Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Charles A. Ashley"'
Autor:
Sarah H. Kim, Arnaud Da Cruz Paula, Thais Basili, Higinio Dopeso, Rui Bi, Fresia Pareja, Edaise M. da Silva, Rodrigo Gularte-Mérida, Zhen Sun, Sho Fujisawa, Caitlin G. Smith, Lorenzo Ferrando, Ana Paula Martins Sebastião, Yonina Bykov, Anqi Li, Catarina Silveira, Charles W. Ashley, Anthe Stylianou, Pier Selenica, Wesley R. Samore, Achim A. Jungbluth, Dmitriy Zamarin, Nadeem R. Abu-Rustum, Kristian Helin, Robert A. Soslow, Jorge S. Reis-Filho, Esther Oliva, Britta Weigelt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Little is known about the genetics of sclerosing stromal tumor of the ovary, a rare type of sex cord-stromal tumor. Here, the authors use sequencing strategies to show that in a cohort of 26 tumor samples 65% carry a FHL2-GLI2 fusion gene and demonst
Externí odkaz:
https://doaj.org/article/47b2a974b2b14385a7cca2142adfd91e
Publikováno v:
Culture, Health & Sexuality, 2017 Jan 01. 19(7), 767-780.
Externí odkaz:
https://www.jstor.org/stable/26787781
Autor:
Charles W. Ashley, Pier Selenica, Juber Patel, Michelle Wu, Josip Nincevic, Yulia Lakhman, Qin Zhou, Ronak H. Shah, Michael F. Berger, Arnaud Da Cruz Paula, David N. Brown, Antonio Marra, Alexia Iasonos, Amir Momeni-Boroujeni, Kaled M. Alektiar, Kara Long Roche, Oliver Zivanovic, Jennifer J. Mueller, Dmitriy Zamarin, Vance A. Broach, Yukio Sonoda, Mario M. Leitao, Claire F. Friedman, Elizabeth Jewell, Jorge S. Reis-Filho, Lora H. Ellenson, Carol Aghajanian, Nadeem R. Abu-Rustum, Karen Cadoo, Britta Weigelt
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research.
Purpose: We sought to determine whether sequencing analysis of circulating cell-free DNA (cfDNA) in patients with prospectively accrued endometrial cancer captures the mutational repertoire of the primary lesion and allows for disease monitoring. Exp
Autor:
Charles W. Ashley, Kaled M. Alektiar, Britta Weigelt, Mario M. Leitao, Deborah F. DeLair, Karen Cadoo, D. Zamarin, Irina Tunnage, Arnaud Da Cruz Paula, Vicky Makker, Nadeem R. Abu-Rustum, Alicia Latham, Jennifer J. Mueller, Maria M. Rubinstein, David M. Hyman, Carol Aghajanian, Robert A. Soslow, Marina Stasenko, Claire F. Friedman
Publikováno v:
Gynecol Oncol
Objectives Assess outcomes of a clinical cohort of patients with endometrioid endometrial cancer (EEC) harboring somatic POLE exonuclease domain mutations (EDMs). Methods Patients were consented to a protocol of tumor-normal massively parallel sequen
Publikováno v:
Journal of Surgical Education. 76:1469-1475
Objective While current literature has explored the transferability of laparoscopic surgical skills to robotic surgery, this study looks to investigate the transferability of surgical skills between robotic surgical simulation and simulated tradition
Autor:
Kimberly Dessources, Kathryn M. Miller, Elizabeth Kertowidjojo, Arnaud Da Cruz Paula, Youran Zou, Pier Selenica, Edaise M. da Silva, Ryma Benayed, Charles W. Ashley, Nadeem R. Abu-Rustum, Snjezana Dogan, Robert A. Soslow, Martee L. Hensley, Britta Weigelt, Sarah Chiang
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 35(7)
High-grade endometrial stromal sarcomas (HGESSs) are more aggressive and have higher rates of resistance to endocrine therapy than low-grade endometrial stromal sarcomas (LGESSs). The pathogenesis of hormonal resistance in these lesions has yet to be
Autor:
Xin Pei, Jorge S. Reis-Filho, Nadeem Riaz, Diana Mandelker, Britta Weigelt, Rajesh Kumar, Charles W. Ashley, Arnaud Da Cruz Paula
Publikováno v:
Gynecologic Oncology. 152:11-19
OBJECTIVE: Mutational signatures provide insights into the biological processes shaping tumor genomes and may inform patient therapy. We sought to define the mutational signatures of i) endometrioid and serous endometrial carcinomas (ECs), stratified
Autor:
Andrea Gazzo, Jorge S. Reis-Filho, Lorenzo Ferrando, Paul Weisman, Rodrigo Gularte-Mérida, Sarah Chiang, Ana Paula Martins Sebastiao, Darya Buehler, Britta Weigelt, David N Brown, Fresia Pareja, Nadeem R. Abu-Rustum, Charles W. Ashley, Anthe Stylianou, Arnaud Da Cruz Paula
Publikováno v:
Histopathology
AIMS To characterise the genetic alterations in adult primary uterine rhabdomyosarcomas (uRMSs) and to investigate whether these tumours are genetically distinct from uterine carcinosarcomas (UCSs). METHODS AND RESULTS Three tumours originally diagno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419b6bbe8725cccffa8feb2d95a17be8
https://europepmc.org/articles/PMC8286280/
https://europepmc.org/articles/PMC8286280/
Autor:
Louise De Brot, Charles W. Ashley, Britta Weigelt, Robert A. Soslow, Sheila E. Segura, Niamh Conlon, Arnaud Da Cruz Paula, Deborah F. DeLair, Edaise M da Silva
Publikováno v:
Am J Surg Pathol
Endometrial carcinoma (EC), as described by Bokhman, has historically been classified as Type I (low-grade, hormone-dependant, young patients, good prognosis) or Type II (high-grade, hormone-independent, older patients, poor prognosis). This classifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afa3e36ba6e904d36212eeb803ad259
https://europepmc.org/articles/PMC7156312/
https://europepmc.org/articles/PMC7156312/
Autor:
Gulisa Turashvili, Robert A. Soslow, Charles W. Ashley, Kimberly Dessources, Cristina R. Antonescu, Esther Oliva, W. Glenn McCluggage, Yoshinao Oda, Kay J. Park, Arnaud Da Cruz Paula, Robert H. Young, Britta Weigelt, Martee L. Hensley, Youran Zou, Sabrina Croce, Sarah Chiang, Ryma Benayed, Stephen Yip, Cheng-Han Lee, Colin J.R. Stewart
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
High-grade histologic transformation of low-grade endometrial stromal sarcoma (LGESS) is rare. Here, we describe the clinicopathologic features and gene fusion status of 12 cases (11 primary uterine corpus and 1 primary vaginal), 11 diagnosed prospec