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pro vyhledávání: '"Charles A Coomer"'
Autor:
Charles A Coomer, Irene Carlon-Andres, Maro Iliopoulou, Michael L Dustin, Ewoud B Compeer, Alex A Compton, Sergi Padilla-Parra
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009584 (2021)
[This corrects the article DOI: 10.1371/journal.ppat.1008359.].
Externí odkaz:
https://doaj.org/article/1ca77da391a84ad584cedd1fe6e59b48
Autor:
Kazi Rahman, Charles A Coomer, Saliha Majdoul, Selena Y Ding, Sergi Padilla-Parra, Alex A Compton
Publikováno v:
eLife, Vol 9 (2020)
The interferon-inducible transmembrane (IFITM) proteins belong to the Dispanin/CD225 family and inhibit diverse virus infections. IFITM3 reduces membrane fusion between cells and virions through a poorly characterized mechanism. Mutation of proline-r
Externí odkaz:
https://doaj.org/article/6d61b165ea014362a89fec8e64dae635
Autor:
Charles A Coomer, Irene Carlon-Andres, Maro Iliopoulou, Michael L Dustin, Ewoud B Compeer, Alex A Compton, Sergi Padilla-Parra
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008359 (2020)
There has been resurgence in determining the role of host metabolism in viral infection yet deciphering how the metabolic state of single cells affects viral entry and fusion remains unknown. Here, we have developed a novel assay multiplexing genetic
Externí odkaz:
https://doaj.org/article/c53ad4eca67b4c4a96160bb8ee44fc94
Autor:
Charles A Coomer, Sergi Padilla-Parra
Publikováno v:
Microscopy.
Identifying initial events of mucosal entry of human immunodeficiency virus type-1 (HIV-1) in laboratory-based, physiologically relevant and high-throughput contexts may aid in designing effective strategies to block local transmission and spread of
Publikováno v:
Trends in genetics : TIG. 37(5)
The CD225 superfamily regulates vesicular membrane fusion events essential to neurotransmission, immunity, development, and metabolism. Its importance to physiology is reinforced by the identification of polymorphisms associated with disease. This ar
Autor:
Charles A. Coomer, Thomas A. Bowden, Sergi Padilla-Parra, Yasunori Watanabe, Maro Iliopoulou, Luis Alvarez, Rory Nolan, G M Jakobsdottir
Publikováno v:
Nature structuralmolecular biology. 25(9)
Little is known about the intermolecular dynamics and stoichiometry of the interactions of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) protein with its receptors and co-receptors on the host cell surface. Here we analyze time-resol
Autor:
Wei Shao, John M. Coffin, Jonathan Spindler, Zandrea Ambrose, Christopher Kline, Nicholas Johnson, Mary F. Kearney, John W. Mellors, Charles Austin Coomer, Elizabeth M. Anderson, Luke Smith
Publikováno v:
Retrovirology
Background Determining the anatomic compartments that contribute to plasma HIV-1 is critical to understanding the sources of residual viremia during combination antiretroviral therapy (ART). We analyzed viral DNA and RNA populations in the plasma and
Autor:
Charles A. Coomer, Maro Iliopoulou, Irene Carlon-Andres, Sergi Padilla-Parra, Michael L. Dustin, Alex A. Compton, Ewoud B. Compeer
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008359 (2020)
PLoS Pathogens
PLOS Pathogens
PLoS Pathogens
PLOS Pathogens
There has been resurgence in determining the role of host metabolism in viral infection yet deciphering how the metabolic state of single cells affects viral entry and fusion remains unknown. Here, we have developed a novel assay multiplexing genetic