https://doaj.org/article/c343245b74494b32b05a015c30171e4e
Autor:
Alina Kirichenko, Ilya Lapovok, Pavel Baryshev, David A. M. C. van de Vijver, Jeroen J. A. van Kampen, Charles A. B. Boucher, Dimitrios Paraskevis, Dmitry Kireev
Publikováno v:
Viruses, Vol 12, Iss 8, p 838 (2020)
The increasing use of the integrase strand transfer inhibitor (INSTI) class for the treatment of HIV-infection has pointed to the importance of analyzing the features of HIV-1 subtypes for an improved understanding of viral genetic variability in the
Externí odkaz:
https://doaj.org/article/b16e5b5e1a8946f5ab8dc3bb0a5ecf8c
Autor:
Shringar Rao, Cynthia Lungu, Raquel Crespo, Thijs H. Steijaert, Alicja Gorska, Robert-Jan Palstra, Henrieke A. B. Prins, Wilfred van Ijcken, Yvonne M. Mueller, Jeroen J. A. van Kampen, Annelies Verbon, Peter D. Katsikis, Charles A. B. Boucher, Casper Rokx, Rob A. Gruters, Tokameh Mahmoudi
An innovative approach to eliminate HIV-1-infected cells emerging out of latency, the major hurdle to HIV-1 cure, is to pharmacologically reactivate viral expression and concomitantly trigger intracellular pro-apoptotic pathways in order to selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da601c42bda14c90e49cd19dd92e3027
https://doi.org/10.1101/2020.08.26.266726
https://doi.org/10.1101/2020.08.26.266726
Publikováno v:
The Journal of antimicrobial chemotherapy. 71(6)
Dolutegravir is recommended as part of combination ART (cART) for HIV-1-infected patients. Toxicities, drug interactions and costs related to cART still warrant the search for improved treatment options. Dolutegravir's high resistance barrier might m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39750740bd051b258c66bb3368f6aa9e
https://pubmed.ncbi.nlm.nih.gov/27178829
https://pubmed.ncbi.nlm.nih.gov/27178829