Zobrazeno 1 - 10
of 401
pro vyhledávání: '"Charles A Janeway"'
Autor:
Alexander Yu, Rudensky, Paula, Preston-Hurlburt, Soon-Cheol, Hong, Avlin, Barlow, Charles A, Janeway
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::185125653e9167d72c1521b8913cd26c
https://pubmed.ncbi.nlm.nih.gov/26802058
https://pubmed.ncbi.nlm.nih.gov/26802058
Autor:
David, Scheifele, Scott, Halperin, Barbara, Law, Arlene, King, Robert, Morris, Charles A, Janeway, Pierre, Déry, Marc, Lebel, Dorothy, Moore, Nicole, Le Saux, Elizabeth, Ford-Jones, Ben, Tan, Taj, Jadavji, Wendy, Vaudry, Wikke, Walop, Joanne, Embree, John, Waters
Publikováno v:
Canadian Medical Association Journal. 172:53-56
Background: Although vaccination of infants against Haemophilus influenzae type b (Hib) invasive infections is effective and has been routinely available in Canada since 1992, cases of the disease continue to occur. We were interested in determining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3718cc0aef1dbbc61f415e1cb4f3ba
https://doi.org/10.1503/cmaj.1031861
https://doi.org/10.1503/cmaj.1031861
Autor:
Joanne Daugherty, Mark J Shlomchik, Michelle Tang, Murugappan Ramanathan, Lynn G. Hannum, F. Susan Wong, Charles A Janeway, Li Wen, Irene Visintin
Publikováno v:
Diabetes. 53:2581-2587
B-cells are important in the development of type 1 diabetes, but their role is not completely defined. Although B-cells produce autoantibodies, these are not thought to be pathogenic; however, their antigen-presenting function is postulated to be cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe93aaa60521e43fcccf076cb39f3c58
https://doi.org/10.2337/diabetes.53.10.2581
https://doi.org/10.2337/diabetes.53.10.2581
Publikováno v:
Immunity. 19(3):317-328
Information on how suppressor/regulatory T cells can be generated directly in vivo and prevent autoimmunity remains fragmentary. We show here that epicutaneous immunization (ECi) with the immunodominant peptide of myelin basic protein (MBP), Ac1-11,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c6e60a3196af96ac254466ba2db87e
Publikováno v:
Proceedings of the National Academy of Sciences. 100:5354-5359
Thymocytes bearing the Eα52-68/I-A b complex-specific 1H3.1 αβ T cell antigen receptor are positively selected in Ab-Ep [Ab-Ep transgenic, invariant chain (Ii) −/− , I-Aβ b−/− ] mice, where I-A b molecules present only Eα52-68. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7919896e7c1cb8c4141b3e952bfb5fa2
https://doi.org/10.1073/pnas.0831129100
https://doi.org/10.1073/pnas.0831129100
Autor:
Sangwon V. Kim, Kim Bottomly, J. Magarian Blander, Richard A. Flavell, Derek B. Sant'Angelo, Daniela P. Metz, Charles A. Janeway
Publikováno v:
The Journal of Immunology. 170:2940-2948
The L51S mutation in the D10.G4.1 TCR α-chain reduces the affinity of the TCR to its ligand by affecting the interactions among the TCR, the β-chain of I-Ak, and the bound peptide. We show that this mutation drives the generation of a pool of memor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031c57d6c65189d72abaa9c1d1ae8fb7
https://doi.org/10.4049/jimmunol.170.6.2940
https://doi.org/10.4049/jimmunol.170.6.2940
Autor:
Charles A. Janeway, Marie Lagueux, Marie Meister, Jules A. Hoffmann, Emmanuel Perrodou, Daniel Doucet, Daniel Zachary, Anne-Isabelle Munier
Publikováno v:
EMBO reports. 3:1195-1200
Blood cells play a crucial role in both morphogenetic and immunological processes in Drosophila, yet the factors regulating their proliferation remain largely unknown. In order to address this question, we raised antibodies against a tumorous blood c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427d2f0b3bb3b877a7ca1ee031538111
https://doi.org/10.1093/embo-reports/kvf242
https://doi.org/10.1093/embo-reports/kvf242
Publikováno v:
European Journal of Immunology. 32:2510-2520
CD4 T cells recognize peptides bound to major histocompatibility complex (MHC) class II molecules. Most MHC class II molecules have four binding pockets occupied by amino acids 1, 4, 6, and 9 of the minimal peptide epitope, while the residues at posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c0e5a55c7e109a59b84e75f8254c56b
https://doi.org/10.1002/1521-4141(200209)32:9<2510::aid-immu2510>3.0.co
https://doi.org/10.1002/1521-4141(200209)32:9<2510::aid-immu2510>3.0.co
Role of genetic background in P selectin-dependent immune surveillance of the central nervous system
Publikováno v:
Journal of Neuroimmunology. 129:51-57
Although the blood–brain barrier and blood cerebrospinal fluid barrier maintain the central nervous system (CNS) as an immunologically privileged site, T lymphocytes can migrate through unstimulated brain endothelium and epithelium to perform immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d51287ccd4f6943b6b1403929df4db
https://doi.org/10.1016/s0165-5728(02)00172-8
https://doi.org/10.1016/s0165-5728(02)00172-8