Zobrazeno 1 - 10
of 481
pro vyhledávání: '"Charles A, Mitchell"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
The structure of the leaf microbiome can alter host fitness and change in response to abiotic and biotic factors, like seasonality, climate, and leaf age. However, relatively few studies consider the influence of host age on microbial communities at
Externí odkaz:
https://doaj.org/article/5df4f31be9b74ad39e92d987b867406f
Autor:
Charles L. Mitchell, Dmitry Kurouski
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
An unprecedented extension of life expectancy observed during the past century drastically increased the number of patients diagnosed with Parkinson’s diseases (PD) worldwide. Estimated costs of PD alone reached $52 billion per year, making effecti
Externí odkaz:
https://doaj.org/article/74024e4e1bd246a9b06a0140aced2f3f
Autor:
Rita L Grunberg, Fletcher W Halliday, Robert W Heckman, Brooklynn N Joyner, Kayleigh R O'Keeffe, Charles E Mitchell
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0293495 (2023)
Disease may drive variation in host community structure by modifying the interplay of deterministic and stochastic processes that shape communities. For instance, deterministic processes like ecological selection can benefit species less impacted by
Externí odkaz:
https://doaj.org/article/6695e8258fb84e5494fd6a1b2b0c3608
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285129 (2023)
Host individuals are commonly coinfected with multiple parasite species that may interact to shape within-host parasite community structure. In addition to within-host species interactions, parasite communities may also be structured by other process
Externí odkaz:
https://doaj.org/article/e0599f7197dc4b6f834f360e7f560013
Autor:
Liyan Mao, Sylvia M. LaCourse, Soyeon Kim, Chang Liu, Bo Ning, Duran Bao, Jia Fan, Christopher J. Lyon, Ziyong Sun, Sharon Nachman, Charles D. Mitchell, Tony Y. Hu
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Non-sputum methods are urgently needed to improve tuberculosis diagnosis and treatment monitoring in children. This study evaluated the ability of a serum assay quantifying a species-specific peptide of the Mycobacterium tuberculo
Externí odkaz:
https://doaj.org/article/11abb6089acd4ca0a241b4aa76960ff6
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The interactions among host-associated microbes and parasites can have clear consequences for disease susceptibility and progression within host individuals. Yet, empirical evidence for how these interactions impact parasite transmission between host
Externí odkaz:
https://doaj.org/article/387584ba60a4457ebe34cde9877e7005
Publikováno v:
Current Oncology Reports. 25:659-669
Autor:
Jia Fan, Hedong Zhang, Duc T. Nguyen, Christopher J. Lyon, Charles D. Mitchell, Zhen Zhao, Edward A. Graviss, Ye Hu
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background HIV-associated immune defects inhibit tuberculosis (TB) diagnosis, promote development of extrapulmonary TB and paucibacillary pulmonary TB cases with atypical radiographic features, and increase TB relapse rates. We therefore ass
Externí odkaz:
https://doaj.org/article/e1d160515883404aa78649b05a72b2c8
Autor:
Wenshu Zheng, Sylvia M. LaCourse, Bofan Song, Dhiraj Kumar Singh, Mayank Khanna, Juan Olivo, Joshua Stern, Jaclyn N. Escudero, Carlos Vergara, Fangfang Zhang, Shaobai Li, Shu Wang, Lisa M. Cranmer, Zhen Huang, Christine M. Bojanowski, Duran Bao, Irene Njuguna, Yating Xiao, Dalton C. Wamalwa, Duc T. Nguyen, Li Yang, Elizabeth Maleche-Obimbo, Nhung Nguyen, Lili Zhang, Ha Phan, Jia Fan, Bo Ning, Chenzhong Li, Christopher J. Lyon, Edward A. Graviss, Grace John-Stewart, Charles D. Mitchell, Alistair J. Ramsay, Deepak Kaushal, Rongguang Liang, Eddy Pérez-Then, Tony Y. Hu
Publikováno v:
Nature Biomedical Engineering. 6:979-991
Sensitive and specific blood-based assays for the detection of pulmonary and extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses, particularly in children. Here we report a nanoparticle-enhanced immunoassay read by dar
Publikováno v:
Clinical and Experimental Dermatology.
Sarcomas arising in the skin are rare but potentially fatal. These tumours originate from mesenchymal cells and can be divided between those that arise in soft tissue and those arising from bone. General guidelines exist for the management of soft-ti